Prevalence, Clinical Manifestations, Treatment Outcomes, Cost Of Treatment And Health Related Quality Of Life (Hrqol) Of Chronic Pulmonary Aspergillosis (Cpa) In A Tertiary Referral Hospital In Lahore, Pakistan

Chronic Pulmonary Aspergillosis is a chronic progressive infection that destroys lung tissue in non-immunocompromised patients. There has been a dearth of investigation on the CPA. Therefore, a two-phase retrospective and prospective study was conducted to assess the epidemiology, clinical manifesta...

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Main Author:	Akram, Waqas
Format:	Thesis
Language:	English
Published:	2023
Subjects:	RS1-441 Pharmacy and materia medica
Online Access:	http://eprints.usm.my/60354/1/WAQAS%20AKRAM%20-%20TESIS%20cut.pdf
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id	my-usm-ep.60354
record_format	uketd_dc
spelling	my-usm-ep.603542024-04-05T03:11:10Z Prevalence, Clinical Manifestations, Treatment Outcomes, Cost Of Treatment And Health Related Quality Of Life (Hrqol) Of Chronic Pulmonary Aspergillosis (Cpa) In A Tertiary Referral Hospital In Lahore, Pakistan 2023-07 Akram, Waqas RS1-441 Pharmacy and materia medica Chronic Pulmonary Aspergillosis is a chronic progressive infection that destroys lung tissue in non-immunocompromised patients. There has been a dearth of investigation on the CPA. Therefore, a two-phase retrospective and prospective study was conducted to assess the epidemiology, clinical manifestations, treatment outcomes, risk factors associated with the development, prolonged Length of Stay, mortality, direct cost of treatment, and Health Related Quality of Life of CPA patients attending Gulab Devi Chest Hospital, Lahore, Pakistan. During retrospective phase (2017-2019), a total of 44,028 respiratory patients were reviewed. CPA was observed in 248 (0.56 %) cases. The prevalence of CPA was 563/100,000. A total of 218 CPA patients were included in this phase. The most common phenotype of CPA was Simple Aspergilloma (56.0%) followed by Chronic Cavitary Pulmonary Aspergillosis (31.2%) and Sub Acute Invasive Aspergillosis (12.8%) respectively. The most common symptoms in the CPA patients were cough (95.0%), fatigue (92.7%), sputum production (90.4%), fever (85.8%), hemoptysis (59.6%), and weight loss (34.9%). Tuberculosis (62.8%), Non-Tuberculosis Mycobacteria (30.7%), and Diabetes Mellitus (29.8%) were the most common underlying diseases. After CPA was diagnosed, 2023-07 Thesis http://eprints.usm.my/60354/ http://eprints.usm.my/60354/1/WAQAS%20AKRAM%20-%20TESIS%20cut.pdf application/pdf en public phd doctoral Universiti Sains Malaysia Pusat Pengajian Sains Farmasi
institution	Universiti Sains Malaysia
collection	USM Institutional Repository
language	English
topic	RS1-441 Pharmacy and materia medica
spellingShingle	RS1-441 Pharmacy and materia medica Akram, Waqas Prevalence, Clinical Manifestations, Treatment Outcomes, Cost Of Treatment And Health Related Quality Of Life (Hrqol) Of Chronic Pulmonary Aspergillosis (Cpa) In A Tertiary Referral Hospital In Lahore, Pakistan
description	Chronic Pulmonary Aspergillosis is a chronic progressive infection that destroys lung tissue in non-immunocompromised patients. There has been a dearth of investigation on the CPA. Therefore, a two-phase retrospective and prospective study was conducted to assess the epidemiology, clinical manifestations, treatment outcomes, risk factors associated with the development, prolonged Length of Stay, mortality, direct cost of treatment, and Health Related Quality of Life of CPA patients attending Gulab Devi Chest Hospital, Lahore, Pakistan. During retrospective phase (2017-2019), a total of 44,028 respiratory patients were reviewed. CPA was observed in 248 (0.56 %) cases. The prevalence of CPA was 563/100,000. A total of 218 CPA patients were included in this phase. The most common phenotype of CPA was Simple Aspergilloma (56.0%) followed by Chronic Cavitary Pulmonary Aspergillosis (31.2%) and Sub Acute Invasive Aspergillosis (12.8%) respectively. The most common symptoms in the CPA patients were cough (95.0%), fatigue (92.7%), sputum production (90.4%), fever (85.8%), hemoptysis (59.6%), and weight loss (34.9%). Tuberculosis (62.8%), Non-Tuberculosis Mycobacteria (30.7%), and Diabetes Mellitus (29.8%) were the most common underlying diseases. After CPA was diagnosed,
format	Thesis
qualification_name	Doctor of Philosophy (PhD.)
qualification_level	Doctorate
author	Akram, Waqas
author_facet	Akram, Waqas
author_sort	Akram, Waqas
title	Prevalence, Clinical Manifestations, Treatment Outcomes, Cost Of Treatment And Health Related Quality Of Life (Hrqol) Of Chronic Pulmonary Aspergillosis (Cpa) In A Tertiary Referral Hospital In Lahore, Pakistan
title_short	Prevalence, Clinical Manifestations, Treatment Outcomes, Cost Of Treatment And Health Related Quality Of Life (Hrqol) Of Chronic Pulmonary Aspergillosis (Cpa) In A Tertiary Referral Hospital In Lahore, Pakistan
title_full	Prevalence, Clinical Manifestations, Treatment Outcomes, Cost Of Treatment And Health Related Quality Of Life (Hrqol) Of Chronic Pulmonary Aspergillosis (Cpa) In A Tertiary Referral Hospital In Lahore, Pakistan
title_fullStr	Prevalence, Clinical Manifestations, Treatment Outcomes, Cost Of Treatment And Health Related Quality Of Life (Hrqol) Of Chronic Pulmonary Aspergillosis (Cpa) In A Tertiary Referral Hospital In Lahore, Pakistan
title_full_unstemmed	Prevalence, Clinical Manifestations, Treatment Outcomes, Cost Of Treatment And Health Related Quality Of Life (Hrqol) Of Chronic Pulmonary Aspergillosis (Cpa) In A Tertiary Referral Hospital In Lahore, Pakistan
title_sort	prevalence, clinical manifestations, treatment outcomes, cost of treatment and health related quality of life (hrqol) of chronic pulmonary aspergillosis (cpa) in a tertiary referral hospital in lahore, pakistan
granting_institution	Universiti Sains Malaysia
granting_department	Pusat Pengajian Sains Farmasi
publishDate	2023
url	http://eprints.usm.my/60354/1/WAQAS%20AKRAM%20-%20TESIS%20cut.pdf
_version_	1804888919917985792

Prevalence, Clinical Manifestations, Treatment Outcomes, Cost Of Treatment And Health Related Quality Of Life (Hrqol) Of Chronic Pulmonary Aspergillosis (Cpa) In A Tertiary Referral Hospital In Lahore, Pakistan

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