Neuroprotective effect and Molecular Mechanisms of action of Magnesium Acetyltaurate against NMDA-Induced Retinal Injury in rats: focus on calcium regulated proteins / Azliana Jusnida Ahmad Jafri
The excitotoxicity refers to excessive calcium influx intracellularly due to stimulation of glutamate receptors particularly the NMDA subtypes. This triggers apoptosis via calpain, calcineurin, CaMKII activation and cabin 1 inhibition. Altered expression of these Ca2+ regulated proteins cause increa...
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| Main Author: | |
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| Format: | Thesis |
| Language: | English |
| Published: |
2020
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| Subjects: | |
| Online Access: | https://ir.uitm.edu.my/id/eprint/63935/1/63935.pdf |
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