Enzymatic Synthesis of 3-O-Acylbetulinic Acid Derivatives and Prediction of Acylation Using Response Surface Methodology and Artificial Neural Network Analyses
In this study, 3-O-acyl-betulinic acid derivatives were synthesized by the reaction of betulinic acid with various anhydrides using lipase as a biocatalyst in organic solvents. The reaction between betulinic acid and phthalic anhydride was chosen as the model reaction for optimization studies. Th...
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| Format: | Thesis |
| Language: | English English |
| Published: |
2010
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| Subjects: | |
| Online Access: | http://psasir.upm.edu.my/id/eprint/12441/1/FS_2010_26A.pdf |
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