Arterial hemodynamics in patent ductus arteriosus stenting

Cyanotic congenital heart disease (CHD) is the condition when insufficient blood transported throughout the whole body due to anomalies of blood vessels or heart. Hence, the procedure of maintaing the patency of ductus arteriosus were introduced where the stent is implanted at ductus arteriosus that...

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Main Author:	Jamalruhanordin, Fara Lyana
Format:	Thesis
Language:	English
Published:	2015
Subjects:	R Medicine (General)
Online Access:	http://eprints.utm.my/id/eprint/53856/1/FaraLyanaJamalruhanordinMFBME2015.pdf
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id	my-utm-ep.53856
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spelling	my-utm-ep.538562020-09-08T08:03:25Z Arterial hemodynamics in patent ductus arteriosus stenting 2015-07 Jamalruhanordin, Fara Lyana R Medicine (General) Cyanotic congenital heart disease (CHD) is the condition when insufficient blood transported throughout the whole body due to anomalies of blood vessels or heart. Hence, the procedure of maintaing the patency of ductus arteriosus were introduced where the stent is implanted at ductus arteriosus that should be closed naturally within 48 hours after the birth. The main purpose of this study is to investigate the hemodyamic effect of patent ductus arteriosus (PDA) after different types of stent design were implanted. Three different types of commercial stent design were used in this study: Closed Cell V stent, Palmaz-Schatz stent and Type One stent. The hemodynamic effect were investigated numerically via computational fluid dynamics by using ANSYS 14.0 software. Three hemodynamics variables were analysed in this study which are wall shear stress (WSS), oscillatory shear index (OSI) and relative residence time (RRT). Each stent affect the hemodynamic within PDA differently. The higher percentage of TAWSS exposed in range of 0.5 Pa to 2 Pa is better shown by Closed Cell V stent with 25.4%. Type One stent shown a good result in OSI which has high percentages exposed below 0.2 with the value of 34%. Palmaz-Schatz stent present a preferable results in both WSS low, 1.2% (low the better) and RRT within range of 10 Pa^-1 at 97.7%. Thus, this study can be useful in stent selection for PDA stenting. 2015-07 Thesis http://eprints.utm.my/id/eprint/53856/ http://eprints.utm.my/id/eprint/53856/1/FaraLyanaJamalruhanordinMFBME2015.pdf application/pdf en public http://dms.library.utm.my:8080/vital/access/manager/Repository/vital:85894 masters Universiti Teknologi Malaysia, Faculty of Biosciences and Medical Engineering Faculty of Biosciences and Medical Engineering
institution	Universiti Teknologi Malaysia
collection	UTM Institutional Repository
language	English
topic	R Medicine (General)
spellingShingle	R Medicine (General) Jamalruhanordin, Fara Lyana Arterial hemodynamics in patent ductus arteriosus stenting
description	Cyanotic congenital heart disease (CHD) is the condition when insufficient blood transported throughout the whole body due to anomalies of blood vessels or heart. Hence, the procedure of maintaing the patency of ductus arteriosus were introduced where the stent is implanted at ductus arteriosus that should be closed naturally within 48 hours after the birth. The main purpose of this study is to investigate the hemodyamic effect of patent ductus arteriosus (PDA) after different types of stent design were implanted. Three different types of commercial stent design were used in this study: Closed Cell V stent, Palmaz-Schatz stent and Type One stent. The hemodynamic effect were investigated numerically via computational fluid dynamics by using ANSYS 14.0 software. Three hemodynamics variables were analysed in this study which are wall shear stress (WSS), oscillatory shear index (OSI) and relative residence time (RRT). Each stent affect the hemodynamic within PDA differently. The higher percentage of TAWSS exposed in range of 0.5 Pa to 2 Pa is better shown by Closed Cell V stent with 25.4%. Type One stent shown a good result in OSI which has high percentages exposed below 0.2 with the value of 34%. Palmaz-Schatz stent present a preferable results in both WSS low, 1.2% (low the better) and RRT within range of 10 Pa^-1 at 97.7%. Thus, this study can be useful in stent selection for PDA stenting.
format	Thesis
qualification_level	Master's degree
author	Jamalruhanordin, Fara Lyana
author_facet	Jamalruhanordin, Fara Lyana
author_sort	Jamalruhanordin, Fara Lyana
title	Arterial hemodynamics in patent ductus arteriosus stenting
title_short	Arterial hemodynamics in patent ductus arteriosus stenting
title_full	Arterial hemodynamics in patent ductus arteriosus stenting
title_fullStr	Arterial hemodynamics in patent ductus arteriosus stenting
title_full_unstemmed	Arterial hemodynamics in patent ductus arteriosus stenting
title_sort	arterial hemodynamics in patent ductus arteriosus stenting
granting_institution	Universiti Teknologi Malaysia, Faculty of Biosciences and Medical Engineering
granting_department	Faculty of Biosciences and Medical Engineering
publishDate	2015
url	http://eprints.utm.my/id/eprint/53856/1/FaraLyanaJamalruhanordinMFBME2015.pdf
_version_	1747817643189993472

Arterial hemodynamics in patent ductus arteriosus stenting

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