Evaluation Of Haemoglobin Level and Platelet Count In Neonates With And Without Retinopathy Of Prematurity

Aim: Haemoglobin and platelet have been postulated to play a role in the development of retinopathy of prematurity (ROP). This study aimed to compare weekly mean haemoglobin level and platelet count between ROP and non-ROP infants in the first six weeks of life. Method: Ninety-three premature inf...

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Main Author:	Di, Lim Zi
Format:	Thesis
Language:	English
Published:	2021
Subjects:	RJ251-325 Newborn infants Including physiology care treatment diseases
Online Access:	http://eprints.usm.my/58833/1/Lim%20Zi%20Di-24%20pages.pdf
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spelling	my-usm-ep.588332023-07-06T05:11:42Z Evaluation Of Haemoglobin Level and Platelet Count In Neonates With And Without Retinopathy Of Prematurity 2021 Di, Lim Zi RJ251-325 Newborn infants Including physiology, care, treatment, diseases Aim: Haemoglobin and platelet have been postulated to play a role in the development of retinopathy of prematurity (ROP). This study aimed to compare weekly mean haemoglobin level and platelet count between ROP and non-ROP infants in the first six weeks of life. Method: Ninety-three premature infants with birth weight less than 1.5 kg and gestational age less than 32 weeks were recruited in Hospital Universiti Sains Malaysia from 2017 to 2019. Each ROP case was individually matched (1: 2) to two non-ROP cases. Weekly mean haemoglobin level, weekly mean platelet count, and other related risk factors were documented. Result: Thirty-one infants with ROP and 62 infants with non-ROP were recruited. Of those with ROP, 8 had stage 1 ROP, 6 had stage 2 ROP, 16 had stage 3 ROP. The mean birth weight and gestational age of the ROP group was 962.2 g and 27.6 weeks while the non-ROP group was 1056.9 g and 28.5 weeks respectively. We found significant differences in the weekly mean platelet counts between ROP and non-ROP infants from week two to week six of life (p=0.003). A significant difference was also found when comparing weekly mean haemoglobin level at week one of life (p=0.003). However, no significant difference was found in the weekly mean platelet count (p=0.489) and weekly mean haemoglobin level (p=0.292) after adjusting to covariates. Conclusion: There is no significant difference in mean haemoglobin level and platelet count in the first six weeks of life between ROP and non-ROP infants after adjusting to confounding factors like sepsis, bronchopulmonary dysplasia and blood transfusion. 2021 Thesis http://eprints.usm.my/58833/ http://eprints.usm.my/58833/1/Lim%20Zi%20Di-24%20pages.pdf application/pdf en public masters Universiti Sains Malaysia Pusat Pengajian Sains Perubatan
institution	Universiti Sains Malaysia
collection	USM Institutional Repository
language	English
topic	RJ251-325 Newborn infants Including physiology care treatment diseases
spellingShingle	RJ251-325 Newborn infants Including physiology care treatment diseases Di, Lim Zi Evaluation Of Haemoglobin Level and Platelet Count In Neonates With And Without Retinopathy Of Prematurity
description	Aim: Haemoglobin and platelet have been postulated to play a role in the development of retinopathy of prematurity (ROP). This study aimed to compare weekly mean haemoglobin level and platelet count between ROP and non-ROP infants in the first six weeks of life. Method: Ninety-three premature infants with birth weight less than 1.5 kg and gestational age less than 32 weeks were recruited in Hospital Universiti Sains Malaysia from 2017 to 2019. Each ROP case was individually matched (1: 2) to two non-ROP cases. Weekly mean haemoglobin level, weekly mean platelet count, and other related risk factors were documented. Result: Thirty-one infants with ROP and 62 infants with non-ROP were recruited. Of those with ROP, 8 had stage 1 ROP, 6 had stage 2 ROP, 16 had stage 3 ROP. The mean birth weight and gestational age of the ROP group was 962.2 g and 27.6 weeks while the non-ROP group was 1056.9 g and 28.5 weeks respectively. We found significant differences in the weekly mean platelet counts between ROP and non-ROP infants from week two to week six of life (p=0.003). A significant difference was also found when comparing weekly mean haemoglobin level at week one of life (p=0.003). However, no significant difference was found in the weekly mean platelet count (p=0.489) and weekly mean haemoglobin level (p=0.292) after adjusting to covariates. Conclusion: There is no significant difference in mean haemoglobin level and platelet count in the first six weeks of life between ROP and non-ROP infants after adjusting to confounding factors like sepsis, bronchopulmonary dysplasia and blood transfusion.
format	Thesis
qualification_level	Master's degree
author	Di, Lim Zi
author_facet	Di, Lim Zi
author_sort	Di, Lim Zi
title	Evaluation Of Haemoglobin Level and Platelet Count In Neonates With And Without Retinopathy Of Prematurity
title_short	Evaluation Of Haemoglobin Level and Platelet Count In Neonates With And Without Retinopathy Of Prematurity
title_full	Evaluation Of Haemoglobin Level and Platelet Count In Neonates With And Without Retinopathy Of Prematurity
title_fullStr	Evaluation Of Haemoglobin Level and Platelet Count In Neonates With And Without Retinopathy Of Prematurity
title_full_unstemmed	Evaluation Of Haemoglobin Level and Platelet Count In Neonates With And Without Retinopathy Of Prematurity
title_sort	evaluation of haemoglobin level and platelet count in neonates with and without retinopathy of prematurity
granting_institution	Universiti Sains Malaysia
granting_department	Pusat Pengajian Sains Perubatan
publishDate	2021
url	http://eprints.usm.my/58833/1/Lim%20Zi%20Di-24%20pages.pdf
_version_	1776101237175877632

Evaluation Of Haemoglobin Level and Platelet Count In Neonates With And Without Retinopathy Of Prematurity

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