Penetap tulang besi-keluli tahan karat terbiodegradasi menggunakan kaedah kimpalan geseran

For the treatments of bone fracture, surgery will be conducted by installing the implant to maintain the proper position of fractured bone until the bone has completely joined. The implant removal surgery have been discussed till now due to the complication cases, the reaction of rejection from pati...

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Main Author: Nasution, Ahmad Kafrawi
Format: Thesis
Language:English
Published: 2017
Subjects:
Online Access:http://eprints.utm.my/id/eprint/81781/1/AhmadKafrawiNasutionPFBME2017.pdf
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spelling my-utm-ep.817812019-09-29T10:53:49Z Penetap tulang besi-keluli tahan karat terbiodegradasi menggunakan kaedah kimpalan geseran 2017-03 Nasution, Ahmad Kafrawi TP Chemical technology For the treatments of bone fracture, surgery will be conducted by installing the implant to maintain the proper position of fractured bone until the bone has completely joined. The implant removal surgery have been discussed till now due to the complication cases, the reaction of rejection from patient body and the risks of refracture. This research introduced a new system for bone-fracture screw application whereby it can minimise the procedure of bone fracture surgery and it enable to avoid the occurrence of bone refracture. The screw was made from two different materials which are SS316L (inert metal) and pure iron (biodegradable metal). In this system, the SS316L part will be removed while the pure iron will be remained in the bone. The combination of these two different metals was performed using friction welding technique. The welding joint of SS316L and pure Fe was successfully produced and then the screw product was also fabricated. The result from cell viability test of Normal Human Osteoblasts (NHOst) cells have shown that all the welded zones were biocompatible and have not induced any toxicity towards the cells. The concentration of the iron ion from the immersion corrosion test was 0.002375 mg/ml and this value is still below the safe concentration level of 0.050 mg/ml. The strength to pull out the screw from the cow bone tested ex vivo was 3879 ± 248 N while the pull-out failure only occurred on the cow bone (not on the screw). Further researches could be performed in future in order to know the effect of Fe ion distribution towards the organs of animal model through histology assessment. 2017-03 Thesis http://eprints.utm.my/id/eprint/81781/ http://eprints.utm.my/id/eprint/81781/1/AhmadKafrawiNasutionPFBME2017.pdf application/pdf en public http://dms.library.utm.my:8080/vital/access/manager/Repository/vital:126319 phd doctoral Universiti Teknologi Malaysia, Faculty of Biosciences and Medical Engineering Faculty of Biosciences and Medical Engineering
institution Universiti Teknologi Malaysia
collection UTM Institutional Repository
language English
topic TP Chemical technology
spellingShingle TP Chemical technology
Nasution, Ahmad Kafrawi
Penetap tulang besi-keluli tahan karat terbiodegradasi menggunakan kaedah kimpalan geseran
description For the treatments of bone fracture, surgery will be conducted by installing the implant to maintain the proper position of fractured bone until the bone has completely joined. The implant removal surgery have been discussed till now due to the complication cases, the reaction of rejection from patient body and the risks of refracture. This research introduced a new system for bone-fracture screw application whereby it can minimise the procedure of bone fracture surgery and it enable to avoid the occurrence of bone refracture. The screw was made from two different materials which are SS316L (inert metal) and pure iron (biodegradable metal). In this system, the SS316L part will be removed while the pure iron will be remained in the bone. The combination of these two different metals was performed using friction welding technique. The welding joint of SS316L and pure Fe was successfully produced and then the screw product was also fabricated. The result from cell viability test of Normal Human Osteoblasts (NHOst) cells have shown that all the welded zones were biocompatible and have not induced any toxicity towards the cells. The concentration of the iron ion from the immersion corrosion test was 0.002375 mg/ml and this value is still below the safe concentration level of 0.050 mg/ml. The strength to pull out the screw from the cow bone tested ex vivo was 3879 ± 248 N while the pull-out failure only occurred on the cow bone (not on the screw). Further researches could be performed in future in order to know the effect of Fe ion distribution towards the organs of animal model through histology assessment.
format Thesis
qualification_name Doctor of Philosophy (PhD.)
qualification_level Doctorate
author Nasution, Ahmad Kafrawi
author_facet Nasution, Ahmad Kafrawi
author_sort Nasution, Ahmad Kafrawi
title Penetap tulang besi-keluli tahan karat terbiodegradasi menggunakan kaedah kimpalan geseran
title_short Penetap tulang besi-keluli tahan karat terbiodegradasi menggunakan kaedah kimpalan geseran
title_full Penetap tulang besi-keluli tahan karat terbiodegradasi menggunakan kaedah kimpalan geseran
title_fullStr Penetap tulang besi-keluli tahan karat terbiodegradasi menggunakan kaedah kimpalan geseran
title_full_unstemmed Penetap tulang besi-keluli tahan karat terbiodegradasi menggunakan kaedah kimpalan geseran
title_sort penetap tulang besi-keluli tahan karat terbiodegradasi menggunakan kaedah kimpalan geseran
granting_institution Universiti Teknologi Malaysia, Faculty of Biosciences and Medical Engineering
granting_department Faculty of Biosciences and Medical Engineering
publishDate 2017
url http://eprints.utm.my/id/eprint/81781/1/AhmadKafrawiNasutionPFBME2017.pdf
_version_ 1747818412551176192