Effects of ticlopidine on metoprolol pharmacokinetics in major CYP2D6 genotypes within Malaysian subjects with cardiovascular diseases /

Effects of ticlopidine on metoprolol pharmacokinetics in major CYP2D6 genotypes within Malaysian subjects with cardiovascular diseases /

Ticlopidine is used as an anti-platelet drug in patients with ischaemic heart disease. An in vitro study suggested that ticlopidine inhibited CYP2D6 and the widely used antianginal metoprolol is metabolized by this polymorphic enzyme. The objective of this study to investigate the effect of ticlopid...

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書目詳細資料
主要作者:	Wan Mohd Azizi bin Wan Sulaiman
格式:	Thesis
語言:	English
出版:	Kuantan, Pahang : Kulliyyah of Medicine, International Islamic University Malaysia, 2010
主題:	Ticlopidine > Testing Cytochrome P-450 CYP2D6 Pharmacokinetics Cardiovascular system > Diseases Theses, IIUM local
在線閱讀:	Click here to view 1st 24 pages of the thesis. Members can view fulltext at the specified PCs in the library.
標簽:	添加標簽沒有標簽, 成為第一個標記此記錄!

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