Phytochemical, Bioassay And In Silico Studies On Anti - Cholinesterase Activities Of Cassia Timoriensis Dc. And Cassia Grandis L.F.

Historically, Cassia species have been demonstrated to possess several biological activities. However, scientific research on Cassia timoriensis and Cassia grandis remains limited. In this study, the aim was to discover new cholinesterase (ChE) inhibitors to alleviate acetylcholine (ACh) depletion i...

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Main Author:	Al-Hawarri, Maram Basem Tawfiq
Format:	Thesis
Language:	English
Published:	2022
Subjects:	RS1-441 Pharmacy and materia medica
Online Access:	http://eprints.usm.my/59710/1/24%20Pages%20from%20MARAM%20BASEM%20TAWFIQ%20AL-HAWARRI%20-%20TESIS.pdf
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id	my-usm-ep.59710
record_format	uketd_dc
spelling	my-usm-ep.597102023-12-20T02:17:57Z Phytochemical, Bioassay And In Silico Studies On Anti - Cholinesterase Activities Of Cassia Timoriensis Dc. And Cassia Grandis L.F. 2022-09 Al-Hawarri, Maram Basem Tawfiq RS1-441 Pharmacy and materia medica Historically, Cassia species have been demonstrated to possess several biological activities. However, scientific research on Cassia timoriensis and Cassia grandis remains limited. In this study, the aim was to discover new cholinesterase (ChE) inhibitors to alleviate acetylcholine (ACh) depletion in Alzheimer’s disease (AD). Hence, acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) inhibitory potentials, radical scavenging ability, and anti-inflammatory properties of various extracts of C. timoriensis and C. grandis were carried out using Ellman’s assay, DPPH assay, and an albumin denaturation assay, respectively. 2022-09 Thesis http://eprints.usm.my/59710/ http://eprints.usm.my/59710/1/24%20Pages%20from%20MARAM%20BASEM%20TAWFIQ%20AL-HAWARRI%20-%20TESIS.pdf application/pdf en public phd doctoral Perpustakaan Hamzah Sendut Pusat Pengajian Sains Farmasi
institution	Universiti Sains Malaysia
collection	USM Institutional Repository
language	English
topic	RS1-441 Pharmacy and materia medica
spellingShingle	RS1-441 Pharmacy and materia medica Al-Hawarri, Maram Basem Tawfiq Phytochemical, Bioassay And In Silico Studies On Anti - Cholinesterase Activities Of Cassia Timoriensis Dc. And Cassia Grandis L.F.
description	Historically, Cassia species have been demonstrated to possess several biological activities. However, scientific research on Cassia timoriensis and Cassia grandis remains limited. In this study, the aim was to discover new cholinesterase (ChE) inhibitors to alleviate acetylcholine (ACh) depletion in Alzheimer’s disease (AD). Hence, acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) inhibitory potentials, radical scavenging ability, and anti-inflammatory properties of various extracts of C. timoriensis and C. grandis were carried out using Ellman’s assay, DPPH assay, and an albumin denaturation assay, respectively.
format	Thesis
qualification_name	Doctor of Philosophy (PhD.)
qualification_level	Doctorate
author	Al-Hawarri, Maram Basem Tawfiq
author_facet	Al-Hawarri, Maram Basem Tawfiq
author_sort	Al-Hawarri, Maram Basem Tawfiq
title	Phytochemical, Bioassay And In Silico Studies On Anti - Cholinesterase Activities Of Cassia Timoriensis Dc. And Cassia Grandis L.F.
title_short	Phytochemical, Bioassay And In Silico Studies On Anti - Cholinesterase Activities Of Cassia Timoriensis Dc. And Cassia Grandis L.F.
title_full	Phytochemical, Bioassay And In Silico Studies On Anti - Cholinesterase Activities Of Cassia Timoriensis Dc. And Cassia Grandis L.F.
title_fullStr	Phytochemical, Bioassay And In Silico Studies On Anti - Cholinesterase Activities Of Cassia Timoriensis Dc. And Cassia Grandis L.F.
title_full_unstemmed	Phytochemical, Bioassay And In Silico Studies On Anti - Cholinesterase Activities Of Cassia Timoriensis Dc. And Cassia Grandis L.F.
title_sort	phytochemical, bioassay and in silico studies on anti - cholinesterase activities of cassia timoriensis dc. and cassia grandis l.f.
granting_institution	Perpustakaan Hamzah Sendut
granting_department	Pusat Pengajian Sains Farmasi
publishDate	2022
url	http://eprints.usm.my/59710/1/24%20Pages%20from%20MARAM%20BASEM%20TAWFIQ%20AL-HAWARRI%20-%20TESIS.pdf
_version_	1794024040668594176

Phytochemical, Bioassay And In Silico Studies On Anti - Cholinesterase Activities Of Cassia Timoriensis Dc. And Cassia Grandis L.F.

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