The Effects Of Mitragynine On P-Glycoprotein Regulations And Its Neurotoxicity Mechanisms In Brain Cell Lines
The main objective is to determine the effects of mitragynine on P-gp regulations and neurotoxicity effects of drug-herb interactions between mitragynine and P-gp substrates in the PC12 cells using both in silico and in vitro approaches.
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Format: | Thesis |
Language: | English |
Published: |
2021
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Online Access: | http://eprints.usm.my/59299/1/MUHAMMAD%20ASYRAF%20BIN%20ABDURAMAN%20-%20TESIS%20cut.pdf |
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Summary: | The main objective is to determine the effects of mitragynine on P-gp regulations and neurotoxicity effects of drug-herb interactions between mitragynine and P-gp substrates in the PC12 cells using both in silico and in vitro approaches. |
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