Design and development of groove micromixer for laminar blood-reagent mixing

Mixing of two fluids is an essential process for most of microfluidic device for Biomedical Micro-Electro-Mechanical System (Bio-MEMS) application. Mixing also important in Lab-On-Chip (LOC) system because the chemical reaction carried out in this system requires on-chip mixing. Mixing performanc...

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Main Author:	Abdul Rahim, Suraya
Format:	Thesis
Language:	English English English
Published:	2013
Subjects:	TA349-359 Mechanics of engineering Applied mechanics
Online Access:	http://eprints.uthm.edu.my/6816/1/24p%20SITI%20NUR%20HIDAYAH%20AB.%20MALEK.pdf http://eprints.uthm.edu.my/6816/2/SITI%20NUR%20HIDAYAH%20AB.%20MALEK%20COPYRIGHT%20DECLARATION.pdf http://eprints.uthm.edu.my/6816/3/SITI%20NUR%20HIDAYAH%20AB.%20MALEK%20WATERMARK.pdf
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id	my-uthm-ep.6816
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spelling	my-uthm-ep.68162022-03-22T01:20:46Z Design and development of groove micromixer for laminar blood-reagent mixing 2013-07 Abdul Rahim, Suraya TA349-359 Mechanics of engineering. Applied mechanics Mixing of two fluids is an essential process for most of microfluidic device for Biomedical Micro-Electro-Mechanical System (Bio-MEMS) application. Mixing also important in Lab-On-Chip (LOC) system because the chemical reaction carried out in this system requires on-chip mixing. Mixing performance in this system relies mainly on effective and rapid mixing of sample and reagent. Therefore, development of groove micromixer for application of blood and reagent mixing carried out in this project. In this study, two fluids involve in the mixing, which is the blood and reagent (two type of reagent with lower and higher viscosity compared to blood). Two pattern of the groove namely oblique groove and herringbone groove were designed and simulated using CoventorWare2010 software at low Reynolds number. The design of groove micromixer obtained by analyzing the geometries effect of groove pattern on mixing performance of blood and reagent with the visualization of simulation and evaluation of mixing performance for difference geometry parameter of groove micromixer. In this study, it has been demonstrated that the Y-Shape mixer with the groove structure located at the floor of the mixing channel increased the mixing performance. Thus, the simulation result in this study shows that mixing performance can be enhanced when depth and width of groove is 40% of the channel width with the angle of an oblique groove is 45º. Whereas for the herringbone mixer, enhancement of mixing performance occured when the depth and width of herringbone groove is 25% of the channel width with the approximation of asymmetric index is quarter of the width of mixing channel. 2013-07 Thesis http://eprints.uthm.edu.my/6816/ http://eprints.uthm.edu.my/6816/1/24p%20SITI%20NUR%20HIDAYAH%20AB.%20MALEK.pdf text en public http://eprints.uthm.edu.my/6816/2/SITI%20NUR%20HIDAYAH%20AB.%20MALEK%20COPYRIGHT%20DECLARATION.pdf text en staffonly http://eprints.uthm.edu.my/6816/3/SITI%20NUR%20HIDAYAH%20AB.%20MALEK%20WATERMARK.pdf text en validuser mphil masters Universiti Tun Hussein Malaysia Fakulti Kejuruteraan Elektrik dan Elektronik
institution	Universiti Tun Hussein Onn Malaysia
collection	UTHM Institutional Repository
language	English English English
topic	TA349-359 Mechanics of engineering Applied mechanics
spellingShingle	TA349-359 Mechanics of engineering Applied mechanics Abdul Rahim, Suraya Design and development of groove micromixer for laminar blood-reagent mixing
description	Mixing of two fluids is an essential process for most of microfluidic device for Biomedical Micro-Electro-Mechanical System (Bio-MEMS) application. Mixing also important in Lab-On-Chip (LOC) system because the chemical reaction carried out in this system requires on-chip mixing. Mixing performance in this system relies mainly on effective and rapid mixing of sample and reagent. Therefore, development of groove micromixer for application of blood and reagent mixing carried out in this project. In this study, two fluids involve in the mixing, which is the blood and reagent (two type of reagent with lower and higher viscosity compared to blood). Two pattern of the groove namely oblique groove and herringbone groove were designed and simulated using CoventorWare2010 software at low Reynolds number. The design of groove micromixer obtained by analyzing the geometries effect of groove pattern on mixing performance of blood and reagent with the visualization of simulation and evaluation of mixing performance for difference geometry parameter of groove micromixer. In this study, it has been demonstrated that the Y-Shape mixer with the groove structure located at the floor of the mixing channel increased the mixing performance. Thus, the simulation result in this study shows that mixing performance can be enhanced when depth and width of groove is 40% of the channel width with the angle of an oblique groove is 45º. Whereas for the herringbone mixer, enhancement of mixing performance occured when the depth and width of herringbone groove is 25% of the channel width with the approximation of asymmetric index is quarter of the width of mixing channel.
format	Thesis
qualification_name	Master of Philosophy (M.Phil.)
qualification_level	Master's degree
author	Abdul Rahim, Suraya
author_facet	Abdul Rahim, Suraya
author_sort	Abdul Rahim, Suraya
title	Design and development of groove micromixer for laminar blood-reagent mixing
title_short	Design and development of groove micromixer for laminar blood-reagent mixing
title_full	Design and development of groove micromixer for laminar blood-reagent mixing
title_fullStr	Design and development of groove micromixer for laminar blood-reagent mixing
title_full_unstemmed	Design and development of groove micromixer for laminar blood-reagent mixing
title_sort	design and development of groove micromixer for laminar blood-reagent mixing
granting_institution	Universiti Tun Hussein Malaysia
granting_department	Fakulti Kejuruteraan Elektrik dan Elektronik
publishDate	2013
url	http://eprints.uthm.edu.my/6816/1/24p%20SITI%20NUR%20HIDAYAH%20AB.%20MALEK.pdf http://eprints.uthm.edu.my/6816/2/SITI%20NUR%20HIDAYAH%20AB.%20MALEK%20COPYRIGHT%20DECLARATION.pdf http://eprints.uthm.edu.my/6816/3/SITI%20NUR%20HIDAYAH%20AB.%20MALEK%20WATERMARK.pdf
_version_	1747831091639615488

Design and development of groove micromixer for laminar blood-reagent mixing

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