Neuronal activation in patients with mild and moderate traumatic brain injury during working memory tasks

Background and Objective Cognitive impairment in patients following TBI is a significant cause of morbidity both to patients and their families. Memory impairment is one of the most common complaint patients and their families have as it impairs patients’ daily function. Current neuroimaging mod...

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Main Author: Fitzrol, Diana Noma
Format: Thesis
Language:English
Published: 2020
Subjects:
Online Access:http://eprints.usm.my/57316/1/DR%20DIANA%20NOMA%20BINTI%20FITZROL-24%20pages.pdf
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spelling my-usm-ep.573162023-03-14T09:09:43Z Neuronal activation in patients with mild and moderate traumatic brain injury during working memory tasks 2020 Fitzrol, Diana Noma R Medicine RC31-1245 Internal medicine Background and Objective Cognitive impairment in patients following TBI is a significant cause of morbidity both to patients and their families. Memory impairment is one of the most common complaint patients and their families have as it impairs patients’ daily function. Current neuroimaging modalities allows us to study the neuronal activation relevant to working memory in patients. Methods Patients who sustained mTBI/ modTBI, between the age of 18 to 65 years old and managed in Hospital Universiti Sains Malaysia were recruited into the study. These patients and a control group underwent fMRI scanning where they concurrently performed n-back tasks of 4 different memory loads. These fMRI scans were performed at 6 to 10 weeks postinjury and at 6 months post-injury. These cohort of subjects also had neuropsychology assessments performed at the same two time period as the fMRI. Results 2020 Thesis http://eprints.usm.my/57316/ http://eprints.usm.my/57316/1/DR%20DIANA%20NOMA%20BINTI%20FITZROL-24%20pages.pdf application/pdf en public masters Pusat Pengajian Sains Perubatan Pusat Pengajian Sains Perubatan
institution Universiti Sains Malaysia
collection USM Institutional Repository
language English
topic R Medicine
RC31-1245 Internal medicine
spellingShingle R Medicine
RC31-1245 Internal medicine
Fitzrol, Diana Noma
Neuronal activation in patients with mild and moderate traumatic brain injury during working memory tasks
description Background and Objective Cognitive impairment in patients following TBI is a significant cause of morbidity both to patients and their families. Memory impairment is one of the most common complaint patients and their families have as it impairs patients’ daily function. Current neuroimaging modalities allows us to study the neuronal activation relevant to working memory in patients. Methods Patients who sustained mTBI/ modTBI, between the age of 18 to 65 years old and managed in Hospital Universiti Sains Malaysia were recruited into the study. These patients and a control group underwent fMRI scanning where they concurrently performed n-back tasks of 4 different memory loads. These fMRI scans were performed at 6 to 10 weeks postinjury and at 6 months post-injury. These cohort of subjects also had neuropsychology assessments performed at the same two time period as the fMRI. Results
format Thesis
qualification_level Master's degree
author Fitzrol, Diana Noma
author_facet Fitzrol, Diana Noma
author_sort Fitzrol, Diana Noma
title Neuronal activation in patients with mild and moderate traumatic brain injury during working memory tasks
title_short Neuronal activation in patients with mild and moderate traumatic brain injury during working memory tasks
title_full Neuronal activation in patients with mild and moderate traumatic brain injury during working memory tasks
title_fullStr Neuronal activation in patients with mild and moderate traumatic brain injury during working memory tasks
title_full_unstemmed Neuronal activation in patients with mild and moderate traumatic brain injury during working memory tasks
title_sort neuronal activation in patients with mild and moderate traumatic brain injury during working memory tasks
granting_institution Pusat Pengajian Sains Perubatan
granting_department Pusat Pengajian Sains Perubatan
publishDate 2020
url http://eprints.usm.my/57316/1/DR%20DIANA%20NOMA%20BINTI%20FITZROL-24%20pages.pdf
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