Ocular surface disorders and its associated factors among Intensive Care Unit patients

Introduction Patients in Intensive Care Unit are at increased risk of ocular surface disorders. Objective To determine the prevalence and its associated factors of ocular surface disorders in intensive care units. Methodology A cross sectional study was conducted from November 2020 until December...

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Main Author:	Hamid, Abbas Abd
Format:	Thesis
Language:	English
Published:	2022
Subjects:	R Medicine RE Ophthalmology
Online Access:	http://eprints.usm.my/60694/1/Abbas%20Abd%20Hamid-E.pdf
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spelling	my-usm-ep.606942024-07-17T00:53:05Z Ocular surface disorders and its associated factors among Intensive Care Unit patients 2022 Hamid, Abbas Abd R Medicine RE Ophthalmology Introduction Patients in Intensive Care Unit are at increased risk of ocular surface disorders. Objective To determine the prevalence and its associated factors of ocular surface disorders in intensive care units. Methodology A cross sectional study was conducted from November 2020 until December 2021 involving 166 patients in Intensive Care Unit, Hospital Selayang and Hospital Universiti Sains Malaysia. Exclusion criteria includes facial trauma involving orbital region, usage of topical medication and any pre-existing anterior segment ocular pathologies. Diagnosis made based on clinical assessments from tear break up time, corneal fluorescein stain and Schirmer’s test. Factors related to ocular surface disorders were assessed. Statistical analysis of simple and multiple logistic regression was performed using SPSS Inc version 26. Result A total of 166 patients were enrolled in this study. The mean age was 51.8 ± 14.32. The mean length of stay in the ICU was 11.5 ± 9.31 days. One hundred and thirty-five patients (81%) required ventilation, 114 (68.7%) required sedation and 67 (40.4%) required inotropes. Lagophthalmos was identified in 49 patients (29.5%). The prevalence of ocular surface disorders in the Intensive Care Unit patients was 63.3%. The following odds ratios (95% confidence intervals) for ocular surface disorders were estimated using the multiple logistic regression model: female: 5.97 (1.18, 30.22) and length of ICU stay: 2.58. (1.84, 33.63). Conclusion Ocular surface disorders are common in Intensive Care Unit patients. The prevalence is 63.3%. The most important associated risk factors that predispose to ocular surface disease were female gender and length of Intensive Care Unit hospitalisation. 2022 Thesis http://eprints.usm.my/60694/ http://eprints.usm.my/60694/1/Abbas%20Abd%20Hamid-E.pdf application/pdf en public masters Universiti Sains Malaysia Pusat Pengajian Sains Perubatan
institution	Universiti Sains Malaysia
collection	USM Institutional Repository
language	English
topic	R Medicine RE Ophthalmology
spellingShingle	R Medicine RE Ophthalmology Hamid, Abbas Abd Ocular surface disorders and its associated factors among Intensive Care Unit patients
description	Introduction Patients in Intensive Care Unit are at increased risk of ocular surface disorders. Objective To determine the prevalence and its associated factors of ocular surface disorders in intensive care units. Methodology A cross sectional study was conducted from November 2020 until December 2021 involving 166 patients in Intensive Care Unit, Hospital Selayang and Hospital Universiti Sains Malaysia. Exclusion criteria includes facial trauma involving orbital region, usage of topical medication and any pre-existing anterior segment ocular pathologies. Diagnosis made based on clinical assessments from tear break up time, corneal fluorescein stain and Schirmer’s test. Factors related to ocular surface disorders were assessed. Statistical analysis of simple and multiple logistic regression was performed using SPSS Inc version 26. Result A total of 166 patients were enrolled in this study. The mean age was 51.8 ± 14.32. The mean length of stay in the ICU was 11.5 ± 9.31 days. One hundred and thirty-five patients (81%) required ventilation, 114 (68.7%) required sedation and 67 (40.4%) required inotropes. Lagophthalmos was identified in 49 patients (29.5%). The prevalence of ocular surface disorders in the Intensive Care Unit patients was 63.3%. The following odds ratios (95% confidence intervals) for ocular surface disorders were estimated using the multiple logistic regression model: female: 5.97 (1.18, 30.22) and length of ICU stay: 2.58. (1.84, 33.63). Conclusion Ocular surface disorders are common in Intensive Care Unit patients. The prevalence is 63.3%. The most important associated risk factors that predispose to ocular surface disease were female gender and length of Intensive Care Unit hospitalisation.
format	Thesis
qualification_level	Master's degree
author	Hamid, Abbas Abd
author_facet	Hamid, Abbas Abd
author_sort	Hamid, Abbas Abd
title	Ocular surface disorders and its associated factors among Intensive Care Unit patients
title_short	Ocular surface disorders and its associated factors among Intensive Care Unit patients
title_full	Ocular surface disorders and its associated factors among Intensive Care Unit patients
title_fullStr	Ocular surface disorders and its associated factors among Intensive Care Unit patients
title_full_unstemmed	Ocular surface disorders and its associated factors among Intensive Care Unit patients
title_sort	ocular surface disorders and its associated factors among intensive care unit patients
granting_institution	Universiti Sains Malaysia
granting_department	Pusat Pengajian Sains Perubatan
publishDate	2022
url	http://eprints.usm.my/60694/1/Abbas%20Abd%20Hamid-E.pdf
_version_	1804888987441037312

Ocular surface disorders and its associated factors among Intensive Care Unit patients

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