The study of sperm energy metabolism measured using 13C magnetic resonance spectroscopy
Studying energy metabolism in sperm may be helpful in understanding the relationship between poor sperm motility and infertility. Sperm motility is fuelled by Adenosine triphosphate (ATP). Main ATP related production pathways are anaerobic glycolysis and oxidative phosphorylation (OXPHOS). These pat...
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| التنسيق: | أطروحة كتاب |
| اللغة: | English |
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جدول المحتويات:
- 1. Introduction to spermatozoa and MRS
- 2. Materials and methods
- 3. Preliminary experiments
- 4. The effect of metabolic inhibitors on sperm metabolism and vitality
- 5. Effects of temperature, labelled substrate and inhibitors
- 6. Sperm metabolism measured using hyperpolarised 2-13C pyruvate
- 7. The effect of oxygen concentration on sperm metabolism
- 8. General discussion, conclusions and future work