Evaluation of Acalypha indica extracts for antioxidant and antibacterial activities

For centuries, medicinal plants are being used as remedy for various ailments throughout the globe. The study was conducted emphasizing on the antibacterial and antioxidant activities of several Acalypha indica extracts. The plant was divided to leaves and stem, whole plant and roots and extracted w...

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Main Author:	Ruslan, Nur Fathin
Format:	Thesis
Language:	English
Published:	2015
Subjects:	R Medicine (General)
Online Access:	http://eprints.utm.my/id/eprint/53974/1/NurFathinRuslanMFBME2015.pdf
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id	my-utm-ep.53974
record_format	uketd_dc
spelling	my-utm-ep.539742020-10-11T08:05:26Z Evaluation of Acalypha indica extracts for antioxidant and antibacterial activities 2015-10 Ruslan, Nur Fathin R Medicine (General) For centuries, medicinal plants are being used as remedy for various ailments throughout the globe. The study was conducted emphasizing on the antibacterial and antioxidant activities of several Acalypha indica extracts. The plant was divided to leaves and stem, whole plant and roots and extracted with hexane, methanol and ethanol by successive method. Antioxidant activity was measured by 2,2-diphenyl-1- picrylhydrazyl (DPPH) Radical Scavenging assay and found to be highest in the ethanolic root extract with IC50 of 206 µg/ml. The antibacterial activity screening of different extracts was conducted by using disc diffusion, minimum inhibition concentration (MIC) and minimum bactericidal concentration (MBC) against Escherichia coli, Staphylococcus aureus, Pseudomonas aeruginosa and Enterococcus faecalis. Hexane extracts from leaves and stem, whole plant and roots showed promising results against Enterococcus faecalis with high inhibition zone at 10 to 12 mm as compared to standard antibiotics, 6 to 10 mm. All extracts showed antibacterial activity with minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) values in the range from 60 to 15 mg/ml. This study concludes that A. indica explicit antioxidant and antibacterial activities may be potential for pharmaceuticals, cosmeceuticals, nutraceuticals, medical and food industry. 2015-10 Thesis http://eprints.utm.my/id/eprint/53974/ http://eprints.utm.my/id/eprint/53974/1/NurFathinRuslanMFBME2015.pdf application/pdf en public http://dms.library.utm.my:8080/vital/access/manager/Repository/vital:85456 masters Universiti Teknologi Malaysia, Faculty of Biosciences and Medical Engineering Faculty of Biosciences and Medical Engineering
institution	Universiti Teknologi Malaysia
collection	UTM Institutional Repository
language	English
topic	R Medicine (General)
spellingShingle	R Medicine (General) Ruslan, Nur Fathin Evaluation of Acalypha indica extracts for antioxidant and antibacterial activities
description	For centuries, medicinal plants are being used as remedy for various ailments throughout the globe. The study was conducted emphasizing on the antibacterial and antioxidant activities of several Acalypha indica extracts. The plant was divided to leaves and stem, whole plant and roots and extracted with hexane, methanol and ethanol by successive method. Antioxidant activity was measured by 2,2-diphenyl-1- picrylhydrazyl (DPPH) Radical Scavenging assay and found to be highest in the ethanolic root extract with IC50 of 206 µg/ml. The antibacterial activity screening of different extracts was conducted by using disc diffusion, minimum inhibition concentration (MIC) and minimum bactericidal concentration (MBC) against Escherichia coli, Staphylococcus aureus, Pseudomonas aeruginosa and Enterococcus faecalis. Hexane extracts from leaves and stem, whole plant and roots showed promising results against Enterococcus faecalis with high inhibition zone at 10 to 12 mm as compared to standard antibiotics, 6 to 10 mm. All extracts showed antibacterial activity with minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) values in the range from 60 to 15 mg/ml. This study concludes that A. indica explicit antioxidant and antibacterial activities may be potential for pharmaceuticals, cosmeceuticals, nutraceuticals, medical and food industry.
format	Thesis
qualification_level	Master's degree
author	Ruslan, Nur Fathin
author_facet	Ruslan, Nur Fathin
author_sort	Ruslan, Nur Fathin
title	Evaluation of Acalypha indica extracts for antioxidant and antibacterial activities
title_short	Evaluation of Acalypha indica extracts for antioxidant and antibacterial activities
title_full	Evaluation of Acalypha indica extracts for antioxidant and antibacterial activities
title_fullStr	Evaluation of Acalypha indica extracts for antioxidant and antibacterial activities
title_full_unstemmed	Evaluation of Acalypha indica extracts for antioxidant and antibacterial activities
title_sort	evaluation of acalypha indica extracts for antioxidant and antibacterial activities
granting_institution	Universiti Teknologi Malaysia, Faculty of Biosciences and Medical Engineering
granting_department	Faculty of Biosciences and Medical Engineering
publishDate	2015
url	http://eprints.utm.my/id/eprint/53974/1/NurFathinRuslanMFBME2015.pdf
_version_	1747817665248886784

Evaluation of Acalypha indica extracts for antioxidant and antibacterial activities

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