Fabrication And Characterization Of Eco-Friendly Denture Adhesive Filled With Starches For Dental Application

Starch is widely used in various industrial applications due to its good adhesiveness and many other excellent properties. However, there are still some drawbacks of native starch in terms of mechanical strength, but the limitations can be overcome by modification techniques. Since there is limited...

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Main Author:	Hilmi, Bazli
Format:	Thesis
Language:	English
Published:	2020
Subjects:	T Technology
Online Access:	http://eprints.usm.my/56066/1/Fabrication%20And%20Characterization%20Of%20Eco-Friendly%20Denture%20Adhesive%20Filled%20With%20Starches%20For%20Dental%20Application.pdf
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spelling	my-usm-ep.560662022-12-21T04:30:41Z Fabrication And Characterization Of Eco-Friendly Denture Adhesive Filled With Starches For Dental Application 2020-12-01 Hilmi, Bazli T Technology TA401-492 Materials of engineering and construction. Mechanics of materials Starch is widely used in various industrial applications due to its good adhesiveness and many other excellent properties. However, there are still some drawbacks of native starch in terms of mechanical strength, but the limitations can be overcome by modification techniques. Since there is limited involvement of starch in dental application and the current available denture adhesives are reported to have several limitations and shortcomings for example, lack of bonding strength to hold the denture, the starches are explored for its potential in denture adhesive. Hence, this research focuses on the development of new formulation of denture adhesives which is called as eco-friendly denture adhesives (EFDAs) by studying the effects of the addition of different types of native and modified starches as fillers in denture adhesive properties for dental applications. The properties such as tensile bonding strength (TBS), shear strength, adhesiveness, hardness, pH and solubility of fabricated EFDAs in comparison with a selected commercial denture adhesive (CDA) were investigated. The investigated starches were corn, potato, sago, tapioca and wheat. The EFDAs were prepared with 5, 10 and 15% of starch filler loading. The starches were modified via oxidation technique by using sodium hypochlorite (NaOCl) and hydrogen peroxide (H2O2). The characterization tests of starch powders such as particle size analysis (PSA), Fourier Transform Infrared (FTIR) spectroscopy and UltraViolet-visible (UV-vis) spectrometry were performed. The mechanical and physical tests such as TBS, shear strength, adhesiveness, hardness, pH test and solubility were conducted on the fabricated EFDAs. Furthermore, antimicrobial test by using agar well diffusion and broth dilution methods and cytotoxicity test by using an Alamar Blue (AB) and 3-(4,5-dimethyl-2-thiazolyl)-2,5-diphenyl-2H-tetrazolium bromide (MTT) assays for biological analysis were conducted. Mechanical analysis indicated that produced EFDAs have higher TBS, shear strength, adhesiveness and hardness as compared to the CDA with the increase percentage up to 121.8%, 162.3%, 368.2% and 343.5%, respectively. The optimum properties were associated with wheat starch filler loading at 5% and followed by corn, sago, potato, and tapioca starches. The properties also decreased as the starch filler loading increased to 10% and 15%. The EFDAs incorporated with peppermint oil and tea tree oil were inhibiting the growth of C. albicans, S. aureus and E. coli microorganisms and the EFDA samples were also non-toxic to the periodontal ligament fibroblasts (PDLFs) up to day four. EFDA has good potential to be used as a natural based denture adhesive due to the promising properties especially EFDA with wheat starch modified by NaOCl at 5% filler loading because it shows the highest mechanical properties as well as non-toxic effect which are important in biological environment. 2020-12 Thesis http://eprints.usm.my/56066/ http://eprints.usm.my/56066/1/Fabrication%20And%20Characterization%20Of%20Eco-Friendly%20Denture%20Adhesive%20Filled%20With%20Starches%20For%20Dental%20Application.pdf application/pdf en public phd doctoral Universiti Sains Malaysia Pusat Pengajian Kejuruteraan Bahan Sumber Mineral
institution	Universiti Sains Malaysia
collection	USM Institutional Repository
language	English
topic	T Technology T Technology
spellingShingle	T Technology T Technology Hilmi, Bazli Fabrication And Characterization Of Eco-Friendly Denture Adhesive Filled With Starches For Dental Application
description	Starch is widely used in various industrial applications due to its good adhesiveness and many other excellent properties. However, there are still some drawbacks of native starch in terms of mechanical strength, but the limitations can be overcome by modification techniques. Since there is limited involvement of starch in dental application and the current available denture adhesives are reported to have several limitations and shortcomings for example, lack of bonding strength to hold the denture, the starches are explored for its potential in denture adhesive. Hence, this research focuses on the development of new formulation of denture adhesives which is called as eco-friendly denture adhesives (EFDAs) by studying the effects of the addition of different types of native and modified starches as fillers in denture adhesive properties for dental applications. The properties such as tensile bonding strength (TBS), shear strength, adhesiveness, hardness, pH and solubility of fabricated EFDAs in comparison with a selected commercial denture adhesive (CDA) were investigated. The investigated starches were corn, potato, sago, tapioca and wheat. The EFDAs were prepared with 5, 10 and 15% of starch filler loading. The starches were modified via oxidation technique by using sodium hypochlorite (NaOCl) and hydrogen peroxide (H2O2). The characterization tests of starch powders such as particle size analysis (PSA), Fourier Transform Infrared (FTIR) spectroscopy and UltraViolet-visible (UV-vis) spectrometry were performed. The mechanical and physical tests such as TBS, shear strength, adhesiveness, hardness, pH test and solubility were conducted on the fabricated EFDAs. Furthermore, antimicrobial test by using agar well diffusion and broth dilution methods and cytotoxicity test by using an Alamar Blue (AB) and 3-(4,5-dimethyl-2-thiazolyl)-2,5-diphenyl-2H-tetrazolium bromide (MTT) assays for biological analysis were conducted. Mechanical analysis indicated that produced EFDAs have higher TBS, shear strength, adhesiveness and hardness as compared to the CDA with the increase percentage up to 121.8%, 162.3%, 368.2% and 343.5%, respectively. The optimum properties were associated with wheat starch filler loading at 5% and followed by corn, sago, potato, and tapioca starches. The properties also decreased as the starch filler loading increased to 10% and 15%. The EFDAs incorporated with peppermint oil and tea tree oil were inhibiting the growth of C. albicans, S. aureus and E. coli microorganisms and the EFDA samples were also non-toxic to the periodontal ligament fibroblasts (PDLFs) up to day four. EFDA has good potential to be used as a natural based denture adhesive due to the promising properties especially EFDA with wheat starch modified by NaOCl at 5% filler loading because it shows the highest mechanical properties as well as non-toxic effect which are important in biological environment.
format	Thesis
qualification_name	Doctor of Philosophy (PhD.)
qualification_level	Doctorate
author	Hilmi, Bazli
author_facet	Hilmi, Bazli
author_sort	Hilmi, Bazli
title	Fabrication And Characterization Of Eco-Friendly Denture Adhesive Filled With Starches For Dental Application
title_short	Fabrication And Characterization Of Eco-Friendly Denture Adhesive Filled With Starches For Dental Application
title_full	Fabrication And Characterization Of Eco-Friendly Denture Adhesive Filled With Starches For Dental Application
title_fullStr	Fabrication And Characterization Of Eco-Friendly Denture Adhesive Filled With Starches For Dental Application
title_full_unstemmed	Fabrication And Characterization Of Eco-Friendly Denture Adhesive Filled With Starches For Dental Application
title_sort	fabrication and characterization of eco-friendly denture adhesive filled with starches for dental application
granting_institution	Universiti Sains Malaysia
granting_department	Pusat Pengajian Kejuruteraan Bahan Sumber Mineral
publishDate	2020
url	http://eprints.usm.my/56066/1/Fabrication%20And%20Characterization%20Of%20Eco-Friendly%20Denture%20Adhesive%20Filled%20With%20Starches%20For%20Dental%20Application.pdf
_version_	1776101127923695616

Fabrication And Characterization Of Eco-Friendly Denture Adhesive Filled With Starches For Dental Application

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