Studies on essential oils, phytochemicals and antioxidant activity of Magnolia candollii H.Keng and Magnolia alba DC.(MAGNOLIACEAE)
<p>The purpose of this study was to investigate the essential oils, phytochemicals, and</p><p>antioxidant activity of Magnolia candollii and Magnolia alba (Magnoliaceae). The</p><p>essential oils were obtained via hydrodistillatio...
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| Format: | thesis |
| Language: | eng |
| Published: |
2022
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| Subjects: | |
| Online Access: | https://ir.upsi.edu.my/detailsg.php?det=9696 |
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| Summary: | <p>The purpose of this study was to investigate the essential oils, phytochemicals, and</p><p>antioxidant activity of Magnolia candollii and Magnolia alba (Magnoliaceae). The</p><p>essential oils were obtained via hydrodistillation technique and their chemical</p><p>compositions were determined by gas chromatography-flame ionization detection</p><p>(GC-FID) and gas chromatography-mass spectrometry (GC-MS). The phytochemicals</p><p>were isolated using chromatography techniques and their structures were confirmed</p><p>by spectroscopic data and comparison with literature. The antioxidant activity was</p><p>determined through total phenolic content and DPPH free radical scavenging assay.</p><p>The study showed that the essential oil of M. candollii consists of -pinene (29.7%),</p><p>elemol (10.2%), -pinene (8.5%), -caryophyllene (7.2%), -terpineol (7.0%), and</p><p>guaiol (5.4%). In addition, the major components of essential oil from M. alba were</p><p>linalool (65.4%), -caryophyllene (6.7%), and (E)-nerolidol (5.2%). Isolation and</p><p>purification of M. candollii bark and M. alba leaf extracts yielded seven</p><p>phytochemicals identified as licarin A, squalene, parthenolide, vanillin, stigmasterol</p><p>acetate, friedelin, and -sitosterol. Besides, linalool was successfully isolated from M.</p><p>alba leaf essential oil. The methanol extract of M. candollii showed the highest</p><p>antioxidant activity with phenolic content value as 380.0 mg GAE/g and 77.2%</p><p>inhibition in the DPPH free radical scavenging assay. Licarin A demonstrated the</p><p>highest antioxidant activity among the isolated compounds with percentage inhibition</p><p>of 72.0% in the DPPH assay. In conclusion, the essential oils of M. candollii bark and</p><p>M. alba leaf contain oxygenated monoterpenes and monoterpene hydrocarbons as</p><p>principal components, respectively. Meanwhile, the phytochemical study of both plant</p><p>extracts led to identification of different classes of natural compounds including</p><p>neolignan, sesquiterpene lactone, phenolic, and terpenes. The study has significant</p><p>implication on natural product research regarding essential oils and phytochemicals</p><p>with promising antioxidant activity as well as their applications in the pharmaceutical</p><p>industries.</p> |
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