Dose Verification Of Brass Mesh Bolus For Contralateral Breast Post-mastectomy In Three-dimensional Conformal Radiotherapy Technique

Post mastectomy radiation therapy (PMRT) prescribed to patient that undergo breast mastectomy. With the bolus application in PMRT, it has shown few limitations whereby current water equivalent bolus (WEB) unable to conform irregular surface consistently. Besides that, dose inhomogeneity arises in co...

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Main Author: Buang, Sakinah
Format: Thesis
Language:English
Published: 2023
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Online Access:http://eprints.usm.my/60730/1/SAKINAH%20BINTI%20BUANG%20-%20TESIS24.pdf
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spelling my-usm-ep.607302024-06-20T03:36:10Z Dose Verification Of Brass Mesh Bolus For Contralateral Breast Post-mastectomy In Three-dimensional Conformal Radiotherapy Technique 2023-09 Buang, Sakinah QC1 Physics (General) Post mastectomy radiation therapy (PMRT) prescribed to patient that undergo breast mastectomy. With the bolus application in PMRT, it has shown few limitations whereby current water equivalent bolus (WEB) unable to conform irregular surface consistently. Besides that, dose inhomogeneity arises in contralateral breast (CB) and organ at risk (OAR) during PMRT. It is established that brass mesh bolus (BMB) has potential in conforming irregular surface with the aim to treat chest wall site in delivering maximum dose and sparing OAR. This study aims to determine the feasibility of BMB as an alternative to bolus and to verify dose received by CB and target breast with application of BMB in 3-dimensional conformal radiation therapy (3DCRT). This study are designed based on three main parts ; firstly is to characterize dosimeters (Ludlum detector, ionization chamber and nanoDotTM) based on Cobalt-6o and 6-MV photon energy; secondly is to measure the radiological, physical and dosimetric properties of BMB by measuring the density using three methodologies (Image-J analysis, conventional density and CT analysis), mass attenuation coefficient, mass energy absorption coefficient and percentage depth dose (PDD) ; and lastly is to verify the radiotherapy treatment with the BMB to the PMRT heterogenous phantom by 3DCRT. Statistical analysis evaluation in accordance with the international standard was applied. The results revealed that all dosimeters have high linearity with acceptable traceability 2023-09 Thesis http://eprints.usm.my/60730/ http://eprints.usm.my/60730/1/SAKINAH%20BINTI%20BUANG%20-%20TESIS24.pdf application/pdf en public masters Universiti Sains Malaysia Pusat Pengajian Sains Fizik
institution Universiti Sains Malaysia
collection USM Institutional Repository
language English
topic QC1 Physics (General)
spellingShingle QC1 Physics (General)
Buang, Sakinah
Dose Verification Of Brass Mesh Bolus For Contralateral Breast Post-mastectomy In Three-dimensional Conformal Radiotherapy Technique
description Post mastectomy radiation therapy (PMRT) prescribed to patient that undergo breast mastectomy. With the bolus application in PMRT, it has shown few limitations whereby current water equivalent bolus (WEB) unable to conform irregular surface consistently. Besides that, dose inhomogeneity arises in contralateral breast (CB) and organ at risk (OAR) during PMRT. It is established that brass mesh bolus (BMB) has potential in conforming irregular surface with the aim to treat chest wall site in delivering maximum dose and sparing OAR. This study aims to determine the feasibility of BMB as an alternative to bolus and to verify dose received by CB and target breast with application of BMB in 3-dimensional conformal radiation therapy (3DCRT). This study are designed based on three main parts ; firstly is to characterize dosimeters (Ludlum detector, ionization chamber and nanoDotTM) based on Cobalt-6o and 6-MV photon energy; secondly is to measure the radiological, physical and dosimetric properties of BMB by measuring the density using three methodologies (Image-J analysis, conventional density and CT analysis), mass attenuation coefficient, mass energy absorption coefficient and percentage depth dose (PDD) ; and lastly is to verify the radiotherapy treatment with the BMB to the PMRT heterogenous phantom by 3DCRT. Statistical analysis evaluation in accordance with the international standard was applied. The results revealed that all dosimeters have high linearity with acceptable traceability
format Thesis
qualification_level Master's degree
author Buang, Sakinah
author_facet Buang, Sakinah
author_sort Buang, Sakinah
title Dose Verification Of Brass Mesh Bolus For Contralateral Breast Post-mastectomy In Three-dimensional Conformal Radiotherapy Technique
title_short Dose Verification Of Brass Mesh Bolus For Contralateral Breast Post-mastectomy In Three-dimensional Conformal Radiotherapy Technique
title_full Dose Verification Of Brass Mesh Bolus For Contralateral Breast Post-mastectomy In Three-dimensional Conformal Radiotherapy Technique
title_fullStr Dose Verification Of Brass Mesh Bolus For Contralateral Breast Post-mastectomy In Three-dimensional Conformal Radiotherapy Technique
title_full_unstemmed Dose Verification Of Brass Mesh Bolus For Contralateral Breast Post-mastectomy In Three-dimensional Conformal Radiotherapy Technique
title_sort dose verification of brass mesh bolus for contralateral breast post-mastectomy in three-dimensional conformal radiotherapy technique
granting_institution Universiti Sains Malaysia
granting_department Pusat Pengajian Sains Fizik
publishDate 2023
url http://eprints.usm.my/60730/1/SAKINAH%20BINTI%20BUANG%20-%20TESIS24.pdf
_version_ 1804888990951669760