Malaysian fungal endophytes as a source of bioactive metabolites / Hamidah Abu Bakar

Endophytes are microorganisms that reside within plants and appear as an enormous yet relatively untapped source of natural product. The objectives of this study include isolation of endophytes from medicinal plants, determination of antimicrobial and antitumour activity of cultures extracts, identi...

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Main Author: Abu Bakar, Hamidah
Format: Thesis
Language:English
Published: 2009
Subjects:
Online Access:https://ir.uitm.edu.my/id/eprint/99364/1/99364.pdf
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spelling my-uitm-ir.993642024-12-11T04:50:29Z Malaysian fungal endophytes as a source of bioactive metabolites / Hamidah Abu Bakar 2009 Abu Bakar, Hamidah Metabolism Endophytes are microorganisms that reside within plants and appear as an enormous yet relatively untapped source of natural product. The objectives of this study include isolation of endophytes from medicinal plants, determination of antimicrobial and antitumour activity of cultures extracts, identification of the bioactive endophytes through morphological, biochemical and genetic characterization. A total number of 348 endophytes were isolated through surface sterilization from 24 local medicinal plants of the Kuala Pilah Rain Forest, Malaysia. For the antimicrobial test, a disc diffusion assay was employed and the endophytic crude extracts were tested against bacteria (Bacillus subtilis, Micrococcus luteus, Staphylococcus aureus and Escherichia coli) and fungi (Candida albicans, Aspergillus niger, and Saccharomyces cerevisiae). 2009 Thesis https://ir.uitm.edu.my/id/eprint/99364/ https://ir.uitm.edu.my/id/eprint/99364/1/99364.pdf text en public masters Universiti Teknologi MARA (UiTM) Faculty of Pharmacy
institution Universiti Teknologi MARA
collection UiTM Institutional Repository
language English
topic Metabolism
spellingShingle Metabolism
Abu Bakar, Hamidah
Malaysian fungal endophytes as a source of bioactive metabolites / Hamidah Abu Bakar
description Endophytes are microorganisms that reside within plants and appear as an enormous yet relatively untapped source of natural product. The objectives of this study include isolation of endophytes from medicinal plants, determination of antimicrobial and antitumour activity of cultures extracts, identification of the bioactive endophytes through morphological, biochemical and genetic characterization. A total number of 348 endophytes were isolated through surface sterilization from 24 local medicinal plants of the Kuala Pilah Rain Forest, Malaysia. For the antimicrobial test, a disc diffusion assay was employed and the endophytic crude extracts were tested against bacteria (Bacillus subtilis, Micrococcus luteus, Staphylococcus aureus and Escherichia coli) and fungi (Candida albicans, Aspergillus niger, and Saccharomyces cerevisiae).
format Thesis
qualification_level Master's degree
author Abu Bakar, Hamidah
author_facet Abu Bakar, Hamidah
author_sort Abu Bakar, Hamidah
title Malaysian fungal endophytes as a source of bioactive metabolites / Hamidah Abu Bakar
title_short Malaysian fungal endophytes as a source of bioactive metabolites / Hamidah Abu Bakar
title_full Malaysian fungal endophytes as a source of bioactive metabolites / Hamidah Abu Bakar
title_fullStr Malaysian fungal endophytes as a source of bioactive metabolites / Hamidah Abu Bakar
title_full_unstemmed Malaysian fungal endophytes as a source of bioactive metabolites / Hamidah Abu Bakar
title_sort malaysian fungal endophytes as a source of bioactive metabolites / hamidah abu bakar
granting_institution Universiti Teknologi MARA (UiTM)
granting_department Faculty of Pharmacy
publishDate 2009
url https://ir.uitm.edu.my/id/eprint/99364/1/99364.pdf
_version_ 1818588006674595840