Development And Evaluation Of A Guideline On Potassium Chloride Intravenous Supplementation: Effectiveness, Safety And Cost Implications
The concentrated potassium chloride injection used in intravenous supplementation of potassium in hypokalemia is associated with risks of hyperkalemia and medication error. This study aimed to develop a guideline on potassium chloride intravenous supplementation with the emphasis of using premix...
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my-usm-ep.592562023-08-24T07:26:25Z Development And Evaluation Of A Guideline On Potassium Chloride Intravenous Supplementation: Effectiveness, Safety And Cost Implications 2022-08 Hirman, Melissa Mohammad RS1-441 Pharmacy and materia medica The concentrated potassium chloride injection used in intravenous supplementation of potassium in hypokalemia is associated with risks of hyperkalemia and medication error. This study aimed to develop a guideline on potassium chloride intravenous supplementation with the emphasis of using premixed formulations and evaluate its safety, effectiveness and cost implications. In Phase I of this study, a nationwide survey was conducted among 207 Malaysian hospital physicians. The findings suggested that there were variations in Malaysian physician’s prescribing practice of intravenous potassium supplementation in the treatment of hypokalemia. Data analysis revealed different physicians background resulted in different prescribing practices which may be due to the complexity of patient’s clinical conditions and medications. This poses a challenge for prescribers to treat hypokalemia and supports the need to have a practical or general guideline that can be used under different clinical conditions. This survey also revealed that Malaysian physicians favoured premixed potassium chloride formulations where physicians find it would ease usage and is safer for the patient. In Phase II of this study, a guideline with emphasis of premixed formulations was developed and implemented in a private hospital. 2022-08 Thesis http://eprints.usm.my/59256/ http://eprints.usm.my/59256/1/MELISSA%20BINTI%20MOHAMMAD%20HIRMAN%20-%20TESIS%20cut.pdf application/pdf en public phd doctoral Universiti Sains Malaysia Pusat Pengajian Sains Farmasi |
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Universiti Sains Malaysia |
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USM Institutional Repository |
| language |
English |
| topic |
RS1-441 Pharmacy and materia medica |
| spellingShingle |
RS1-441 Pharmacy and materia medica Hirman, Melissa Mohammad Development And Evaluation Of A Guideline On Potassium Chloride Intravenous Supplementation: Effectiveness, Safety And Cost Implications |
| description |
The concentrated potassium chloride injection used in intravenous
supplementation of potassium in hypokalemia is associated with risks of
hyperkalemia and medication error. This study aimed to develop a guideline on
potassium chloride intravenous supplementation with the emphasis of using
premixed formulations and evaluate its safety, effectiveness and cost implications. In
Phase I of this study, a nationwide survey was conducted among 207 Malaysian
hospital physicians. The findings suggested that there were variations in Malaysian
physician’s prescribing practice of intravenous potassium supplementation in the
treatment of hypokalemia. Data analysis revealed different physicians background
resulted in different prescribing practices which may be due to the complexity of
patient’s clinical conditions and medications. This poses a challenge for prescribers
to treat hypokalemia and supports the need to have a practical or general guideline
that can be used under different clinical conditions. This survey also revealed that
Malaysian physicians favoured premixed potassium chloride formulations where
physicians find it would ease usage and is safer for the patient. In Phase II of this
study, a guideline with emphasis of premixed formulations was developed and
implemented in a private hospital. |
| format |
Thesis |
| qualification_name |
Doctor of Philosophy (PhD.) |
| qualification_level |
Doctorate |
| author |
Hirman, Melissa Mohammad |
| author_facet |
Hirman, Melissa Mohammad |
| author_sort |
Hirman, Melissa Mohammad |
| title |
Development And Evaluation Of A
Guideline On Potassium Chloride
Intravenous Supplementation:
Effectiveness, Safety And Cost
Implications |
| title_short |
Development And Evaluation Of A
Guideline On Potassium Chloride
Intravenous Supplementation:
Effectiveness, Safety And Cost
Implications |
| title_full |
Development And Evaluation Of A
Guideline On Potassium Chloride
Intravenous Supplementation:
Effectiveness, Safety And Cost
Implications |
| title_fullStr |
Development And Evaluation Of A
Guideline On Potassium Chloride
Intravenous Supplementation:
Effectiveness, Safety And Cost
Implications |
| title_full_unstemmed |
Development And Evaluation Of A
Guideline On Potassium Chloride
Intravenous Supplementation:
Effectiveness, Safety And Cost
Implications |
| title_sort |
development and evaluation of a
guideline on potassium chloride
intravenous supplementation:
effectiveness, safety and cost
implications |
| granting_institution |
Universiti Sains Malaysia |
| granting_department |
Pusat Pengajian Sains Farmasi |
| publishDate |
2022 |
| url |
http://eprints.usm.my/59256/1/MELISSA%20BINTI%20MOHAMMAD%20HIRMAN%20-%20TESIS%20cut.pdf |
| _version_ |
1776101273548881920 |