Investigation on packaging material of counterfeit Panadol variants and Creobic cream by non-destructive tests

The World Health Organization (WHO) has defined counterfeit drugs as those which are “deliberately mislabelled with respect to identity and/or source”. Packaging materials are ubiquitous and manufacturers are able to obtain them from multiples of supplier. That is the reason for the unfeasible confi...

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Main Author:	Shamsuddin, Tuhfah Zahidah
Format:	Thesis
Language:	English
Published:	2014
Subjects:	HF Commerce
Online Access:	http://eprints.utm.my/id/eprint/48496/1/TuhfahZahidahShamsuddinMFS2014.pdf
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id	my-utm-ep.48496
record_format	uketd_dc
spelling	my-utm-ep.484962017-07-05T02:28:21Z Investigation on packaging material of counterfeit Panadol variants and Creobic cream by non-destructive tests 2014 Shamsuddin, Tuhfah Zahidah HF Commerce The World Health Organization (WHO) has defined counterfeit drugs as those which are “deliberately mislabelled with respect to identity and/or source”. Packaging materials are ubiquitous and manufacturers are able to obtain them from multiples of supplier. That is the reason for the unfeasible confiscation. There are a few methods used to detect counterfeit products through its packaging: visual inspection (visible light) and other optical methods such as infrared and ultraviolet analysis as well as pattern recognition. The objective of this study is to differentiate the features on the packaging material found from the original and the counterfeit of the same fast-moving pharmaceutical products. There are four different product packaging investigated obtained through over-the-counter purchase, from the complainant or seized by the authority. Firstly, examination is carried out on the direct paperboard packaging by comparison; physical examination on the basic properties (viz. dimension, thickness and prints), microscopic, optical character recognition (OCR) and near infrared analysis. Then, further investigation on the information printed and hologram serial number was done. Determination of the originality of the products upon procurement was done through authenticating the hologram. Microscopic examination on the printed paperboard exhibited consistent printing effect for all of the counterfeit and the genuine ones. Results on OCR for certain parts of the prints show constant difference between the original and counterfeit. However, the IR results indicated that such differences may prove inconsistent and hence unreliable to be used for comparison. In conclusion, the counterfeit pharmaceutical packaging may be distinguished from the genuine ones through physical examination of its basic properties, microscopic observation and OCR. 2014 Thesis http://eprints.utm.my/id/eprint/48496/ http://eprints.utm.my/id/eprint/48496/1/TuhfahZahidahShamsuddinMFS2014.pdf application/pdf en public http://dms.library.utm.my:8080/vital/access/manager/Repository/vital:79467?public=true masters Universiti Teknologi Malaysia, Faculty of Science Faculty of Science
institution	Universiti Teknologi Malaysia
collection	UTM Institutional Repository
language	English
topic	HF Commerce
spellingShingle	HF Commerce Shamsuddin, Tuhfah Zahidah Investigation on packaging material of counterfeit Panadol variants and Creobic cream by non-destructive tests
description	The World Health Organization (WHO) has defined counterfeit drugs as those which are “deliberately mislabelled with respect to identity and/or source”. Packaging materials are ubiquitous and manufacturers are able to obtain them from multiples of supplier. That is the reason for the unfeasible confiscation. There are a few methods used to detect counterfeit products through its packaging: visual inspection (visible light) and other optical methods such as infrared and ultraviolet analysis as well as pattern recognition. The objective of this study is to differentiate the features on the packaging material found from the original and the counterfeit of the same fast-moving pharmaceutical products. There are four different product packaging investigated obtained through over-the-counter purchase, from the complainant or seized by the authority. Firstly, examination is carried out on the direct paperboard packaging by comparison; physical examination on the basic properties (viz. dimension, thickness and prints), microscopic, optical character recognition (OCR) and near infrared analysis. Then, further investigation on the information printed and hologram serial number was done. Determination of the originality of the products upon procurement was done through authenticating the hologram. Microscopic examination on the printed paperboard exhibited consistent printing effect for all of the counterfeit and the genuine ones. Results on OCR for certain parts of the prints show constant difference between the original and counterfeit. However, the IR results indicated that such differences may prove inconsistent and hence unreliable to be used for comparison. In conclusion, the counterfeit pharmaceutical packaging may be distinguished from the genuine ones through physical examination of its basic properties, microscopic observation and OCR.
format	Thesis
qualification_level	Master's degree
author	Shamsuddin, Tuhfah Zahidah
author_facet	Shamsuddin, Tuhfah Zahidah
author_sort	Shamsuddin, Tuhfah Zahidah
title	Investigation on packaging material of counterfeit Panadol variants and Creobic cream by non-destructive tests
title_short	Investigation on packaging material of counterfeit Panadol variants and Creobic cream by non-destructive tests
title_full	Investigation on packaging material of counterfeit Panadol variants and Creobic cream by non-destructive tests
title_fullStr	Investigation on packaging material of counterfeit Panadol variants and Creobic cream by non-destructive tests
title_full_unstemmed	Investigation on packaging material of counterfeit Panadol variants and Creobic cream by non-destructive tests
title_sort	investigation on packaging material of counterfeit panadol variants and creobic cream by non-destructive tests
granting_institution	Universiti Teknologi Malaysia, Faculty of Science
granting_department	Faculty of Science
publishDate	2014
url	http://eprints.utm.my/id/eprint/48496/1/TuhfahZahidahShamsuddinMFS2014.pdf
_version_	1747817404565553152

Investigation on packaging material of counterfeit Panadol variants and Creobic cream by non-destructive tests

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