Implementation of luo-rudi phase 1 cardiac cell excitation model in FPGA

Dynamic simulation of complex cardiac excitation and conduction requires high computational time. Thus, the hardware techniques that can run in the real-time simulation was introduced. However, previously developed hardware simulation requires high power consumption and has a large physical size. Du...

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Main Author:	Othman, Norliza
Format:	Thesis
Language:	English English English
Published:	2017
Subjects:	RC Internal medicine RC581-951 Specialties of internal medicine
Online Access:	http://eprints.uthm.edu.my/7827/1/24p%20NORLIZA%20OTHMAN.pdf http://eprints.uthm.edu.my/7827/2/NORLIZA%20OTHMAN%20COPYRIGHT%20DECLARATION.pdf http://eprints.uthm.edu.my/7827/3/NORLIZA%20OTHMAN%20WATERMARK.pdf
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id	my-uthm-ep.7827
record_format	uketd_dc
spelling	my-uthm-ep.78272022-10-12T02:23:23Z Implementation of luo-rudi phase 1 cardiac cell excitation model in FPGA 2017-04 Othman, Norliza RC Internal medicine RC581-951 Specialties of internal medicine Dynamic simulation of complex cardiac excitation and conduction requires high computational time. Thus, the hardware techniques that can run in the real-time simulation was introduced. However, previously developed hardware simulation requires high power consumption and has a large physical size. Due to the drawbacks, this research presents the adaptation of Luo-Rudy Phase I (LR-I) cardiac excitation model in a rapid prototyping method of field programmable gate array (FPGA) for real-time simulation, lower power consumption and minimizing the size. For the rapid prototyping, a nonlinear Ordinary Differential Equation (ODE)based algorithm of the LR-I model is implemented by using Hardware Description Language (I-IDL) Coder that is capable to convert MATLAB Simulink blocks designed into a synthesisable VHSIC Hardware Description Language (VHDL) code and verified using the FPGA-In-the Loop (FIL) Co-simulator. The Xilinx FPGA Yirtex-6 XC6VLX240T ML605 evaluation board is chosen as a platform for the FPGA high performance system which is supported by the 1-lDL Coder. A fixedpoint optimisation has been successfully obtained with Percentage Error (PE) and Mean Square Error (MSE) which are -1.08% and 2.28%, respectively. This result has given better performance for the hardware implementation in terms of 27.5% decrement in power consumption and 5.35% decrement in utilization area with maximum frequency 9.819 MHz. By implementing the constructed algorithm into the high performance FPGA system, a new real-time simulation-based analysis technique of cardiac electrical excitation has been successfully developed. 2017-04 Thesis http://eprints.uthm.edu.my/7827/ http://eprints.uthm.edu.my/7827/1/24p%20NORLIZA%20OTHMAN.pdf text en public http://eprints.uthm.edu.my/7827/2/NORLIZA%20OTHMAN%20COPYRIGHT%20DECLARATION.pdf text en staffonly http://eprints.uthm.edu.my/7827/3/NORLIZA%20OTHMAN%20WATERMARK.pdf text en validuser mphil masters Universiti Tun Hussein Onn Malaysia Fakulti Kejuruteraan Elektrik dan Elektronik
institution	Universiti Tun Hussein Onn Malaysia
collection	UTHM Institutional Repository
language	English English English
topic	RC Internal medicine RC581-951 Specialties of internal medicine
spellingShingle	RC Internal medicine RC581-951 Specialties of internal medicine Othman, Norliza Implementation of luo-rudi phase 1 cardiac cell excitation model in FPGA
description	Dynamic simulation of complex cardiac excitation and conduction requires high computational time. Thus, the hardware techniques that can run in the real-time simulation was introduced. However, previously developed hardware simulation requires high power consumption and has a large physical size. Due to the drawbacks, this research presents the adaptation of Luo-Rudy Phase I (LR-I) cardiac excitation model in a rapid prototyping method of field programmable gate array (FPGA) for real-time simulation, lower power consumption and minimizing the size. For the rapid prototyping, a nonlinear Ordinary Differential Equation (ODE)based algorithm of the LR-I model is implemented by using Hardware Description Language (I-IDL) Coder that is capable to convert MATLAB Simulink blocks designed into a synthesisable VHSIC Hardware Description Language (VHDL) code and verified using the FPGA-In-the Loop (FIL) Co-simulator. The Xilinx FPGA Yirtex-6 XC6VLX240T ML605 evaluation board is chosen as a platform for the FPGA high performance system which is supported by the 1-lDL Coder. A fixedpoint optimisation has been successfully obtained with Percentage Error (PE) and Mean Square Error (MSE) which are -1.08% and 2.28%, respectively. This result has given better performance for the hardware implementation in terms of 27.5% decrement in power consumption and 5.35% decrement in utilization area with maximum frequency 9.819 MHz. By implementing the constructed algorithm into the high performance FPGA system, a new real-time simulation-based analysis technique of cardiac electrical excitation has been successfully developed.
format	Thesis
qualification_name	Master of Philosophy (M.Phil.)
qualification_level	Master's degree
author	Othman, Norliza
author_facet	Othman, Norliza
author_sort	Othman, Norliza
title	Implementation of luo-rudi phase 1 cardiac cell excitation model in FPGA
title_short	Implementation of luo-rudi phase 1 cardiac cell excitation model in FPGA
title_full	Implementation of luo-rudi phase 1 cardiac cell excitation model in FPGA
title_fullStr	Implementation of luo-rudi phase 1 cardiac cell excitation model in FPGA
title_full_unstemmed	Implementation of luo-rudi phase 1 cardiac cell excitation model in FPGA
title_sort	implementation of luo-rudi phase 1 cardiac cell excitation model in fpga
granting_institution	Universiti Tun Hussein Onn Malaysia
granting_department	Fakulti Kejuruteraan Elektrik dan Elektronik
publishDate	2017
url	http://eprints.uthm.edu.my/7827/1/24p%20NORLIZA%20OTHMAN.pdf http://eprints.uthm.edu.my/7827/2/NORLIZA%20OTHMAN%20COPYRIGHT%20DECLARATION.pdf http://eprints.uthm.edu.my/7827/3/NORLIZA%20OTHMAN%20WATERMARK.pdf
_version_	1747831198572347392

Implementation of luo-rudi phase 1 cardiac cell excitation model in FPGA

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