Optimizing The Production Of Short-Peptide Tagged Ss3A Recombinant Protein As A Potential Serological Biomarker For Strongyloidiasis

Strongyloides stercoralis is a human-pathogenic nematode with a unique ability to autoinfect causing a parasitic disease called strongyloidiasis. Although listed as one of the neglected tropical diseases by World Health Organisation (WHO), the infection has a worldwide distribution with approximatel...

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Main Author:	Hassan, Nur Hassanah Mohd
Format:	Thesis
Language:	English
Published:	2023
Subjects:	T1-995 Technology(General)
Online Access:	http://eprints.usm.my/61321/1/24%20Pages%20from%20NUR%20HASSANAH%20BINTI%20MOHD%20HASSAN.pdf
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id	my-usm-ep.61321
record_format	uketd_dc
spelling	my-usm-ep.613212024-10-17T03:31:57Z Optimizing The Production Of Short-Peptide Tagged Ss3A Recombinant Protein As A Potential Serological Biomarker For Strongyloidiasis 2023-02 Hassan, Nur Hassanah Mohd T1-995 Technology(General) Strongyloides stercoralis is a human-pathogenic nematode with a unique ability to autoinfect causing a parasitic disease called strongyloidiasis. Although listed as one of the neglected tropical diseases by World Health Organisation (WHO), the infection has a worldwide distribution with approximately 613.9 million cases mostly in tropical countries. Human infection occurs when the infective filariform S. stercoralis larvae in contaminated soil penetrate the intact skin through direct contact, travel to the mouth through bloodstream before it gets swallowed and resides in the gut. In the gut, female adult larvae produce eggs parthenogenetically, continuing their life cycle without having to leave the host’s body through a process called autoinfection. In general, the post-infection symptoms vary in two different ways. In immunocompetent individuals, hosts usually exhibit minimal to no symptoms (asymptomatic) and causes a life-long infection whereas in immunosuppressed individuals, unchecked infection is highly inclinative towards developing hyperinfection syndrome, an event where the larvae over-proliferate and disseminate to organs including the lung, liver, and brain. 2023-02 Thesis http://eprints.usm.my/61321/ http://eprints.usm.my/61321/1/24%20Pages%20from%20NUR%20HASSANAH%20BINTI%20MOHD%20HASSAN.pdf application/pdf en public masters Perpustakaan Hamzah Sendut Pusat Ipv6 Termaju Negara
institution	Universiti Sains Malaysia
collection	USM Institutional Repository
language	English
topic	T1-995 Technology(General)
spellingShingle	T1-995 Technology(General) Hassan, Nur Hassanah Mohd Optimizing The Production Of Short-Peptide Tagged Ss3A Recombinant Protein As A Potential Serological Biomarker For Strongyloidiasis
description	Strongyloides stercoralis is a human-pathogenic nematode with a unique ability to autoinfect causing a parasitic disease called strongyloidiasis. Although listed as one of the neglected tropical diseases by World Health Organisation (WHO), the infection has a worldwide distribution with approximately 613.9 million cases mostly in tropical countries. Human infection occurs when the infective filariform S. stercoralis larvae in contaminated soil penetrate the intact skin through direct contact, travel to the mouth through bloodstream before it gets swallowed and resides in the gut. In the gut, female adult larvae produce eggs parthenogenetically, continuing their life cycle without having to leave the host’s body through a process called autoinfection. In general, the post-infection symptoms vary in two different ways. In immunocompetent individuals, hosts usually exhibit minimal to no symptoms (asymptomatic) and causes a life-long infection whereas in immunosuppressed individuals, unchecked infection is highly inclinative towards developing hyperinfection syndrome, an event where the larvae over-proliferate and disseminate to organs including the lung, liver, and brain.
format	Thesis
qualification_level	Master's degree
author	Hassan, Nur Hassanah Mohd
author_facet	Hassan, Nur Hassanah Mohd
author_sort	Hassan, Nur Hassanah Mohd
title	Optimizing The Production Of Short-Peptide Tagged Ss3A Recombinant Protein As A Potential Serological Biomarker For Strongyloidiasis
title_short	Optimizing The Production Of Short-Peptide Tagged Ss3A Recombinant Protein As A Potential Serological Biomarker For Strongyloidiasis
title_full	Optimizing The Production Of Short-Peptide Tagged Ss3A Recombinant Protein As A Potential Serological Biomarker For Strongyloidiasis
title_fullStr	Optimizing The Production Of Short-Peptide Tagged Ss3A Recombinant Protein As A Potential Serological Biomarker For Strongyloidiasis
title_full_unstemmed	Optimizing The Production Of Short-Peptide Tagged Ss3A Recombinant Protein As A Potential Serological Biomarker For Strongyloidiasis
title_sort	optimizing the production of short-peptide tagged ss3a recombinant protein as a potential serological biomarker for strongyloidiasis
granting_institution	Perpustakaan Hamzah Sendut
granting_department	Pusat Ipv6 Termaju Negara
publishDate	2023
url	http://eprints.usm.my/61321/1/24%20Pages%20from%20NUR%20HASSANAH%20BINTI%20MOHD%20HASSAN.pdf
_version_	1818647394789621760

Optimizing The Production Of Short-Peptide Tagged Ss3A Recombinant Protein As A Potential Serological Biomarker For Strongyloidiasis

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