Essential oils, phytochemistry and antioxidant activity of Syzygium pyrifolium (Blume) DC. (MYRTACEAE)
<p>This study aims to identify the essential oils composition, phytochemicals, and</p><p>antioxidant activity of Syzygium pyrifolium (Blume) DC. leaves and bark extracts. The</p><p>essential oils were obtained using hydrodistillat...
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| Format: | thesis |
| Language: | eng |
| Published: |
2022
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| Subjects: | |
| Online Access: | https://ir.upsi.edu.my/detailsg.php?det=9754 |
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| Summary: | <p>This study aims to identify the essential oils composition, phytochemicals, and</p><p>antioxidant activity of Syzygium pyrifolium (Blume) DC. leaves and bark extracts. The</p><p>essential oils were obtained using hydrodistillation technique and their chemical</p><p>compositions were determined by gas chromatography and gas chromatography-mass</p><p>spectrometry. Phytochemicals were separated using various chromatography</p><p>techniques and their structures were elucidated using infrared, nuclear magnetic</p><p>resonance, ultraviolet, and mass spectrometry. Antioxidant activity of the essential</p><p>oils, extracts, and selected phytochemicals was determined using the total phenolic</p><p>content and free radical scavenging assay. Results showed that S. pyrifolium leaf oil</p><p>mainly consists of geraniol (73.8%), -pinene (7.0%), -pinene (5.7%), and (E)--</p><p>ocimene (4.5%). Geraniol was successfully separated from the leaf oil as a pure</p><p>compound. The bark oil contains cuparene (7.2%), -elemene (6.8%), longifolene</p><p>(5.6%) and -terpineol (4.7%) as major components. Seven compounds were also</p><p>separated from the leaf and bark extracts of S. pyrifolium and successfully identified</p><p>as 5-hydroxy-3,7,4-trimethoxyflavone, 5-hydroxy-3,7,3,4-tetramethoxyflavone, 5,4-</p><p>dihydroxy-3,7,3-trimethoxyflavone, 5-hydroxy-6,7,4-trimethoxyflavone, 4,5,7-</p><p>trimethoxyflavone, 5,7-dimethoxyflavone, and 3,4,5-trihydroxybenzoic acid. The bark</p><p>methanolic extract exhibited the highest total phenolic content with gallic acid</p><p>equivalent to 490 mg/g extract. Meanwhile, leaf and bark methanolic extracts showed</p><p>strong antioxidant activity in the free radical scavenging assay with percentage</p><p>inhibition of 88.4% and 89.9%, respectively. In conclusion, leaf and bark oils of S.</p><p>pyrifolium consist of oxygenated monoterpenes and sesquiterpene hydrocarbons as</p><p>major group components. In addition, leaves and bark methanolic extracts mainly</p><p>contain flavonoids and phenolic compounds which exhibited strong antioxidant</p><p>activity. This study implies that extracts of S. pyrifolium have potential to prevent free</p><p>radical harmful effects and may protect against various cardiovascular and</p><p>inflammatory diseases.</p> |
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