Optimization of SWIETENIA MAHAGONI seed in supercritical carbon dioxide extraction

Supercritical carbon dioxide extraction has been used for extraction of essential oil from Swietenia mahagoni seed. The effect of different particle sizes on diffusivity coefficients, D (m2/s) were studied by applying second Fick’s law of diffusion proposed by Crank. Particle size of 710 µm showed t...

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Main Author:	Bakeri, Nor Asyiqin
Format:	Thesis
Language:	English
Published:	2017
Subjects:	TP Chemical technology
Online Access:	http://eprints.utm.my/id/eprint/78314/1/NorAsyiqinBakeriMFChE2017.pdf
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spelling	my-utm-ep.783142018-08-26T04:53:17Z Optimization of SWIETENIA MAHAGONI seed in supercritical carbon dioxide extraction 2017-03 Bakeri, Nor Asyiqin TP Chemical technology Supercritical carbon dioxide extraction has been used for extraction of essential oil from Swietenia mahagoni seed. The effect of different particle sizes on diffusivity coefficients, D (m2/s) were studied by applying second Fick’s law of diffusion proposed by Crank. Particle size of 710 µm showed the highest D of 3.1 x 10-12 m2/s. Gas compression at pressure of 30 MPa and temperature of 60 oC on seeds caused swelling thus allowed faster diffusion of carbon dioxide through porous structure of Swietenia mahagoni seed. For optimization of Swietenia mahagoni seed oil extraction, a three-level factorial design in response surface methodology was used to analysis the effect of pressure (20 – 30 MPa) and temperature (40 - 60 oC) on extraction oil yield. The highest extraction oil yield of 29.70% was obtained at pressure of 30 MPa and temperature of 40 oC. This explained that increased pressure and low temperature increased the carbon dioxide density. Thus, higher solute bonding in solvent phase and consequently higher the extraction yield was obtained. Qualitative phytochemical analysis showed the presense of alkaloid, saponin, triterpenoid, phenolic hydroquinone and tannin but absense of flavonoid. Toxicity test of Swietenia mahagoni seed extract using 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide assay on human skin fibroblast cell (HSF 1184) showed cell viability above 80%. The result showed that Swietenia mahagoni seed extracts at studied concentrations (10, 1, 0.1, 0.01, 0.001, 0.0001 mg/ml) are non toxic. 2017-03 Thesis http://eprints.utm.my/id/eprint/78314/ http://eprints.utm.my/id/eprint/78314/1/NorAsyiqinBakeriMFChE2017.pdf application/pdf en public http://dms.library.utm.my:8080/vital/access/manager/Repository/vital:105145 masters Universiti Teknologi Malaysia, Faculty of Chemical Engineering Faculty of Chemical Engineering
institution	Universiti Teknologi Malaysia
collection	UTM Institutional Repository
language	English
topic	TP Chemical technology
spellingShingle	TP Chemical technology Bakeri, Nor Asyiqin Optimization of SWIETENIA MAHAGONI seed in supercritical carbon dioxide extraction
description	Supercritical carbon dioxide extraction has been used for extraction of essential oil from Swietenia mahagoni seed. The effect of different particle sizes on diffusivity coefficients, D (m2/s) were studied by applying second Fick’s law of diffusion proposed by Crank. Particle size of 710 µm showed the highest D of 3.1 x 10-12 m2/s. Gas compression at pressure of 30 MPa and temperature of 60 oC on seeds caused swelling thus allowed faster diffusion of carbon dioxide through porous structure of Swietenia mahagoni seed. For optimization of Swietenia mahagoni seed oil extraction, a three-level factorial design in response surface methodology was used to analysis the effect of pressure (20 – 30 MPa) and temperature (40 - 60 oC) on extraction oil yield. The highest extraction oil yield of 29.70% was obtained at pressure of 30 MPa and temperature of 40 oC. This explained that increased pressure and low temperature increased the carbon dioxide density. Thus, higher solute bonding in solvent phase and consequently higher the extraction yield was obtained. Qualitative phytochemical analysis showed the presense of alkaloid, saponin, triterpenoid, phenolic hydroquinone and tannin but absense of flavonoid. Toxicity test of Swietenia mahagoni seed extract using 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide assay on human skin fibroblast cell (HSF 1184) showed cell viability above 80%. The result showed that Swietenia mahagoni seed extracts at studied concentrations (10, 1, 0.1, 0.01, 0.001, 0.0001 mg/ml) are non toxic.
format	Thesis
qualification_level	Master's degree
author	Bakeri, Nor Asyiqin
author_facet	Bakeri, Nor Asyiqin
author_sort	Bakeri, Nor Asyiqin
title	Optimization of SWIETENIA MAHAGONI seed in supercritical carbon dioxide extraction
title_short	Optimization of SWIETENIA MAHAGONI seed in supercritical carbon dioxide extraction
title_full	Optimization of SWIETENIA MAHAGONI seed in supercritical carbon dioxide extraction
title_fullStr	Optimization of SWIETENIA MAHAGONI seed in supercritical carbon dioxide extraction
title_full_unstemmed	Optimization of SWIETENIA MAHAGONI seed in supercritical carbon dioxide extraction
title_sort	optimization of swietenia mahagoni seed in supercritical carbon dioxide extraction
granting_institution	Universiti Teknologi Malaysia, Faculty of Chemical Engineering
granting_department	Faculty of Chemical Engineering
publishDate	2017
url	http://eprints.utm.my/id/eprint/78314/1/NorAsyiqinBakeriMFChE2017.pdf
_version_	1747817958980190208

Optimization of SWIETENIA MAHAGONI seed in supercritical carbon dioxide extraction

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