Development of method for simultaneous determination of plasticizers in plastic food packaging by gas chromatography

An analytical method has been developed for the simultaneous determination of plasticizers belonging to the classes of phthalates, adipates, sebacates, azelates, phosphates, glycolate, citrates, and trimellitates which are often present in plastic food packaging. Sample extraction consists of sol...

Full description

Saved in:

Bibliographic Details
Main Author:	Nasir, Zalilah
Format:	Thesis
Language:	English
Published:	2008
Subjects:	QD Chemistry
Online Access:	http://eprints.utm.my/id/eprint/18000/1/ZalilahNasirMFS2008.pdf
Tags:	Add Tag No Tags, Be the first to tag this record!

id	my-utm-ep.18000
record_format	uketd_dc
spelling	my-utm-ep.180002018-07-25T08:01:20Z Development of method for simultaneous determination of plasticizers in plastic food packaging by gas chromatography 2008 Nasir, Zalilah QD Chemistry An analytical method has been developed for the simultaneous determination of plasticizers belonging to the classes of phthalates, adipates, sebacates, azelates, phosphates, glycolate, citrates, and trimellitates which are often present in plastic food packaging. Sample extraction consists of solvent dissolution, precipitation, centrifugation, and concentration steps before analysis by gas chromatography with flame ionization detector (GC-FID). The developed analytical procedure makes possible the simultaneous determination of 20 compounds in common plastic materials for food packaging industry, namely dimethyl phthalate, diethyl phthalate, diisopropyl phthalate, di-n-propyl phthalate, diisobutyl phthalate, di-n-butyl phthalate, dipentyl phthalate, din- butyl sebacate, acetyl-tri-n-butyl citrate, butylphthalyl butyl glycolate, butylbenzyl phthalate, dihexyl phthalate, di-2-ethylhexyl adipate, tri-2-ethylhexyl phosphate, dichlorohexyl phthalate, di-2-ethylhexyl phthalate, tri-n-butyl trimellitate, di-2- ethylhexyl azelate, di-n-octyl phthalate and tri-2-ethylhexyl trimellitate within 35 minutes of gas chromatographic separation. Performance characteristics of the method such as linearity range, detection and quantification limit, specificity, trueness and precision were studied and were found to be within the acceptable limit for each plasticizer type. With the limit of detection between 0.61 to 2.88 mg/kg, the method was successfully applied to the determination of plasticizers in plastic food packaging made of polyvinyl chloride, polyvinylidene chloride, polystyrene and polycarbonate. The method was found to be reliable, not labor intensive, suitable for general use and offer considerable time savings over the individual methods available to date. Thus, the proposed method could be used by many agencies including industries’ own quality control laboratories and enforcement authorities in charge with ensuring plastic food packaging meet applicable regulations. 2008 Thesis http://eprints.utm.my/id/eprint/18000/ http://eprints.utm.my/id/eprint/18000/1/ZalilahNasirMFS2008.pdf application/pdf en public http://dms.library.utm.my:8080/vital/access/manager/Repository/vital:1122?queryType=vitalDismax&query=Development+of+method+for+simultaneous+determination+of+plasticizers+in+plastic+food+packaging+by+gas+chromatography&public=true masters Universiti Teknologi Malaysia, Faculty of Science Faculty of Science
institution	Universiti Teknologi Malaysia
collection	UTM Institutional Repository
language	English
topic	QD Chemistry
spellingShingle	QD Chemistry Nasir, Zalilah Development of method for simultaneous determination of plasticizers in plastic food packaging by gas chromatography
description	An analytical method has been developed for the simultaneous determination of plasticizers belonging to the classes of phthalates, adipates, sebacates, azelates, phosphates, glycolate, citrates, and trimellitates which are often present in plastic food packaging. Sample extraction consists of solvent dissolution, precipitation, centrifugation, and concentration steps before analysis by gas chromatography with flame ionization detector (GC-FID). The developed analytical procedure makes possible the simultaneous determination of 20 compounds in common plastic materials for food packaging industry, namely dimethyl phthalate, diethyl phthalate, diisopropyl phthalate, di-n-propyl phthalate, diisobutyl phthalate, di-n-butyl phthalate, dipentyl phthalate, din- butyl sebacate, acetyl-tri-n-butyl citrate, butylphthalyl butyl glycolate, butylbenzyl phthalate, dihexyl phthalate, di-2-ethylhexyl adipate, tri-2-ethylhexyl phosphate, dichlorohexyl phthalate, di-2-ethylhexyl phthalate, tri-n-butyl trimellitate, di-2- ethylhexyl azelate, di-n-octyl phthalate and tri-2-ethylhexyl trimellitate within 35 minutes of gas chromatographic separation. Performance characteristics of the method such as linearity range, detection and quantification limit, specificity, trueness and precision were studied and were found to be within the acceptable limit for each plasticizer type. With the limit of detection between 0.61 to 2.88 mg/kg, the method was successfully applied to the determination of plasticizers in plastic food packaging made of polyvinyl chloride, polyvinylidene chloride, polystyrene and polycarbonate. The method was found to be reliable, not labor intensive, suitable for general use and offer considerable time savings over the individual methods available to date. Thus, the proposed method could be used by many agencies including industries’ own quality control laboratories and enforcement authorities in charge with ensuring plastic food packaging meet applicable regulations.
format	Thesis
qualification_level	Master's degree
author	Nasir, Zalilah
author_facet	Nasir, Zalilah
author_sort	Nasir, Zalilah
title	Development of method for simultaneous determination of plasticizers in plastic food packaging by gas chromatography
title_short	Development of method for simultaneous determination of plasticizers in plastic food packaging by gas chromatography
title_full	Development of method for simultaneous determination of plasticizers in plastic food packaging by gas chromatography
title_fullStr	Development of method for simultaneous determination of plasticizers in plastic food packaging by gas chromatography
title_full_unstemmed	Development of method for simultaneous determination of plasticizers in plastic food packaging by gas chromatography
title_sort	development of method for simultaneous determination of plasticizers in plastic food packaging by gas chromatography
granting_institution	Universiti Teknologi Malaysia, Faculty of Science
granting_department	Faculty of Science
publishDate	2008
url	http://eprints.utm.my/id/eprint/18000/1/ZalilahNasirMFS2008.pdf
_version_	1747815168571604992

Development of method for simultaneous determination of plasticizers in plastic food packaging by gas chromatography

Similar Items