Isolation And Characterization Of Aptamers Against Leptospira Lipl32

In this study, both DNA and RNA aptamers were developed against LipL32. LepRapt-11 was shown to be the most potent RNA aptamer, with dissociation constant and limit of detection of 350 ± 47.45 and 100 nM as determined by direct Enzyme-linked Aptasorbent Assay (ELASA), respectively.

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Main Author: Yeoh, Tzi Shien
Format: Thesis
Language:English
Published: 2023
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Online Access:http://eprints.usm.my/60592/1/Pages%20from%20YEOH%20TZI%20SHIEN%20-%20TESIS.pdf
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spelling my-usm-ep.605922024-05-08T07:21:08Z Isolation And Characterization Of Aptamers Against Leptospira Lipl32 2023-06 Yeoh, Tzi Shien R5-920 Medicine (General) In this study, both DNA and RNA aptamers were developed against LipL32. LepRapt-11 was shown to be the most potent RNA aptamer, with dissociation constant and limit of detection of 350 ± 47.45 and 100 nM as determined by direct Enzyme-linked Aptasorbent Assay (ELASA), respectively. 2023-06 Thesis http://eprints.usm.my/60592/ http://eprints.usm.my/60592/1/Pages%20from%20YEOH%20TZI%20SHIEN%20-%20TESIS.pdf application/pdf en public phd doctoral Universiti Sains Malaysia Institut Perubatan & Pergigian Termaju (Advanced Medical & Dental Institute (AMDI)
institution Universiti Sains Malaysia
collection USM Institutional Repository
language English
topic R5-920 Medicine (General)
spellingShingle R5-920 Medicine (General)
Yeoh, Tzi Shien
Isolation And Characterization Of Aptamers Against Leptospira Lipl32
description In this study, both DNA and RNA aptamers were developed against LipL32. LepRapt-11 was shown to be the most potent RNA aptamer, with dissociation constant and limit of detection of 350 ± 47.45 and 100 nM as determined by direct Enzyme-linked Aptasorbent Assay (ELASA), respectively.
format Thesis
qualification_name Doctor of Philosophy (PhD.)
qualification_level Doctorate
author Yeoh, Tzi Shien
author_facet Yeoh, Tzi Shien
author_sort Yeoh, Tzi Shien
title Isolation And Characterization Of Aptamers Against Leptospira Lipl32
title_short Isolation And Characterization Of Aptamers Against Leptospira Lipl32
title_full Isolation And Characterization Of Aptamers Against Leptospira Lipl32
title_fullStr Isolation And Characterization Of Aptamers Against Leptospira Lipl32
title_full_unstemmed Isolation And Characterization Of Aptamers Against Leptospira Lipl32
title_sort isolation and characterization of aptamers against leptospira lipl32
granting_institution Universiti Sains Malaysia
granting_department Institut Perubatan & Pergigian Termaju (Advanced Medical & Dental Institute (AMDI)
publishDate 2023
url http://eprints.usm.my/60592/1/Pages%20from%20YEOH%20TZI%20SHIEN%20-%20TESIS.pdf
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