Evaluation the effect of acitretin on ocular surface parameters in psoriatic vulgaris patients

Objective: To evaluate the effect of oral acitretin on ocular surface parameters which are, time of tear film to loss it integrity (by Tear Break up Time (TBUT)), production of tears by lacrimal gland (by Schirmer test), and score for Ocular Surface Disease Index (OSDI) in psoriatic vulgaris patient...

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Main Author:	Shariff, Saidatulakma
Format:	Thesis
Language:	English
Published:	2021
Subjects:	R Medicine RE Ophthalmology
Online Access:	http://eprints.usm.my/60669/1/SAIDATULAKMA%20BT%20SHARIFF-E.pdf
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id	my-usm-ep.60669
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spelling	my-usm-ep.606692024-07-17T00:46:50Z Evaluation the effect of acitretin on ocular surface parameters in psoriatic vulgaris patients 2021 Shariff, Saidatulakma R Medicine RE Ophthalmology Objective: To evaluate the effect of oral acitretin on ocular surface parameters which are, time of tear film to loss it integrity (by Tear Break up Time (TBUT)), production of tears by lacrimal gland (by Schirmer test), and score for Ocular Surface Disease Index (OSDI) in psoriatic vulgaris patients. Design: A prospective analysis of 29 patients with psoriasis vulgaris who need step up treatment to oral acitretin. Outcome measures included patients’ demographic data, types and duration of previous treatment for psoriasis received before, tear break-up time (TBUT), Schirmers’ test, and Ocular Surface Disease Index (OSDI) at baseline, 3 months and 6 months of treatment. Result: : No statistically significant changes were found in mean for TBUT, Schirmers test and OSDI in psoriasis vulgaris patient treated with oral acitretin for 6 months durations. Conclusion: Ocular surface integrity and tear film are not affected by 6 months therapy with oral acitretin in psoriasis vulgaris patients. 2021 Thesis http://eprints.usm.my/60669/ http://eprints.usm.my/60669/1/SAIDATULAKMA%20BT%20SHARIFF-E.pdf application/pdf en public masters Universiti Sains Malaysia Pusat Pengajian Sains Perubatan
institution	Universiti Sains Malaysia
collection	USM Institutional Repository
language	English
topic	R Medicine RE Ophthalmology
spellingShingle	R Medicine RE Ophthalmology Shariff, Saidatulakma Evaluation the effect of acitretin on ocular surface parameters in psoriatic vulgaris patients
description	Objective: To evaluate the effect of oral acitretin on ocular surface parameters which are, time of tear film to loss it integrity (by Tear Break up Time (TBUT)), production of tears by lacrimal gland (by Schirmer test), and score for Ocular Surface Disease Index (OSDI) in psoriatic vulgaris patients. Design: A prospective analysis of 29 patients with psoriasis vulgaris who need step up treatment to oral acitretin. Outcome measures included patients’ demographic data, types and duration of previous treatment for psoriasis received before, tear break-up time (TBUT), Schirmers’ test, and Ocular Surface Disease Index (OSDI) at baseline, 3 months and 6 months of treatment. Result: : No statistically significant changes were found in mean for TBUT, Schirmers test and OSDI in psoriasis vulgaris patient treated with oral acitretin for 6 months durations. Conclusion: Ocular surface integrity and tear film are not affected by 6 months therapy with oral acitretin in psoriasis vulgaris patients.
format	Thesis
qualification_level	Master's degree
author	Shariff, Saidatulakma
author_facet	Shariff, Saidatulakma
author_sort	Shariff, Saidatulakma
title	Evaluation the effect of acitretin on ocular surface parameters in psoriatic vulgaris patients
title_short	Evaluation the effect of acitretin on ocular surface parameters in psoriatic vulgaris patients
title_full	Evaluation the effect of acitretin on ocular surface parameters in psoriatic vulgaris patients
title_fullStr	Evaluation the effect of acitretin on ocular surface parameters in psoriatic vulgaris patients
title_full_unstemmed	Evaluation the effect of acitretin on ocular surface parameters in psoriatic vulgaris patients
title_sort	evaluation the effect of acitretin on ocular surface parameters in psoriatic vulgaris patients
granting_institution	Universiti Sains Malaysia
granting_department	Pusat Pengajian Sains Perubatan
publishDate	2021
url	http://eprints.usm.my/60669/1/SAIDATULAKMA%20BT%20SHARIFF-E.pdf
_version_	1804888982422552576

Evaluation the effect of acitretin on ocular surface parameters in psoriatic vulgaris patients

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