Production of Pravastatin by Filamentous Fungi Isolated from Soil

Pravastatin is a clinically useful cholesterol-lowering agent, selectively inhibiting 3-hydroxy-3-methylglutaryl-coenzyme A reductase, the regulatory enzyme in cholesterol biosynthesis. Currently, industrial production of this statin is based on a two-step fermentation process: the initial productio...

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Bibliographic Details
Main Author: Emine, Seydametova
Format: Thesis
Published: 2013
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