A silver alginate coated dressing to reduce catheter-related bloodstream infection (CRBSI) among adult ICU patient: a randomised controlled trial

Background: Catheter-related bloodstream infection (CRBSI) is a bloodstream infection related to the presence of a central venous catheter (CVC) in the patient's vein. Many types of dressing have been used on CVC to reduce the numbers of CRBSI. However, the most ideal dressing to reduce CRBS...

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Main Author:	Ruslan, Muhammad Rosnal
Format:	Thesis
Language:	English
Published:	2020
Subjects:	RC666-701 Diseases of the circulatory (Cardiovascular) system
Online Access:	http://eprints.usm.my/58922/1/MUHAMMAD%20ROSNAL%20RUSLAN-24%20pages.pdf
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spelling	my-usm-ep.589222023-08-06T08:07:03Z A silver alginate coated dressing to reduce catheter-related bloodstream infection (CRBSI) among adult ICU patient: a randomised controlled trial 2020 Ruslan, Muhammad Rosnal RC666-701 Diseases of the circulatory (Cardiovascular) system Background: Catheter-related bloodstream infection (CRBSI) is a bloodstream infection related to the presence of a central venous catheter (CVC) in the patient's vein. Many types of dressing have been used on CVC to reduce the numbers of CRBSI. However, the most ideal dressing to reduce CRBSI is still under study. The aim of this study is to evaluate the effectiveness of silver alginate dressing in reducing CRBSI in comparison to conventional dressing. Methods: A total of 98 ICU patient from Hospital Universiti Sains Malaysia, Kelantan that were indicated for CVC insertion were divided randomly into two groups; Group 1 for silver alginate dressing (n=49) and Group 2 for conventional dressing (n=49). The CVC was subsequently applied with either silver alginate dressing or conventional dressing. Blood culture was withdrawn from the CVC lumen on day 6 of catheter placement or earlier if infection was suspected or prior removal of the catheter in the patient whose catheter no longer needed before 6th day. CVC was removed as soon as possible if no longer required or suspicious of catheter-related infection or when the duration was more than 14 days. Demographic data, catheter colonization, the occurrence of local infection and CRBSI will be recorded. Results: No subject in silver alginate group developed CRBSI and one subject in the conventional dressing group developed CRBSI, respectively (n=0, 0% vs n=1, 2.1%, P=0.99). Total of four subjects developed catheter colonization: one subject in silver alginate group and three subjects in the conventional dressing group, respectively (n=1, 2.1% vs n=3, 6.1%, P=0.617). Total of four subjects developed local infection: one subject in silver alginate group and three subjects in the conventional dressing group, respectively (n=1, 2.1% vs n=3, 6.1%, p=0.617). Silver alginate dressing group showed less proportion of CRBSI, catheter colonization and local infection compared to conventional dressing. However, these results were not statistically significant with p>0.05. Conclusion: Silver alginate dressing is not effective in reducing CRBSI, catheter colonization and local infection compared to conventional dressing. 2020 Thesis http://eprints.usm.my/58922/ http://eprints.usm.my/58922/1/MUHAMMAD%20ROSNAL%20RUSLAN-24%20pages.pdf application/pdf en public masters Universiti Sains Malaysia Pusat Pengajian Sains Perubatan
institution	Universiti Sains Malaysia
collection	USM Institutional Repository
language	English
topic	RC666-701 Diseases of the circulatory (Cardiovascular) system
spellingShingle	RC666-701 Diseases of the circulatory (Cardiovascular) system Ruslan, Muhammad Rosnal A silver alginate coated dressing to reduce catheter-related bloodstream infection (CRBSI) among adult ICU patient: a randomised controlled trial
description	Background: Catheter-related bloodstream infection (CRBSI) is a bloodstream infection related to the presence of a central venous catheter (CVC) in the patient's vein. Many types of dressing have been used on CVC to reduce the numbers of CRBSI. However, the most ideal dressing to reduce CRBSI is still under study. The aim of this study is to evaluate the effectiveness of silver alginate dressing in reducing CRBSI in comparison to conventional dressing. Methods: A total of 98 ICU patient from Hospital Universiti Sains Malaysia, Kelantan that were indicated for CVC insertion were divided randomly into two groups; Group 1 for silver alginate dressing (n=49) and Group 2 for conventional dressing (n=49). The CVC was subsequently applied with either silver alginate dressing or conventional dressing. Blood culture was withdrawn from the CVC lumen on day 6 of catheter placement or earlier if infection was suspected or prior removal of the catheter in the patient whose catheter no longer needed before 6th day. CVC was removed as soon as possible if no longer required or suspicious of catheter-related infection or when the duration was more than 14 days. Demographic data, catheter colonization, the occurrence of local infection and CRBSI will be recorded. Results: No subject in silver alginate group developed CRBSI and one subject in the conventional dressing group developed CRBSI, respectively (n=0, 0% vs n=1, 2.1%, P=0.99). Total of four subjects developed catheter colonization: one subject in silver alginate group and three subjects in the conventional dressing group, respectively (n=1, 2.1% vs n=3, 6.1%, P=0.617). Total of four subjects developed local infection: one subject in silver alginate group and three subjects in the conventional dressing group, respectively (n=1, 2.1% vs n=3, 6.1%, p=0.617). Silver alginate dressing group showed less proportion of CRBSI, catheter colonization and local infection compared to conventional dressing. However, these results were not statistically significant with p>0.05. Conclusion: Silver alginate dressing is not effective in reducing CRBSI, catheter colonization and local infection compared to conventional dressing.
format	Thesis
qualification_level	Master's degree
author	Ruslan, Muhammad Rosnal
author_facet	Ruslan, Muhammad Rosnal
author_sort	Ruslan, Muhammad Rosnal
title	A silver alginate coated dressing to reduce catheter-related bloodstream infection (CRBSI) among adult ICU patient: a randomised controlled trial
title_short	A silver alginate coated dressing to reduce catheter-related bloodstream infection (CRBSI) among adult ICU patient: a randomised controlled trial
title_full	A silver alginate coated dressing to reduce catheter-related bloodstream infection (CRBSI) among adult ICU patient: a randomised controlled trial
title_fullStr	A silver alginate coated dressing to reduce catheter-related bloodstream infection (CRBSI) among adult ICU patient: a randomised controlled trial
title_full_unstemmed	A silver alginate coated dressing to reduce catheter-related bloodstream infection (CRBSI) among adult ICU patient: a randomised controlled trial
title_sort	silver alginate coated dressing to reduce catheter-related bloodstream infection (crbsi) among adult icu patient: a randomised controlled trial
granting_institution	Universiti Sains Malaysia
granting_department	Pusat Pengajian Sains Perubatan
publishDate	2020
url	http://eprints.usm.my/58922/1/MUHAMMAD%20ROSNAL%20RUSLAN-24%20pages.pdf
_version_	1776101244571484160

A silver alginate coated dressing to reduce catheter-related bloodstream infection (CRBSI) among adult ICU patient: a randomised controlled trial

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