FSI analysis of artery suffering atherosclerosis

From the statistics of international death rates, United States shows 169.4 per 100,000 of population death in year 2005 because of coronary heart disease (CHD). An atheroma is an accumulation and swelling an artery walls that made up of (mostly) macrophage cells, or debris, that contain lipids (...

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Main Author:	Chee, Kwok Chien
Format:	Thesis
Language:	English English English
Published:	2011
Subjects:	TA Engineering (General) Civil engineering (General)
Online Access:	http://eprints.uthm.edu.my/2601/1/24p%20CHEE%20KWOK%20CHIEN.pdf http://eprints.uthm.edu.my/2601/2/CHEE%20KWOK%20CHIEN%20COPYRIGHT%20DECLARATION.pdf http://eprints.uthm.edu.my/2601/3/CHEE%20KWOK%20CHIEN%20WATERMARK.pdf
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id	my-uthm-ep.2601
record_format	uketd_dc
spelling	my-uthm-ep.26012021-11-01T03:14:02Z FSI analysis of artery suffering atherosclerosis 2011-12 Chee, Kwok Chien TA Engineering (General). Civil engineering (General) TA329-348 Engineering mathematics. Engineering analysis From the statistics of international death rates, United States shows 169.4 per 100,000 of population death in year 2005 because of coronary heart disease (CHD). An atheroma is an accumulation and swelling an artery walls that made up of (mostly) macrophage cells, or debris, that contain lipids (cholesterol and fatty acids), calcium and a variable amount of fibrous connective tissue. It results the artery wall thickens and hardens. This is called as atherosclerosis or “hardening of the arteries“. Thus, will resulting in a heart attact and ensuing debility. In this project, a Fluid – Structure Interaction analysis is done on a blood flow in an artery which suffers atherosclerosis disease. The most often atherosclerotic plaque accumulate is at the abdominnal aorta. This analysis is done on a simplified model of abdominal aorta. The conditions to be analyze is regarding to the size and the stiffness of the atheroma. The software tools that using in this research is the ANSYS Workbench, with the coupling of ANSYS and CFX analysis. The output result of structural analysis of the abdominal aorta shows that the abdominal with the size of 15% atheroma shows the highest value of the Maximum Total Mesh Displacement and Von Mises Stress. While the result of fluid analysis of the blood flow in abdominal aorta shows that the increases of size and stiffness of atherma will increases the absolute gradient for the pressure and velocity of blood flow at the point 3 in analysis. However, the increases of absolute gradient of velocity and pressure of blood flow for the increases of atheroma stiffness is lower than the increases of absolute gradient of velocity and pressure of blood flow for the increases of atheroma size. Thus, the visualization of the interaction between blood flow and artery wall in the vicinity of atheroma will help medical researchers and doctor understand atherosclerosis better. 2011-12 Thesis http://eprints.uthm.edu.my/2601/ http://eprints.uthm.edu.my/2601/1/24p%20CHEE%20KWOK%20CHIEN.pdf text en public http://eprints.uthm.edu.my/2601/2/CHEE%20KWOK%20CHIEN%20COPYRIGHT%20DECLARATION.pdf text en staffonly http://eprints.uthm.edu.my/2601/3/CHEE%20KWOK%20CHIEN%20WATERMARK.pdf text en validuser mphil masters Universiti Tun Hussein Malaysia Fakulti Kejuruteraan Mekanikal dan Pembuatan
institution	Universiti Tun Hussein Onn Malaysia
collection	UTHM Institutional Repository
language	English English English
topic	TA Engineering (General) Civil engineering (General) TA Engineering (General) Civil engineering (General)
spellingShingle	TA Engineering (General) Civil engineering (General) TA Engineering (General) Civil engineering (General) Chee, Kwok Chien FSI analysis of artery suffering atherosclerosis
description	From the statistics of international death rates, United States shows 169.4 per 100,000 of population death in year 2005 because of coronary heart disease (CHD). An atheroma is an accumulation and swelling an artery walls that made up of (mostly) macrophage cells, or debris, that contain lipids (cholesterol and fatty acids), calcium and a variable amount of fibrous connective tissue. It results the artery wall thickens and hardens. This is called as atherosclerosis or “hardening of the arteries“. Thus, will resulting in a heart attact and ensuing debility. In this project, a Fluid – Structure Interaction analysis is done on a blood flow in an artery which suffers atherosclerosis disease. The most often atherosclerotic plaque accumulate is at the abdominnal aorta. This analysis is done on a simplified model of abdominal aorta. The conditions to be analyze is regarding to the size and the stiffness of the atheroma. The software tools that using in this research is the ANSYS Workbench, with the coupling of ANSYS and CFX analysis. The output result of structural analysis of the abdominal aorta shows that the abdominal with the size of 15% atheroma shows the highest value of the Maximum Total Mesh Displacement and Von Mises Stress. While the result of fluid analysis of the blood flow in abdominal aorta shows that the increases of size and stiffness of atherma will increases the absolute gradient for the pressure and velocity of blood flow at the point 3 in analysis. However, the increases of absolute gradient of velocity and pressure of blood flow for the increases of atheroma stiffness is lower than the increases of absolute gradient of velocity and pressure of blood flow for the increases of atheroma size. Thus, the visualization of the interaction between blood flow and artery wall in the vicinity of atheroma will help medical researchers and doctor understand atherosclerosis better.
format	Thesis
qualification_name	Master of Philosophy (M.Phil.)
qualification_level	Master's degree
author	Chee, Kwok Chien
author_facet	Chee, Kwok Chien
author_sort	Chee, Kwok Chien
title	FSI analysis of artery suffering atherosclerosis
title_short	FSI analysis of artery suffering atherosclerosis
title_full	FSI analysis of artery suffering atherosclerosis
title_fullStr	FSI analysis of artery suffering atherosclerosis
title_full_unstemmed	FSI analysis of artery suffering atherosclerosis
title_sort	fsi analysis of artery suffering atherosclerosis
granting_institution	Universiti Tun Hussein Malaysia
granting_department	Fakulti Kejuruteraan Mekanikal dan Pembuatan
publishDate	2011
url	http://eprints.uthm.edu.my/2601/1/24p%20CHEE%20KWOK%20CHIEN.pdf http://eprints.uthm.edu.my/2601/2/CHEE%20KWOK%20CHIEN%20COPYRIGHT%20DECLARATION.pdf http://eprints.uthm.edu.my/2601/3/CHEE%20KWOK%20CHIEN%20WATERMARK.pdf
_version_	1747830968314494976

FSI analysis of artery suffering atherosclerosis

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