Study on nanodot OSLD in air cavity using 12 MeV electron beam radiotherapy

Electron beam radiotherapy is valued for its ability to precisely target cancerous tissues while minimizing damage to healthy ones, but it faces challenges when air cavity disrupts the intended dose distribution. Accurate dosimetry is crucial to ensure the prescribed dose reaches the target while sp...

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Main Author:	Othman, Farahamizah
Format:	Thesis
Language:	English
Published:	2024
Subjects:	R Medicine
Online Access:	http://eprints.usm.my/61345/1/Farahamizah%20Othman-E.pdf
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id	my-usm-ep.61345
record_format	uketd_dc
spelling	my-usm-ep.613452024-11-03T02:22:33Z Study on nanodot OSLD in air cavity using 12 MeV electron beam radiotherapy 2024-07 Othman, Farahamizah R Medicine Electron beam radiotherapy is valued for its ability to precisely target cancerous tissues while minimizing damage to healthy ones, but it faces challenges when air cavity disrupts the intended dose distribution. Accurate dosimetry is crucial to ensure the prescribed dose reaches the target while sparing healthy tissues. This research focuses on analyzing Percentage Depth Dose (PDD) curves using Optically Stimulated Luminescent Dosimeters (OSLD) and comparing them with Ionization Chamber measurements under varying air cavity thicknesses (4 cm, 6 cm, and 8 cm). The study utilized a linear accelerator at 12 MeV, employing solid water phantoms to simulate tissue and expanded polystyrene for air cavities. Measurements were taken at different depths to evaluate how air cavities affect dose distribution. The results revealed discrepancies between OSLD and Ionization Chamber measurements, with OSLD generally overestimating the dose, especially in the buildup region. In this study, both Optically Stimulated Luminescent Dosimeters (OSLD) and Ionization Chambers demonstrated closer agreement in dose measurements below the air cavity, with discrepancies of 31.7, 12.9, and 3.1 observed across all cavity thicknesses. However, both methods struggled to accurately estimate doses at the centre and surface of the air cavity. Universiti Sains Malaysia 2024-07 Thesis http://eprints.usm.my/61345/ http://eprints.usm.my/61345/1/Farahamizah%20Othman-E.pdf application/pdf en public phd doctoral Universiti Sains Malaysia Pusat Pengajian Sains Kesihatan
institution	Universiti Sains Malaysia
collection	USM Institutional Repository
language	English
topic	R Medicine
spellingShingle	R Medicine Othman, Farahamizah Study on nanodot OSLD in air cavity using 12 MeV electron beam radiotherapy
description	Electron beam radiotherapy is valued for its ability to precisely target cancerous tissues while minimizing damage to healthy ones, but it faces challenges when air cavity disrupts the intended dose distribution. Accurate dosimetry is crucial to ensure the prescribed dose reaches the target while sparing healthy tissues. This research focuses on analyzing Percentage Depth Dose (PDD) curves using Optically Stimulated Luminescent Dosimeters (OSLD) and comparing them with Ionization Chamber measurements under varying air cavity thicknesses (4 cm, 6 cm, and 8 cm). The study utilized a linear accelerator at 12 MeV, employing solid water phantoms to simulate tissue and expanded polystyrene for air cavities. Measurements were taken at different depths to evaluate how air cavities affect dose distribution. The results revealed discrepancies between OSLD and Ionization Chamber measurements, with OSLD generally overestimating the dose, especially in the buildup region. In this study, both Optically Stimulated Luminescent Dosimeters (OSLD) and Ionization Chambers demonstrated closer agreement in dose measurements below the air cavity, with discrepancies of 31.7, 12.9, and 3.1 observed across all cavity thicknesses. However, both methods struggled to accurately estimate doses at the centre and surface of the air cavity.
format	Thesis
qualification_name	Doctor of Philosophy (PhD.)
qualification_level	Doctorate
author	Othman, Farahamizah
author_facet	Othman, Farahamizah
author_sort	Othman, Farahamizah
title	Study on nanodot OSLD in air cavity using 12 MeV electron beam radiotherapy
title_short	Study on nanodot OSLD in air cavity using 12 MeV electron beam radiotherapy
title_full	Study on nanodot OSLD in air cavity using 12 MeV electron beam radiotherapy
title_fullStr	Study on nanodot OSLD in air cavity using 12 MeV electron beam radiotherapy
title_full_unstemmed	Study on nanodot OSLD in air cavity using 12 MeV electron beam radiotherapy
title_sort	study on nanodot osld in air cavity using 12 mev electron beam radiotherapy
granting_institution	Universiti Sains Malaysia
granting_department	Pusat Pengajian Sains Kesihatan
publishDate	2024
url	http://eprints.usm.my/61345/1/Farahamizah%20Othman-E.pdf
_version_	1818647399004897280

Study on nanodot OSLD in air cavity using 12 MeV electron beam radiotherapy

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