A study on dengue fever presentation and outcome in Hospital Universiti Sains Malaysia

Dengue fever is one of the most endemic infectious disease in Malaysia and the number of cases increases each year. Patients may present in various phases and forms of dengue, which can progress to severe dengue. The aims of this study were to determine the presentations of dengue infection and f...

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主要作者: Ismail, Abdullah Lutfi
格式: Thesis
語言:English
出版: 2020
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spelling my-usm-ep.572342023-03-09T06:44:23Z A study on dengue fever presentation and outcome in Hospital Universiti Sains Malaysia 2020 Ismail, Abdullah Lutfi RC31-1245 Internal medicine Dengue fever is one of the most endemic infectious disease in Malaysia and the number of cases increases each year. Patients may present in various phases and forms of dengue, which can progress to severe dengue. The aims of this study were to determine the presentations of dengue infection and factors associated with severe complications. Methods: This retrospective study involved patients aged 12 years and above with positive dengue infection presented to emergency department in our tertiary, suburban hospital and admitted, from year 2016-2018. Patients sociodemographic patterns, presentation and complications of dengue were identified. Factors associated with severe dengue were determined. Results: A total of 327 cases were included, with 66 patients (20.2%) contracted severe dengue. Most common symptoms was loss of appetite (75.2%), followed by fever (65.7%) and vomiting (55.7%). Most common complication was dengue shock syndrome (18.3%) followed by respiratory distress (1.2%). Factors predictive of severe dengue include shortness of breath (AOR 5.82, 95% CI 1.37-24.69, p=0.017), diarrhoea (AOR 0.49, 95% CI 0.27-0.91, p=0.023), tachycardia (AOR 2.85,95% CI 1.59-5.10, p=0.001 and hepatomegaly (AOR 2.76, 95% CI 1.24-6.18, p=0.013). Conclusions: Identifying factors predictive of severe dengue may help physicians in prioritizing the patients care and anticipate deterioration and complications. Factors associated with severe dengue in this study were shortness of breath, diarrhea, tachycardia and hepatomegaly. 2020 Thesis http://eprints.usm.my/57234/ http://eprints.usm.my/57234/1/DR%20ABDULLAH%20LUTFI%20BIN%20ISMAIL-OCR.pdf application/pdf en public masters Universiti Sains Malaysia Pusat Pengajian Sains Perubatan
institution Universiti Sains Malaysia
collection USM Institutional Repository
language English
topic RC31-1245 Internal medicine
spellingShingle RC31-1245 Internal medicine
Ismail, Abdullah Lutfi
A study on dengue fever presentation and outcome in Hospital Universiti Sains Malaysia
description Dengue fever is one of the most endemic infectious disease in Malaysia and the number of cases increases each year. Patients may present in various phases and forms of dengue, which can progress to severe dengue. The aims of this study were to determine the presentations of dengue infection and factors associated with severe complications. Methods: This retrospective study involved patients aged 12 years and above with positive dengue infection presented to emergency department in our tertiary, suburban hospital and admitted, from year 2016-2018. Patients sociodemographic patterns, presentation and complications of dengue were identified. Factors associated with severe dengue were determined. Results: A total of 327 cases were included, with 66 patients (20.2%) contracted severe dengue. Most common symptoms was loss of appetite (75.2%), followed by fever (65.7%) and vomiting (55.7%). Most common complication was dengue shock syndrome (18.3%) followed by respiratory distress (1.2%). Factors predictive of severe dengue include shortness of breath (AOR 5.82, 95% CI 1.37-24.69, p=0.017), diarrhoea (AOR 0.49, 95% CI 0.27-0.91, p=0.023), tachycardia (AOR 2.85,95% CI 1.59-5.10, p=0.001 and hepatomegaly (AOR 2.76, 95% CI 1.24-6.18, p=0.013). Conclusions: Identifying factors predictive of severe dengue may help physicians in prioritizing the patients care and anticipate deterioration and complications. Factors associated with severe dengue in this study were shortness of breath, diarrhea, tachycardia and hepatomegaly.
format Thesis
qualification_level Master's degree
author Ismail, Abdullah Lutfi
author_facet Ismail, Abdullah Lutfi
author_sort Ismail, Abdullah Lutfi
title A study on dengue fever presentation and outcome in Hospital Universiti Sains Malaysia
title_short A study on dengue fever presentation and outcome in Hospital Universiti Sains Malaysia
title_full A study on dengue fever presentation and outcome in Hospital Universiti Sains Malaysia
title_fullStr A study on dengue fever presentation and outcome in Hospital Universiti Sains Malaysia
title_full_unstemmed A study on dengue fever presentation and outcome in Hospital Universiti Sains Malaysia
title_sort study on dengue fever presentation and outcome in hospital universiti sains malaysia
granting_institution Universiti Sains Malaysia
granting_department Pusat Pengajian Sains Perubatan
publishDate 2020
url http://eprints.usm.my/57234/1/DR%20ABDULLAH%20LUTFI%20BIN%20ISMAIL-OCR.pdf
_version_ 1776101193031876608