Comparison Of Eight Methods For Estimation Of Creatinine Clearance In Malaysia Patients With Unstable Renal Function

Unstable kidney function is a common complication in hospitalized patients and is associated with high mortality rate. Critically ill patients normally have fluctuating kidney function with serum creatinine changing from day to day. Creatinine clearance (Clcr) estimation is of great importance in da...

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Main Author:	Ng Yen, Ping
Format:	Thesis
Language:	English
Published:	2022
Subjects:	RS1-441 Pharmacy and materia medica
Online Access:	http://eprints.usm.my/59614/1/24%20Pages%20from%20NG%20YEN%20PING.pdf
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id	my-usm-ep.59614
record_format	uketd_dc
spelling	my-usm-ep.596142023-11-30T02:45:13Z Comparison Of Eight Methods For Estimation Of Creatinine Clearance In Malaysia Patients With Unstable Renal Function 2022-01 Ng Yen, Ping RS1-441 Pharmacy and materia medica Unstable kidney function is a common complication in hospitalized patients and is associated with high mortality rate. Critically ill patients normally have fluctuating kidney function with serum creatinine changing from day to day. Creatinine clearance (Clcr) estimation is of great importance in daily clinical practice among critically ill patients with unstable kidney function. The Cockcroft-Gault method remained the most widely used method to estimate kidney function and to guide drug dosage adjustment. The Cockcroft-Gault equation was derived from conditions in which the serum creatinine was at steady state and it is not designed for patients with unstable kidney function. This study aimed to analyze the discrepancies of estimated creatinine clearance computed by Cockcroft & Gault, MDRD, CKD-EPI, Jelliffe, modified Jelliffe, Chiou, Brater, and an empiric estimating equation (modified Cockcroft-Gault) equations with 24 hours urinary creatinine clearance (standard control) in critically ill and unstable kidney function patients from local Malaysian population. 2022-01 Thesis http://eprints.usm.my/59614/ http://eprints.usm.my/59614/1/24%20Pages%20from%20NG%20YEN%20PING.pdf application/pdf en public phd doctoral Perpustakaan Hamzah Sendut Pusat Pengajian Sains Farmasi
institution	Universiti Sains Malaysia
collection	USM Institutional Repository
language	English
topic	RS1-441 Pharmacy and materia medica
spellingShingle	RS1-441 Pharmacy and materia medica Ng Yen, Ping Comparison Of Eight Methods For Estimation Of Creatinine Clearance In Malaysia Patients With Unstable Renal Function
description	Unstable kidney function is a common complication in hospitalized patients and is associated with high mortality rate. Critically ill patients normally have fluctuating kidney function with serum creatinine changing from day to day. Creatinine clearance (Clcr) estimation is of great importance in daily clinical practice among critically ill patients with unstable kidney function. The Cockcroft-Gault method remained the most widely used method to estimate kidney function and to guide drug dosage adjustment. The Cockcroft-Gault equation was derived from conditions in which the serum creatinine was at steady state and it is not designed for patients with unstable kidney function. This study aimed to analyze the discrepancies of estimated creatinine clearance computed by Cockcroft & Gault, MDRD, CKD-EPI, Jelliffe, modified Jelliffe, Chiou, Brater, and an empiric estimating equation (modified Cockcroft-Gault) equations with 24 hours urinary creatinine clearance (standard control) in critically ill and unstable kidney function patients from local Malaysian population.
format	Thesis
qualification_name	Doctor of Philosophy (PhD.)
qualification_level	Doctorate
author	Ng Yen, Ping
author_facet	Ng Yen, Ping
author_sort	Ng Yen, Ping
title	Comparison Of Eight Methods For Estimation Of Creatinine Clearance In Malaysia Patients With Unstable Renal Function
title_short	Comparison Of Eight Methods For Estimation Of Creatinine Clearance In Malaysia Patients With Unstable Renal Function
title_full	Comparison Of Eight Methods For Estimation Of Creatinine Clearance In Malaysia Patients With Unstable Renal Function
title_fullStr	Comparison Of Eight Methods For Estimation Of Creatinine Clearance In Malaysia Patients With Unstable Renal Function
title_full_unstemmed	Comparison Of Eight Methods For Estimation Of Creatinine Clearance In Malaysia Patients With Unstable Renal Function
title_sort	comparison of eight methods for estimation of creatinine clearance in malaysia patients with unstable renal function
granting_institution	Perpustakaan Hamzah Sendut
granting_department	Pusat Pengajian Sains Farmasi
publishDate	2022
url	http://eprints.usm.my/59614/1/24%20Pages%20from%20NG%20YEN%20PING.pdf
_version_	1794024027802566656

Comparison Of Eight Methods For Estimation Of Creatinine Clearance In Malaysia Patients With Unstable Renal Function

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