Study of MEP response of transcranial magnetic stimulation in multiple muscles on healthy subjects

Transcranial Magnetic Stimulation (TMS) is a device that is used to stimulate the brain for diagnostic or therapeutic purpose. It is usually used in post stroke treatment, depression treatment and pain control. Myriad research was done on the Muscle Evoked Potential (MEP) of the muscles when the TMS...

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Main Author:	Mohd. Zakaria, Mohamad Nur Faiz
Format:	Thesis
Language:	English
Published:	2017
Subjects:	QH301 Biology
Online Access:	http://eprints.utm.my/id/eprint/78808/1/MohamadNurFaizMFBME2017.pdf
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spelling	my-utm-ep.788082018-09-17T04:13:04Z Study of MEP response of transcranial magnetic stimulation in multiple muscles on healthy subjects 2017-06 Mohd. Zakaria, Mohamad Nur Faiz QH301 Biology Transcranial Magnetic Stimulation (TMS) is a device that is used to stimulate the brain for diagnostic or therapeutic purpose. It is usually used in post stroke treatment, depression treatment and pain control. Myriad research was done on the Muscle Evoked Potential (MEP) of the muscles when the TMS had been applied to the motor cortex of the brain. Most studies that involve single muscle are only either on the hand or leg. There are also studies involve multiple muscles for different goals and different targeted muscles. This study will focus on obtaining the optimum motor threshold that are out from the TMS to the motor cortex in order to obtain the MEP amplitude of the targeted muscles. The signals of the EMG of the APB, FCR and ADM were recorded using Bioradio analysed in Matlab by filter algorithm consists of High Pass filter and Notch filter. From the project, the MEP of the selected muscle were obtained with APB muscles with 0.12 mV, FCR is 0.11 mV and for muscle of ADM is 0.12 mV. The APB and ADM that have high MEP shows that it is easily stimulated by the TMS compare to FCR. The Motor Threshold that was obtained through this project is enough to make the targeted muscles responses of 64% from the full power of the TMS. This Motor Threshold can be used as the benchmark for other research on the minimum level of power needed by TMS. This minimum level power given to the subject is needed to study the reponse of three muscles involved. 2017-06 Thesis http://eprints.utm.my/id/eprint/78808/ http://eprints.utm.my/id/eprint/78808/1/MohamadNurFaizMFBME2017.pdf application/pdf en public http://dms.library.utm.my:8080/vital/access/manager/Repository/vital:109601 masters Universiti Teknologi Malaysia, Faculty of Biosciences and Medical Engineering Faculty of Biosciences and Medical Engineering
institution	Universiti Teknologi Malaysia
collection	UTM Institutional Repository
language	English
topic	QH301 Biology
spellingShingle	QH301 Biology Mohd. Zakaria, Mohamad Nur Faiz Study of MEP response of transcranial magnetic stimulation in multiple muscles on healthy subjects
description	Transcranial Magnetic Stimulation (TMS) is a device that is used to stimulate the brain for diagnostic or therapeutic purpose. It is usually used in post stroke treatment, depression treatment and pain control. Myriad research was done on the Muscle Evoked Potential (MEP) of the muscles when the TMS had been applied to the motor cortex of the brain. Most studies that involve single muscle are only either on the hand or leg. There are also studies involve multiple muscles for different goals and different targeted muscles. This study will focus on obtaining the optimum motor threshold that are out from the TMS to the motor cortex in order to obtain the MEP amplitude of the targeted muscles. The signals of the EMG of the APB, FCR and ADM were recorded using Bioradio analysed in Matlab by filter algorithm consists of High Pass filter and Notch filter. From the project, the MEP of the selected muscle were obtained with APB muscles with 0.12 mV, FCR is 0.11 mV and for muscle of ADM is 0.12 mV. The APB and ADM that have high MEP shows that it is easily stimulated by the TMS compare to FCR. The Motor Threshold that was obtained through this project is enough to make the targeted muscles responses of 64% from the full power of the TMS. This Motor Threshold can be used as the benchmark for other research on the minimum level of power needed by TMS. This minimum level power given to the subject is needed to study the reponse of three muscles involved.
format	Thesis
qualification_level	Master's degree
author	Mohd. Zakaria, Mohamad Nur Faiz
author_facet	Mohd. Zakaria, Mohamad Nur Faiz
author_sort	Mohd. Zakaria, Mohamad Nur Faiz
title	Study of MEP response of transcranial magnetic stimulation in multiple muscles on healthy subjects
title_short	Study of MEP response of transcranial magnetic stimulation in multiple muscles on healthy subjects
title_full	Study of MEP response of transcranial magnetic stimulation in multiple muscles on healthy subjects
title_fullStr	Study of MEP response of transcranial magnetic stimulation in multiple muscles on healthy subjects
title_full_unstemmed	Study of MEP response of transcranial magnetic stimulation in multiple muscles on healthy subjects
title_sort	study of mep response of transcranial magnetic stimulation in multiple muscles on healthy subjects
granting_institution	Universiti Teknologi Malaysia, Faculty of Biosciences and Medical Engineering
granting_department	Faculty of Biosciences and Medical Engineering
publishDate	2017
url	http://eprints.utm.my/id/eprint/78808/1/MohamadNurFaizMFBME2017.pdf
_version_	1747818076343107584

Study of MEP response of transcranial magnetic stimulation in multiple muscles on healthy subjects

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