Evaluation Of Toxicity, Pharmacokinetic And Clastogenicity Profile Of Ethyl 2-[4[(Piperidin-1-yl) Phenyl]-1h-benzimidazole-5-carboxylate (Bzd9l1), Novel Sirtuin Inhibitor

The mammalian sirtuins (SIRTs) have been linked to various diseases including cancer, diabetes, neurodegenerative and cardiovascular diseases. Thus, SIRTs are attractive targets for the development of pharmaceuticals. The lack of potential SIRT inhibitors in cancer clinical trials highlights the nee...

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Bibliographic Details
Main Author: Lee, Yeuan Ting
Format: Thesis
Language:English
Published: 2022
Subjects:
Online Access:http://eprints.usm.my/59372/1/LEE%20YEUAN%20TING%20-%20TESIS24.pdf
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