An assessment of optic nerve parameters in Malay normal tension glaucoma and Primary open angle glaucoma patients

The recent availability of retinal imaging device plays an important role to differentiate the appearance of optic nerve in normal tension glaucoma (NTG) and primary open angle glaucoma (POAG) patients. There no published literature of these two group of glaucoma in patients of Malay ethnicity, o...

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Main Author:	Rahim, Adlina Abdul
Format:	Thesis
Language:	English
Published:	2012
Subjects:	R Medicine (General)
Online Access:	http://eprints.usm.my/60946/1/DR%20ADLINA%20BINTI%20ABDUL%20RAHIM%20-%20%20e.pdf
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spelling	my-usm-ep.609462024-08-14T03:01:37Z An assessment of optic nerve parameters in Malay normal tension glaucoma and Primary open angle glaucoma patients 2012 Rahim, Adlina Abdul R Medicine (General) The recent availability of retinal imaging device plays an important role to differentiate the appearance of optic nerve in normal tension glaucoma (NTG) and primary open angle glaucoma (POAG) patients. There no published literature of these two group of glaucoma in patients of Malay ethnicity, or even those who are living in South East Asian areas. To compare optic nerve head parameters among Malay NTG and POAG patients using HR.T III analysis. A comparative cross sectional study was carried out from November 2010 till February 2012 in two hospitals with availability of glaucoma service. A total of 154 eyes of 154 Malay patients were included in this study; 32 NTG patients, 45 POAG patients and 77 control group. All participants underwent a thorough ocular examination including visual acuity, subjective refraction, anterior segment and fundus examinations, Humphrey visual field 24-2, intraocular pressure measurement, gonioscopy examination and fundus photography. An assessment of optic nerve head parameters was conducted using FIRT III by an identified masked investigator in each hospital. Comparison of these two glaucoma groups was further analyzed according to the appearance on cup disc ratio on clinical assessment and AGIS scoring system. Both glaucoma groups had notably larger discs, larger cupping, smaller retinal rims area and thinner nerve fiber layers when compared to the control group (p<0.05). NTG patients revealed larger disc and cup areas when compared to the POAG patients (the mean (SD) for disc area was 2.65 (0.41) mm2 NTG group, and 2.40 (0.36) mm2 in POAG group, p = 0.006; the mean cup area (SD) of NTG patients was 1.54 (0.43) mm2 and 1.32 (0.40) mm2 in POAG group, p = 0.027). This observation was also parallel when they were further analyzed according to the severity of glaucoma in both studied groups. The optic nerve head parameters are significantly different in Malay NTG and POAG patients when compared to healthy individuals. Disc and cup areas are significantly larger in Malay NTG compared to POAG patients, while the other parameters are comparable in both groups. 2012 Thesis http://eprints.usm.my/60946/ http://eprints.usm.my/60946/1/DR%20ADLINA%20BINTI%20ABDUL%20RAHIM%20-%20%20e.pdf application/pdf en public masters Universiti Sains Malaysia Pusat Pengajian Sains Perubatan
institution	Universiti Sains Malaysia
collection	USM Institutional Repository
language	English
topic	R Medicine (General)
spellingShingle	R Medicine (General) Rahim, Adlina Abdul An assessment of optic nerve parameters in Malay normal tension glaucoma and Primary open angle glaucoma patients
description	The recent availability of retinal imaging device plays an important role to differentiate the appearance of optic nerve in normal tension glaucoma (NTG) and primary open angle glaucoma (POAG) patients. There no published literature of these two group of glaucoma in patients of Malay ethnicity, or even those who are living in South East Asian areas. To compare optic nerve head parameters among Malay NTG and POAG patients using HR.T III analysis. A comparative cross sectional study was carried out from November 2010 till February 2012 in two hospitals with availability of glaucoma service. A total of 154 eyes of 154 Malay patients were included in this study; 32 NTG patients, 45 POAG patients and 77 control group. All participants underwent a thorough ocular examination including visual acuity, subjective refraction, anterior segment and fundus examinations, Humphrey visual field 24-2, intraocular pressure measurement, gonioscopy examination and fundus photography. An assessment of optic nerve head parameters was conducted using FIRT III by an identified masked investigator in each hospital. Comparison of these two glaucoma groups was further analyzed according to the appearance on cup disc ratio on clinical assessment and AGIS scoring system. Both glaucoma groups had notably larger discs, larger cupping, smaller retinal rims area and thinner nerve fiber layers when compared to the control group (p<0.05). NTG patients revealed larger disc and cup areas when compared to the POAG patients (the mean (SD) for disc area was 2.65 (0.41) mm2 NTG group, and 2.40 (0.36) mm2 in POAG group, p = 0.006; the mean cup area (SD) of NTG patients was 1.54 (0.43) mm2 and 1.32 (0.40) mm2 in POAG group, p = 0.027). This observation was also parallel when they were further analyzed according to the severity of glaucoma in both studied groups. The optic nerve head parameters are significantly different in Malay NTG and POAG patients when compared to healthy individuals. Disc and cup areas are significantly larger in Malay NTG compared to POAG patients, while the other parameters are comparable in both groups.
format	Thesis
qualification_level	Master's degree
author	Rahim, Adlina Abdul
author_facet	Rahim, Adlina Abdul
author_sort	Rahim, Adlina Abdul
title	An assessment of optic nerve parameters in Malay normal tension glaucoma and Primary open angle glaucoma patients
title_short	An assessment of optic nerve parameters in Malay normal tension glaucoma and Primary open angle glaucoma patients
title_full	An assessment of optic nerve parameters in Malay normal tension glaucoma and Primary open angle glaucoma patients
title_fullStr	An assessment of optic nerve parameters in Malay normal tension glaucoma and Primary open angle glaucoma patients
title_full_unstemmed	An assessment of optic nerve parameters in Malay normal tension glaucoma and Primary open angle glaucoma patients
title_sort	assessment of optic nerve parameters in malay normal tension glaucoma and primary open angle glaucoma patients
granting_institution	Universiti Sains Malaysia
granting_department	Pusat Pengajian Sains Perubatan
publishDate	2012
url	http://eprints.usm.my/60946/1/DR%20ADLINA%20BINTI%20ABDUL%20RAHIM%20-%20%20e.pdf
_version_	1811772864650543104

An assessment of optic nerve parameters in Malay normal tension glaucoma and Primary open angle glaucoma patients

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