Modeling and control of quartz crystal operated in liquid for bio-sensing application
Nowadays the applications of sensors are a very promising research field since they find application in many different areas. Biosensors are an increasingly important technology in the detection of compounds ranging from pesticides to biological weapons. Typically, biosensors consist of a biol...
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| Main Author: | |
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| Format: | Thesis |
| Language: | English English English |
| Published: |
2014
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| Subjects: | |
| Online Access: | http://eprints.uthm.edu.my/1424/1/24p%20ABU%20ABDULLAH%20A.%20KADHIM%20FAHAD.pdf http://eprints.uthm.edu.my/1424/2/ABU%20ABDULLAH%20A.%20KADHIM%20FAHAD%20COPYRIGHT%20DECLARATION.pdf http://eprints.uthm.edu.my/1424/3/ABU%20ABDULLAH%20A.%20KADHIM%20FAHAD%20WATERMARK.pdf |
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| Summary: | Nowadays the applications of sensors are a very promising research field since they
find application in many different areas. Biosensors are an increasingly important
technology in the detection of compounds ranging from pesticides to biological
weapons. Typically, biosensors consist of a biological macromolecule that is
immobilized on the surface of a signal transducer. As the macromolecule binds
specifically to the ligand being detected, the signal transducer can measure a physical
change due to the binding event. One promising type of detector is the Quartz Crystal
Microbalance (QCM). The QCM is a piezoelectric mass-sensing device. A QCM
device works by sending an electrical signal through a gold-plated quartz crystal,
which causes a vibration at some resonant frequency. The QCM then measures the
frequency of oscillation in the crystal. When used as a biosensor, the QCM can
detect changes in frequency of the crystal due to changes in mass on the surface of
the crystal. In the present work, all related equations and data base related to
biosensors piezoelectric devices will be considered in the developed model. The
model will describe biosensors limitations and capacities together with measurement
resolutions and errors. The work will includes build of software program using
Microsoft visual studio C# 2010.net frame work 4.0 and all available theoretical and
empirical formulas and program data base will include the data for QCM sensors and
resonance frequencies, this program will include all cases needed to be studied for
the present work (bio sensing). Many sensors can be used for QCM, the present work
will be limited to TSM sensors, and the proposed software for Bio-sensing. The
frequency signal is detected by a frequency counter and processed electronically in a
separate computer. The QCM sensor used is 19.5 MHZ using buffer media in the
testing procedure. The result according to z-methods indicates that while the
resonance frequencies increase the small amount of despite material can be easily
detected. With the data extracted for (5 MHZ) sensors with effective area of 14 mm2
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the results show that as the change in resonance frequency increase as the despite
material increase. The film thickness of deposit material increase as the natural
frequencies of sensors decreased. |
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