Effects Of High Fiber Multigrain Supplementation On Clinical Disease Measures, Inflammatory Biomarkers, Nutritional Status And Quality Of Life Among Moderate To Severe Rheumatoid Arthritis Patients

Rheumatoid Arthritis (RA) is a chronic inflammatory, autoimmune rheumatic disease, resulting in progressive joint inflammation and destruction attributed by a combination of genetic and environmental factor. The current RA drugs may help slow the disease's progression, but they may cause side e...

Full description

Saved in:

Bibliographic Details
Main Author:	Abdul Latif, Farzana Athirah
Format:	Thesis
Language:	English
Published:	2022
Subjects:	T11.95-12.5 Industrial directories
Online Access:	http://eprints.usm.my/60521/1/FARZANA%20ATHIRAH%20BINTI%20ABDUL%20LATIF%20-%20TESIS%20cut.pdf
Tags:	Add Tag No Tags, Be the first to tag this record!

id	my-usm-ep.60521
record_format	uketd_dc
spelling	my-usm-ep.605212024-05-03T04:01:24Z Effects Of High Fiber Multigrain Supplementation On Clinical Disease Measures, Inflammatory Biomarkers, Nutritional Status And Quality Of Life Among Moderate To Severe Rheumatoid Arthritis Patients 2022-10 Abdul Latif, Farzana Athirah T11.95-12.5 Industrial directories Rheumatoid Arthritis (RA) is a chronic inflammatory, autoimmune rheumatic disease, resulting in progressive joint inflammation and destruction attributed by a combination of genetic and environmental factor. The current RA drugs may help slow the disease's progression, but they may cause side effects. Due to the potential side effects, many RA patients swifted to other alternative remedies. Dietary nutritional components have been demonstrated to influence inflammation, oxidative stress, and disease progression. With the aforementioned, this study is aimed to evaluate the effect of high fiber multigrain supplementation on (1) clinical disease symptoms, (2) inflammation status, (3) antioxidant and oxidative stress level (4) nutritional status, quality of life and functionality in RA patients. Fifty-one RA patients were recruited from Rheumatology Unit, Hospital Universiti Sains Malaysia, and randomly assigned into either high fiber multigrain supplement (n=25; standard rheumatic medication + 80g/d multigrain) or control (n=26; standard rheumatic medication) groups for 12 weeks. Clinical assessments were improved significantly in the supplement group; as evident by reductions in disease activity score (DAS 28) (p<0.05), morning stiffness rating scale (p<0.01), joint scale (p<0.05) and pain scale (p<0.01). 2022-10 Thesis http://eprints.usm.my/60521/ http://eprints.usm.my/60521/1/FARZANA%20ATHIRAH%20BINTI%20ABDUL%20LATIF%20-%20TESIS%20cut.pdf application/pdf en public phd doctoral Universiti Sains Malaysia Pusat Pengajian Teknologi Industri
institution	Universiti Sains Malaysia
collection	USM Institutional Repository
language	English
topic	T11.95-12.5 Industrial directories
spellingShingle	T11.95-12.5 Industrial directories Abdul Latif, Farzana Athirah Effects Of High Fiber Multigrain Supplementation On Clinical Disease Measures, Inflammatory Biomarkers, Nutritional Status And Quality Of Life Among Moderate To Severe Rheumatoid Arthritis Patients
description	Rheumatoid Arthritis (RA) is a chronic inflammatory, autoimmune rheumatic disease, resulting in progressive joint inflammation and destruction attributed by a combination of genetic and environmental factor. The current RA drugs may help slow the disease's progression, but they may cause side effects. Due to the potential side effects, many RA patients swifted to other alternative remedies. Dietary nutritional components have been demonstrated to influence inflammation, oxidative stress, and disease progression. With the aforementioned, this study is aimed to evaluate the effect of high fiber multigrain supplementation on (1) clinical disease symptoms, (2) inflammation status, (3) antioxidant and oxidative stress level (4) nutritional status, quality of life and functionality in RA patients. Fifty-one RA patients were recruited from Rheumatology Unit, Hospital Universiti Sains Malaysia, and randomly assigned into either high fiber multigrain supplement (n=25; standard rheumatic medication + 80g/d multigrain) or control (n=26; standard rheumatic medication) groups for 12 weeks. Clinical assessments were improved significantly in the supplement group; as evident by reductions in disease activity score (DAS 28) (p<0.05), morning stiffness rating scale (p<0.01), joint scale (p<0.05) and pain scale (p<0.01).
format	Thesis
qualification_name	Doctor of Philosophy (PhD.)
qualification_level	Doctorate
author	Abdul Latif, Farzana Athirah
author_facet	Abdul Latif, Farzana Athirah
author_sort	Abdul Latif, Farzana Athirah
title	Effects Of High Fiber Multigrain Supplementation On Clinical Disease Measures, Inflammatory Biomarkers, Nutritional Status And Quality Of Life Among Moderate To Severe Rheumatoid Arthritis Patients
title_short	Effects Of High Fiber Multigrain Supplementation On Clinical Disease Measures, Inflammatory Biomarkers, Nutritional Status And Quality Of Life Among Moderate To Severe Rheumatoid Arthritis Patients
title_full	Effects Of High Fiber Multigrain Supplementation On Clinical Disease Measures, Inflammatory Biomarkers, Nutritional Status And Quality Of Life Among Moderate To Severe Rheumatoid Arthritis Patients
title_fullStr	Effects Of High Fiber Multigrain Supplementation On Clinical Disease Measures, Inflammatory Biomarkers, Nutritional Status And Quality Of Life Among Moderate To Severe Rheumatoid Arthritis Patients
title_full_unstemmed	Effects Of High Fiber Multigrain Supplementation On Clinical Disease Measures, Inflammatory Biomarkers, Nutritional Status And Quality Of Life Among Moderate To Severe Rheumatoid Arthritis Patients
title_sort	effects of high fiber multigrain supplementation on clinical disease measures, inflammatory biomarkers, nutritional status and quality of life among moderate to severe rheumatoid arthritis patients
granting_institution	Universiti Sains Malaysia
granting_department	Pusat Pengajian Teknologi Industri
publishDate	2022
url	http://eprints.usm.my/60521/1/FARZANA%20ATHIRAH%20BINTI%20ABDUL%20LATIF%20-%20TESIS%20cut.pdf
_version_	1804888955099807744

Effects Of High Fiber Multigrain Supplementation On Clinical Disease Measures, Inflammatory Biomarkers, Nutritional Status And Quality Of Life Among Moderate To Severe Rheumatoid Arthritis Patients

Similar Items