Development, characterisation and translocation of valproic acid-encapsulated nanoemulsion across blood-brain barrier

Development, characterisation and translocation of valproic acid-encapsulated nanoemulsion across blood-brain barrier

Valproic acid (VPA) is a widely used antiepileptic drug (AED) for epilepsy especially in generalized and absence seizures. However, VPA has high plasma protein binding (90 % - 95 %) so only low amount of free VPA were able to reach the brain. An increase in therapeutic dose is not feasible as it wil...

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書目詳細資料
主要作者:	Tan, Suk Fei
格式:	Thesis
語言:	English
出版:	2017
主題:	Valproic Acid Blood-Brain Barrier
在線閱讀:	http://psasir.upm.edu.my/id/eprint/70689/1/FPSK%28P%29%202017%2013%20-%20IR.pdf
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