Sonography assisted clot evacuation in early intracerebral haemorrhage

Spontaneous intracerebral haemorrhages (ICH) are an increasingly common condition that leads to severe morbidities and mortality. Early surgical evacuation of spontaneous supratentorial ICHs has not consistently been proven to be beneficial from multiple studies. We investigate the effectiveness...

Full description

Saved in:

Bibliographic Details
Main Author:	Gene, Teo Eu
Format:	Thesis
Language:	English
Published:	2020
Subjects:	R Medicine (General)
Online Access:	http://eprints.usm.my/56941/1/TEO%20EU%20GENE%20-%20e%2024.pdf
Tags:	Add Tag No Tags, Be the first to tag this record!

id	my-usm-ep.56941
record_format	uketd_dc
spelling	my-usm-ep.569412023-02-14T08:57:49Z Sonography assisted clot evacuation in early intracerebral haemorrhage 2020 Gene, Teo Eu R Medicine (General) Spontaneous intracerebral haemorrhages (ICH) are an increasingly common condition that leads to severe morbidities and mortality. Early surgical evacuation of spontaneous supratentorial ICHs has not consistently been proven to be beneficial from multiple studies. We investigate the effectiveness of ultrasound guided early surgical evacuation of spontaneous supratentorial ICHs with respect to the completeness of evacuation on radiological evaluation. We prospectively recruited 58 patients who presented to a tertiary Neurosurgery centre in Malaysia within 48 hours of ictus for a spontaneous supratentorial ICH and underwent surgical evacuation of clot between June 2017 to February 2019. The patients were randomly assigned to surgical evacuation of clot with or without intraoperative ultrasound guidance in 1:1 ratio. Pre operative and immediate post operative CT brain images were compared. The primary outcome was the completeness of clot evacuation measured via the (a x b x c)/2 formula. The patient or their family underwent a telephone interview 3 months post surgery to assess neurological outcome. 29 patients were randomly assigned to both early surgical evacuation of clot with and without intraoperative ultrasound guidance. All patients were followed up at 3 months. Patients in the surgical evacuation with intraoperative ultrasound guidance and without intraoperative ultrasound guidance had mean reductions of 88.7% and 86.9% respectively, which was statistically significant, p value = 0.022. Mortality rate at 3 months for both groups was 10.3% and 20.1% respectively. (OR 2.3, 95% CI 0.51 to 10.08; p = 0.285). Conclusion Ultrasound guided evacuation of spontaneous supratentorial ICHs increases the completeness of clot evacuation via radiological evaluation. 2020 Thesis http://eprints.usm.my/56941/ http://eprints.usm.my/56941/1/TEO%20EU%20GENE%20-%20e%2024.pdf application/pdf en public masters Universiti Sains Malaysia Pusat Pengajian Sains Perubatan
institution	Universiti Sains Malaysia
collection	USM Institutional Repository
language	English
topic	R Medicine (General)
spellingShingle	R Medicine (General) Gene, Teo Eu Sonography assisted clot evacuation in early intracerebral haemorrhage
description	Spontaneous intracerebral haemorrhages (ICH) are an increasingly common condition that leads to severe morbidities and mortality. Early surgical evacuation of spontaneous supratentorial ICHs has not consistently been proven to be beneficial from multiple studies. We investigate the effectiveness of ultrasound guided early surgical evacuation of spontaneous supratentorial ICHs with respect to the completeness of evacuation on radiological evaluation. We prospectively recruited 58 patients who presented to a tertiary Neurosurgery centre in Malaysia within 48 hours of ictus for a spontaneous supratentorial ICH and underwent surgical evacuation of clot between June 2017 to February 2019. The patients were randomly assigned to surgical evacuation of clot with or without intraoperative ultrasound guidance in 1:1 ratio. Pre operative and immediate post operative CT brain images were compared. The primary outcome was the completeness of clot evacuation measured via the (a x b x c)/2 formula. The patient or their family underwent a telephone interview 3 months post surgery to assess neurological outcome. 29 patients were randomly assigned to both early surgical evacuation of clot with and without intraoperative ultrasound guidance. All patients were followed up at 3 months. Patients in the surgical evacuation with intraoperative ultrasound guidance and without intraoperative ultrasound guidance had mean reductions of 88.7% and 86.9% respectively, which was statistically significant, p value = 0.022. Mortality rate at 3 months for both groups was 10.3% and 20.1% respectively. (OR 2.3, 95% CI 0.51 to 10.08; p = 0.285). Conclusion Ultrasound guided evacuation of spontaneous supratentorial ICHs increases the completeness of clot evacuation via radiological evaluation.
format	Thesis
qualification_level	Master's degree
author	Gene, Teo Eu
author_facet	Gene, Teo Eu
author_sort	Gene, Teo Eu
title	Sonography assisted clot evacuation in early intracerebral haemorrhage
title_short	Sonography assisted clot evacuation in early intracerebral haemorrhage
title_full	Sonography assisted clot evacuation in early intracerebral haemorrhage
title_fullStr	Sonography assisted clot evacuation in early intracerebral haemorrhage
title_full_unstemmed	Sonography assisted clot evacuation in early intracerebral haemorrhage
title_sort	sonography assisted clot evacuation in early intracerebral haemorrhage
granting_institution	Universiti Sains Malaysia
granting_department	Pusat Pengajian Sains Perubatan
publishDate	2020
url	http://eprints.usm.my/56941/1/TEO%20EU%20GENE%20-%20e%2024.pdf
_version_	1776101182954012672

Sonography assisted clot evacuation in early intracerebral haemorrhage

Similar Items