Characterisation Of Bacteriocin-Like Inhibitory Substances Derived From Locally Isolated Lactobacillus Paracasei Fd1 And Its Synergic Impact With Antibiotics

The goal of this research is to minimise antibiotic use while also looking at the synergistic impact of antibiotics and BLIS produced by locally isolated lactic acid bacteria, Lactobacillus paracasei FD1, from fermented durian. Synergistic effect was combining BLIS, BLIS MIC, and BLIS IC50 with anti...

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Bibliographic Details
Main Author: Tang, Hock Wei
Format: Thesis
Language:English
Published: 2022
Subjects:
Online Access:http://eprints.usm.my/59749/1/Pages%20from%20TANG%20HOCK%20WEI%20-%20TESIS.pdf
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Summary:The goal of this research is to minimise antibiotic use while also looking at the synergistic impact of antibiotics and BLIS produced by locally isolated lactic acid bacteria, Lactobacillus paracasei FD1, from fermented durian. Synergistic effect was combining BLIS, BLIS MIC, and BLIS IC50 with antibiotics at working concentrations for antibiotics that show zero effectiveness against multidrug resistance, while BLIS, BLIS MIC, and BLIS IC50 combined with MIC and IC50 of antibiotics that show ability to inhibit multidrug resistance