The age-structured stochastics-(I (C) I (A))-R Model for acute and chronic hepatitis B disease mapping in Malaysia (IR)
The main objective of this study is to introduce an alternative method to estimate the relative risk for acute and chronic hepatitis B based on the age group. This study considers the transmission of the disease in the S-(I(C) I(A))-R stochastic model and used it as the equation for relative risk. I...
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| Main Author: | |
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| Format: | thesis |
| Language: | eng |
| Published: |
2017
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| Subjects: | |
| Online Access: | https://ir.upsi.edu.my/detailsg.php?det=210 |
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| Summary: | The main objective of this study is to introduce an alternative method to estimate the relative risk for acute and chronic hepatitis B based on the age group. This study considers the transmission of the disease in the S-(I(C) I(A))-R stochastic model and used it as the equation for relative risk. In this study, the SIIR model related with hepatitis B have been revised and expanded to formed an the alternative S-(I(C) I(A))-R model according to the age structure. Model S-(I(C) I(A))-R are based on the age structure proposed used to estimate the relative risk for acute and chronic hepatitis B in Malaysia. Results are compared with the general method used to estimate the relative risk by using SMR and Poisson-gamma model. Results of the analysis of data from Malaysia showed that, for acute hepatitis B, children identified as having a higher risk compared to adults. While for chronic hepatitis B, adults identified as having a higher risk compared to children. This decision is based on the disease risk map produced using age-structured S-(I(C) I(A))-R stochastic model. In conclusion, the alternative method to estimate the relative risk of acute and chronic hepatitis B provide are a better estimated than the SMR and Poisson-Gamma, which did not have a zero relative risk for a specific area and each state has a relative risk that are more accurately summarized in the age-structured S-(I(C) I(A))-R model. As implication, the alternative methods of disease risk map proposed in this study can be used as reference by the authorities or a medical officer in the control of hepatitis B acute and chronic in Malaysia. |
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