Parameter estimation of mean survival time using parametric and nonparametric approaches

Exploring health related quality of life is usually the focus of survival studies. Using the data of breast cancer, an investigation about the mean survival time of cancer patients was explored, using the nonparametric and parametric modeling approaches. The Kaplan-Meier method and three of the dist...

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Main Author: Ismail, Hasnah
Format: Thesis
Language:English
Published: 2011
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Online Access:http://eprints.utm.my/id/eprint/47958/25/HasnahIsmailMFS2011.pdf
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spelling my-utm-ep.479582018-05-30T03:39:33Z Parameter estimation of mean survival time using parametric and nonparametric approaches 2011-08 Ismail, Hasnah R Medicine (General) Exploring health related quality of life is usually the focus of survival studies. Using the data of breast cancer, an investigation about the mean survival time of cancer patients was explored, using the nonparametric and parametric modeling approaches. The Kaplan-Meier method and three of the distribution were considered in this study which is Weibull distribution, exponential distribution and lognormal distribution. Other than that, the Anderson Darling test is used to test if a sample data came from a population with a specific distribution. Based on the result, the data came from a Weibull distribution because the distribution has the minimum Anderson-Darling (adjusted) value. The simulation study has been done to see the efficiency of parametric and nonparametric estimator by observing the Relative Efficiency (RE) values. The results show that parametric estimator provide better estimates than the Kaplan-Meier estimator if the correct distribution is assumed. 2011-08 Thesis http://eprints.utm.my/id/eprint/47958/ http://eprints.utm.my/id/eprint/47958/25/HasnahIsmailMFS2011.pdf application/pdf en public masters Universiti Teknologi Malaysia, Faculty of Science Faculty of Science
institution Universiti Teknologi Malaysia
collection UTM Institutional Repository
language English
topic R Medicine (General)
spellingShingle R Medicine (General)
Ismail, Hasnah
Parameter estimation of mean survival time using parametric and nonparametric approaches
description Exploring health related quality of life is usually the focus of survival studies. Using the data of breast cancer, an investigation about the mean survival time of cancer patients was explored, using the nonparametric and parametric modeling approaches. The Kaplan-Meier method and three of the distribution were considered in this study which is Weibull distribution, exponential distribution and lognormal distribution. Other than that, the Anderson Darling test is used to test if a sample data came from a population with a specific distribution. Based on the result, the data came from a Weibull distribution because the distribution has the minimum Anderson-Darling (adjusted) value. The simulation study has been done to see the efficiency of parametric and nonparametric estimator by observing the Relative Efficiency (RE) values. The results show that parametric estimator provide better estimates than the Kaplan-Meier estimator if the correct distribution is assumed.
format Thesis
qualification_level Master's degree
author Ismail, Hasnah
author_facet Ismail, Hasnah
author_sort Ismail, Hasnah
title Parameter estimation of mean survival time using parametric and nonparametric approaches
title_short Parameter estimation of mean survival time using parametric and nonparametric approaches
title_full Parameter estimation of mean survival time using parametric and nonparametric approaches
title_fullStr Parameter estimation of mean survival time using parametric and nonparametric approaches
title_full_unstemmed Parameter estimation of mean survival time using parametric and nonparametric approaches
title_sort parameter estimation of mean survival time using parametric and nonparametric approaches
granting_institution Universiti Teknologi Malaysia, Faculty of Science
granting_department Faculty of Science
publishDate 2011
url http://eprints.utm.my/id/eprint/47958/25/HasnahIsmailMFS2011.pdf
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