Studies Of Capability, Stability, Toxicity And Bioefficacy Of Kenaf Based Cellulose Nanofiber As Larvicide Carrier For Mosquito Control

Mosquito-borne diseases are increasing every year and causing million deaths worldwide. The diseases are transmitted from the bite of an infected mosquito. Thus, it requires effective control measures to reduce the transmission rate, and one of the control strategies is using larvicide such as te...

Full description

Saved in:

Bibliographic Details
Main Author:	Pengiran, Hazirah
Format:	Thesis
Language:	English
Published:	2022
Subjects:	R5-920 Medicine (General)
Online Access:	http://eprints.usm.my/59361/1/HAZIRAH%20BINTI%20PENGIRAN%20-%20TESIS24.pdf
Tags:	Add Tag No Tags, Be the first to tag this record!

id	my-usm-ep.59361
record_format	uketd_dc
spelling	my-usm-ep.593612023-09-12T07:14:52Z Studies Of Capability, Stability, Toxicity And Bioefficacy Of Kenaf Based Cellulose Nanofiber As Larvicide Carrier For Mosquito Control 2022-06 Pengiran, Hazirah R5-920 Medicine (General) Mosquito-borne diseases are increasing every year and causing million deaths worldwide. The diseases are transmitted from the bite of an infected mosquito. Thus, it requires effective control measures to reduce the transmission rate, and one of the control strategies is using larvicide such as temephos. Currently, the carrier materials used in the larvicide formulation raised environmental concerns due to their nonrenewable sources. The cellulose nanofiber from kenaf is seen as a sustainable replacement for larvicide carrier. The objectives of this study are to determine the capability of kenaf cellulose nanofiber (KCNF) to disperse and load temephos, the stability of KCNF impregnated with temephos (KCNF+T) in retaining temephos, the acute systemic toxicity of KCNF and KNCF+T in mammals, the acute ecotoxicity of KCNF in the aquatic organisms and the bioefficacy of KCNF+T as a larvicide carrier against Aedes aegypti mosquito larvae. The capability of KCNF to disperse is determined using the method adopted from OECD TG 318 and loading capability is evaluated using various water volume loaded on the dry KCNF. The amount of temephos impregnated on KCNF is quantified by HPLC analysis. KCNF is found to have high dispersion capability with more than 50 % dispersibility in six out of nine tested hydrochemical conditions and loading capability 6-fold of its mass. Amount of temephos impregnated on KCNF is found 1.94 % w/w reflecting 97 % impregnation efficacy. 2022-06 Thesis http://eprints.usm.my/59361/ http://eprints.usm.my/59361/1/HAZIRAH%20BINTI%20PENGIRAN%20-%20TESIS24.pdf application/pdf en public phd doctoral Universiti Sains Malaysia Institut Perubatan dan Pergigian Termaju
institution	Universiti Sains Malaysia
collection	USM Institutional Repository
language	English
topic	R5-920 Medicine (General)
spellingShingle	R5-920 Medicine (General) Pengiran, Hazirah Studies Of Capability, Stability, Toxicity And Bioefficacy Of Kenaf Based Cellulose Nanofiber As Larvicide Carrier For Mosquito Control
description	Mosquito-borne diseases are increasing every year and causing million deaths worldwide. The diseases are transmitted from the bite of an infected mosquito. Thus, it requires effective control measures to reduce the transmission rate, and one of the control strategies is using larvicide such as temephos. Currently, the carrier materials used in the larvicide formulation raised environmental concerns due to their nonrenewable sources. The cellulose nanofiber from kenaf is seen as a sustainable replacement for larvicide carrier. The objectives of this study are to determine the capability of kenaf cellulose nanofiber (KCNF) to disperse and load temephos, the stability of KCNF impregnated with temephos (KCNF+T) in retaining temephos, the acute systemic toxicity of KCNF and KNCF+T in mammals, the acute ecotoxicity of KCNF in the aquatic organisms and the bioefficacy of KCNF+T as a larvicide carrier against Aedes aegypti mosquito larvae. The capability of KCNF to disperse is determined using the method adopted from OECD TG 318 and loading capability is evaluated using various water volume loaded on the dry KCNF. The amount of temephos impregnated on KCNF is quantified by HPLC analysis. KCNF is found to have high dispersion capability with more than 50 % dispersibility in six out of nine tested hydrochemical conditions and loading capability 6-fold of its mass. Amount of temephos impregnated on KCNF is found 1.94 % w/w reflecting 97 % impregnation efficacy.
format	Thesis
qualification_name	Doctor of Philosophy (PhD.)
qualification_level	Doctorate
author	Pengiran, Hazirah
author_facet	Pengiran, Hazirah
author_sort	Pengiran, Hazirah
title	Studies Of Capability, Stability, Toxicity And Bioefficacy Of Kenaf Based Cellulose Nanofiber As Larvicide Carrier For Mosquito Control
title_short	Studies Of Capability, Stability, Toxicity And Bioefficacy Of Kenaf Based Cellulose Nanofiber As Larvicide Carrier For Mosquito Control
title_full	Studies Of Capability, Stability, Toxicity And Bioefficacy Of Kenaf Based Cellulose Nanofiber As Larvicide Carrier For Mosquito Control
title_fullStr	Studies Of Capability, Stability, Toxicity And Bioefficacy Of Kenaf Based Cellulose Nanofiber As Larvicide Carrier For Mosquito Control
title_full_unstemmed	Studies Of Capability, Stability, Toxicity And Bioefficacy Of Kenaf Based Cellulose Nanofiber As Larvicide Carrier For Mosquito Control
title_sort	studies of capability, stability, toxicity and bioefficacy of kenaf based cellulose nanofiber as larvicide carrier for mosquito control
granting_institution	Universiti Sains Malaysia
granting_department	Institut Perubatan dan Pergigian Termaju
publishDate	2022
url	http://eprints.usm.my/59361/1/HAZIRAH%20BINTI%20PENGIRAN%20-%20TESIS24.pdf
_version_	1783729540514709504

Studies Of Capability, Stability, Toxicity And Bioefficacy Of Kenaf Based Cellulose Nanofiber As Larvicide Carrier For Mosquito Control

Similar Items