Analysis on the flow and pressure distribution for actual stenosis in trachea

Analysis on the flow and pressure distribution for actual stenosis in trachea

Knowledge of flow inside the human airway is very important for medical practitioner to make accurate diagnosis. With the presence stenosis inside the airway, the flow will be changed significantly and will directly affect the input to the main bronchi. In this study, patient-specific image is used...

Full description

Saved in:
Bibliographic Details
Main Author: Mohd. Salleh, Zuliazura
Format: Thesis
Language:English
Published: 2010
Subjects:
QA Mathematics
Online Access:http://eprints.utm.my/id/eprint/12825/1/ZuliazuraMohdSallehMFKM2010.pdf
Tags: Add Tag
No Tags, Be the first to tag this record!
id my-utm-ep.12825
record_format uketd_dc
institution Universiti Teknologi Malaysia
collection UTM Institutional Repository
language English
topic QA Mathematics
spellingShingle QA Mathematics
Mohd. Salleh, Zuliazura
Analysis on the flow and pressure distribution for actual stenosis in trachea
description Knowledge of flow inside the human airway is very important for medical practitioner to make accurate diagnosis. With the presence stenosis inside the airway, the flow will be changed significantly and will directly affect the input to the main bronchi. In this study, patient-specific image is used and remodelled using computational fluid dynamic software to simulate the flow within the trachea. The image contains one stenosis which was then reconstructed to other locations. This procedure will enable the study of flow behaviour in the trachea with different stenosis locations. Emphasis of analysis is focused on the flow and pressure distribution along the main airway. For each model, computations were carried out in three different flow rates which are 15 l/min, 60 l/min and 100 l/min corresponding to regular human activity which are resting, normal and heavy excersice breathing, respectively. The results show as stenosis located at the upper third of the trachea, the pressure drop along the trachea are insignificant in every breathing condition but differ to the velocity where the maximum velocity is increase as the flow rate increase. For stenosis located at the lower third or the trachea, both pressure drop and velocity did effect clearly as the flow rate increase. The effect of different location of the stenosis on the velocity distribution along the centerline shows similar increment in every flow rate and the risk in breathing difficulties if the patient having a stenosis at the third location is three times higher compare to the first location if the patient in resting condition. It increases to five times higher when doing the regular activity and eight times higher if the patient doing heavy exercise. The comparison is based on the same size of the stenosis.
format Thesis
qualification_level Master's degree
author Mohd. Salleh, Zuliazura
author_facet Mohd. Salleh, Zuliazura
author_sort Mohd. Salleh, Zuliazura
title Analysis on the flow and pressure distribution for actual stenosis in trachea
title_short Analysis on the flow and pressure distribution for actual stenosis in trachea
title_full Analysis on the flow and pressure distribution for actual stenosis in trachea
title_fullStr Analysis on the flow and pressure distribution for actual stenosis in trachea
title_full_unstemmed Analysis on the flow and pressure distribution for actual stenosis in trachea
title_sort analysis on the flow and pressure distribution for actual stenosis in trachea
granting_institution Universiti Teknologi Malaysia, Faculty of Mechanical Engineering
granting_department Faculty of Mechanical Engineering
publishDate 2010
url http://eprints.utm.my/id/eprint/12825/1/ZuliazuraMohdSallehMFKM2010.pdf
_version_ 1747814959040954368
spelling my-utm-ep.128252017-09-13T03:40:30Z Analysis on the flow and pressure distribution for actual stenosis in trachea 2010 Mohd. Salleh, Zuliazura QA Mathematics Knowledge of flow inside the human airway is very important for medical practitioner to make accurate diagnosis. With the presence stenosis inside the airway, the flow will be changed significantly and will directly affect the input to the main bronchi. In this study, patient-specific image is used and remodelled using computational fluid dynamic software to simulate the flow within the trachea. The image contains one stenosis which was then reconstructed to other locations. This procedure will enable the study of flow behaviour in the trachea with different stenosis locations. Emphasis of analysis is focused on the flow and pressure distribution along the main airway. For each model, computations were carried out in three different flow rates which are 15 l/min, 60 l/min and 100 l/min corresponding to regular human activity which are resting, normal and heavy excersice breathing, respectively. The results show as stenosis located at the upper third of the trachea, the pressure drop along the trachea are insignificant in every breathing condition but differ to the velocity where the maximum velocity is increase as the flow rate increase. For stenosis located at the lower third or the trachea, both pressure drop and velocity did effect clearly as the flow rate increase. The effect of different location of the stenosis on the velocity distribution along the centerline shows similar increment in every flow rate and the risk in breathing difficulties if the patient having a stenosis at the third location is three times higher compare to the first location if the patient in resting condition. It increases to five times higher when doing the regular activity and eight times higher if the patient doing heavy exercise. The comparison is based on the same size of the stenosis. 2010 Thesis http://eprints.utm.my/id/eprint/12825/ http://eprints.utm.my/id/eprint/12825/1/ZuliazuraMohdSallehMFKM2010.pdf application/pdf en public masters Universiti Teknologi Malaysia, Faculty of Mechanical Engineering Faculty of Mechanical Engineering 1. Brouns, M., Jayaraju, S. T., Lacor, C., Mey, J. D., Noppen, M., Vincken, W., et al. (2007). Tracheal stenosis: a flow dynamics study. J Appl Physiol , 102: 1178-1184. 2. Calay, R. K., Kurujareon, ,. J., & Holdo, A. E. (2002). Numerical Simulation of Respiratory Flow Patterns within Human Lung. Elsevier , 130:201-221. 3. Cebral, J., & Summers, R. (2004). Tracheal and central bronchial aerodynamics using virtual bronchoscopy and computational fluid dynamics. Medical Imaging , 8:1021 - 1033. 4. CHOI, L.-T., & TU, J. (2007). FLOW AND PARTICLE DEPOSITION PATTERNS IN A REALISTIC HUMAN DOUBLE BIFURCATION AIRWAY MODEL. Fifth International Conference on CFD in the Process Industries , 19:117–31. 5. Freitag, L., Unger, M., Ernst, A., Kovits, K., & Marquette, C. (2007). A proposed classification system of central airway stenosis. European Respiratory Journal . 6. Gemci, T., Ponyavin, V., Chen, Y., Chen, H., & Collins, R. (2007). CFD Simulation of Airflow in a 17-Generation Digital Reference Model of the Human Bronchial Tree. Biomechanics . 7. Guan, X., & Martonen, T. B. (2000). FLOW TRANSITION IN BENDS AND APPLICATIONS TO AIRWAYS. J. Aerosol Sci , 31: 833-847, . 8. Hammer, J. r. (2004). Acquired upper airway obstruction. PAEDIATRIC RESPIRATORY , 5:25–33. 9. Heged´us, C. J., Balásházy, I., & Farkas, Á. ( 2004). Detailed mathematical description of the geometry of airway bifurcations. Respiratory Physiology & Neurobiology , 141:99– 114. 10. Jayaraju, S. T., Brouns, M., Lacor, C., Mey, J. D., & Verbanck, S. (2006). EFFECTS OF TRACHEAL STENOSIS ON FLOW. European Conference on Computational Fluid Dynamics 11. Lam, W. W.-m., Tam, P. K., Chan, F.-L., Chan, K.-l., & Cheng, W. (2000). Esophageal Atresia and Tracheal Stenosis:Use of Three-Dimensional CT and Virtual Bronchoscopy in Neonates, Infants, and Children. American Roentgen , 174:1009–1012. 12. Lin, C.-L., Tawhai, M. H., McLennanc, G., & Hoffmanc, E. A. (2007). Characteristics of the turbulent laryngeal jet and its effect on. Respiratory Physiology & Neurobiology , 157:295–309. 13. Luo, X. Y., Hinton, J. S., Liew, T. T., & Tan, K. K. (2004). LES Modeling of Flow in a Simple Airway Model. Medical Engineering and Physics . 14. Russo, J., Robinson, R., & Oldhamb, M. J. (2008). Effects of cartilage rings on airflow and particle deposition in the trachea and main bronchi. Medical Engineering & Physics , 30: 581–589. 15. Spittle, N., & McCluskey, A. (2000). Tracheal stenosis after intubation. PubMed Central , 321(7267): 1000–1002. 16. Yang, J. H., Jun, T. G., Sung, K., Choi, J. H., Lee, Y. T., & Park, P. W. (2007). Repair of Long-segment Congenital Tracheal Stenosis. J Korean Med Sci , 22: 491-496.

Similar Items