Hyperamylasaemia and 6 hours post ERCP pancreatitis among patients attending Hospital Raja Perempuan Zainab II (HRPZ II)

Background: Pancreatitis remains a major complication of endoscopic retrograde cholangiopancreatography (ERCP) with a prevalence of 2%-9%.Young age, female gender, difficulty in bile duct cannulation, pancreatic sphincterotomy, and sphincter of Oddi dysfunction have been found to be risk factors....

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Main Author:	Mat, Ann Dasimakamalia
Format:	Thesis
Language:	English
Published:	2021
Subjects:	R Medicine
Online Access:	http://eprints.usm.my/57267/1/DR%20ANN%20DASIMAKAMALIA%20BT%20MAT-24%20pages.pdf
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spelling	my-usm-ep.572672023-03-14T08:42:06Z Hyperamylasaemia and 6 hours post ERCP pancreatitis among patients attending Hospital Raja Perempuan Zainab II (HRPZ II) 2021 Mat, Ann Dasimakamalia R Medicine RC799-869 Diseases of the digestive system. Gastroenterology Background: Pancreatitis remains a major complication of endoscopic retrograde cholangiopancreatography (ERCP) with a prevalence of 2%-9%.Young age, female gender, difficulty in bile duct cannulation, pancreatic sphincterotomy, and sphincter of Oddi dysfunction have been found to be risk factors. Serum amylase and lipase levels are regarded as useful markers for early diagnosis of pancreatitis. However timing of amylase level taken after ERCP is not standardised among different centres. This study is to determine association of post ERCP pancreatitis with 6-hour amylase level after ERCP. Methods: This is a retrospective review of patients undergoing ERCP in Hospital Raja Perempuan Zainab II from 1st January 2015 to 31st December 2018. Serum amylase level at 6-hour after ERCP and complications after ERCP were reviewed. The association of amylase level 6-hour after ERCP and pancreatitis was determined. Results: A total of 308 patients were included in this study of which 41 (13.3%) had post ERCP pancreatitis. Amylase level of more than 300IU at 6-hour after ERCP (p < 0.001) and sphincterotomy (p=0.028) associated with post ERCP pancreatitis. Conclusion: Post ERCP pancreatitis is associated with an increase in serum amylase level greater than 300IU at 6-hour after ERCP. 2021 Thesis http://eprints.usm.my/57267/ http://eprints.usm.my/57267/1/DR%20ANN%20DASIMAKAMALIA%20BT%20MAT-24%20pages.pdf application/pdf en public masters Universiti Sains Malaysia Pusat Pengajian Sains Perubatan
institution	Universiti Sains Malaysia
collection	USM Institutional Repository
language	English
topic	R Medicine R Medicine
spellingShingle	R Medicine R Medicine Mat, Ann Dasimakamalia Hyperamylasaemia and 6 hours post ERCP pancreatitis among patients attending Hospital Raja Perempuan Zainab II (HRPZ II)
description	Background: Pancreatitis remains a major complication of endoscopic retrograde cholangiopancreatography (ERCP) with a prevalence of 2%-9%.Young age, female gender, difficulty in bile duct cannulation, pancreatic sphincterotomy, and sphincter of Oddi dysfunction have been found to be risk factors. Serum amylase and lipase levels are regarded as useful markers for early diagnosis of pancreatitis. However timing of amylase level taken after ERCP is not standardised among different centres. This study is to determine association of post ERCP pancreatitis with 6-hour amylase level after ERCP. Methods: This is a retrospective review of patients undergoing ERCP in Hospital Raja Perempuan Zainab II from 1st January 2015 to 31st December 2018. Serum amylase level at 6-hour after ERCP and complications after ERCP were reviewed. The association of amylase level 6-hour after ERCP and pancreatitis was determined. Results: A total of 308 patients were included in this study of which 41 (13.3%) had post ERCP pancreatitis. Amylase level of more than 300IU at 6-hour after ERCP (p < 0.001) and sphincterotomy (p=0.028) associated with post ERCP pancreatitis. Conclusion: Post ERCP pancreatitis is associated with an increase in serum amylase level greater than 300IU at 6-hour after ERCP.
format	Thesis
qualification_level	Master's degree
author	Mat, Ann Dasimakamalia
author_facet	Mat, Ann Dasimakamalia
author_sort	Mat, Ann Dasimakamalia
title	Hyperamylasaemia and 6 hours post ERCP pancreatitis among patients attending Hospital Raja Perempuan Zainab II (HRPZ II)
title_short	Hyperamylasaemia and 6 hours post ERCP pancreatitis among patients attending Hospital Raja Perempuan Zainab II (HRPZ II)
title_full	Hyperamylasaemia and 6 hours post ERCP pancreatitis among patients attending Hospital Raja Perempuan Zainab II (HRPZ II)
title_fullStr	Hyperamylasaemia and 6 hours post ERCP pancreatitis among patients attending Hospital Raja Perempuan Zainab II (HRPZ II)
title_full_unstemmed	Hyperamylasaemia and 6 hours post ERCP pancreatitis among patients attending Hospital Raja Perempuan Zainab II (HRPZ II)
title_sort	hyperamylasaemia and 6 hours post ercp pancreatitis among patients attending hospital raja perempuan zainab ii (hrpz ii)
granting_institution	Universiti Sains Malaysia
granting_department	Pusat Pengajian Sains Perubatan
publishDate	2021
url	http://eprints.usm.my/57267/1/DR%20ANN%20DASIMAKAMALIA%20BT%20MAT-24%20pages.pdf
_version_	1776101194460037120

Hyperamylasaemia and 6 hours post ERCP pancreatitis among patients attending Hospital Raja Perempuan Zainab II (HRPZ II)

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