Tubulin-Targeting Activity Of Phytoestrogens Present In Cosmos Caudatus Aqueous Extract Against Colorectal Cancer Cell Line Ht-29

Tubulin-Targeting Activity Of Phytoestrogens Present In Cosmos Caudatus Aqueous Extract Against Colorectal Cancer Cell Line Ht-29

Cosmos caudatus (C. caudatus) is a medicinal plant in Southeast Asia that contains phytoestrogens, sesquiterpene lactones and essential micronutrients. Phytoestrogens have been reported to possess pharmacological properties including anticancer activity. In this study we aimed to investigate tubulin...

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Main Author: Xu, Fan
Format: Thesis
Language:English
Published: 2023
Subjects:
R5-920 Medicine (General)
Online Access:http://eprints.usm.my/60585/1/Pages%20from%20XU%20FAN%20-%20TESIS.pdf
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spelling my-usm-ep.605852024-05-08T07:06:19Z Tubulin-Targeting Activity Of Phytoestrogens Present In Cosmos Caudatus Aqueous Extract Against Colorectal Cancer Cell Line Ht-29 2023-06 Xu, Fan R5-920 Medicine (General) Cosmos caudatus (C. caudatus) is a medicinal plant in Southeast Asia that contains phytoestrogens, sesquiterpene lactones and essential micronutrients. Phytoestrogens have been reported to possess pharmacological properties including anticancer activity. In this study we aimed to investigate tubulin-targeted activity of main phytoestrogens present in C. caudatus along with C. caudatus aqueous extract in colorectal cancer cell line HT-29. C. caudatus aqueous extract, kaempferol and quercetin were used to treat HT-29 cells for 24, 48 and 72 hours in 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay to evaluate the effects of the treatments on cell viability. 2023-06 Thesis http://eprints.usm.my/60585/ http://eprints.usm.my/60585/1/Pages%20from%20XU%20FAN%20-%20TESIS.pdf application/pdf en public masters Universiti Sains Malaysia Institut Perubatan & Pergigian Termaju (Advanced Medical & Dental Institute (AMDI)
institution Universiti Sains Malaysia
collection USM Institutional Repository
language English
topic R5-920 Medicine (General)
spellingShingle R5-920 Medicine (General)
Xu, Fan
Tubulin-Targeting Activity Of Phytoestrogens Present In Cosmos Caudatus Aqueous Extract Against Colorectal Cancer Cell Line Ht-29
description Cosmos caudatus (C. caudatus) is a medicinal plant in Southeast Asia that contains phytoestrogens, sesquiterpene lactones and essential micronutrients. Phytoestrogens have been reported to possess pharmacological properties including anticancer activity. In this study we aimed to investigate tubulin-targeted activity of main phytoestrogens present in C. caudatus along with C. caudatus aqueous extract in colorectal cancer cell line HT-29. C. caudatus aqueous extract, kaempferol and quercetin were used to treat HT-29 cells for 24, 48 and 72 hours in 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay to evaluate the effects of the treatments on cell viability.
format Thesis
qualification_level Master's degree
author Xu, Fan
author_facet Xu, Fan
author_sort Xu, Fan
title Tubulin-Targeting Activity Of Phytoestrogens Present In Cosmos Caudatus Aqueous Extract Against Colorectal Cancer Cell Line Ht-29
title_short Tubulin-Targeting Activity Of Phytoestrogens Present In Cosmos Caudatus Aqueous Extract Against Colorectal Cancer Cell Line Ht-29
title_full Tubulin-Targeting Activity Of Phytoestrogens Present In Cosmos Caudatus Aqueous Extract Against Colorectal Cancer Cell Line Ht-29
title_fullStr Tubulin-Targeting Activity Of Phytoestrogens Present In Cosmos Caudatus Aqueous Extract Against Colorectal Cancer Cell Line Ht-29
title_full_unstemmed Tubulin-Targeting Activity Of Phytoestrogens Present In Cosmos Caudatus Aqueous Extract Against Colorectal Cancer Cell Line Ht-29
title_sort tubulin-targeting activity of phytoestrogens present in cosmos caudatus aqueous extract against colorectal cancer cell line ht-29
granting_institution Universiti Sains Malaysia
granting_department Institut Perubatan & Pergigian Termaju (Advanced Medical & Dental Institute (AMDI)
publishDate 2023
url http://eprints.usm.my/60585/1/Pages%20from%20XU%20FAN%20-%20TESIS.pdf
_version_ 1804888968856076288

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