Metabolic and functional characterisation of adult skeletal muscle in down syndrome mouse model (Ts1CJe) for insights into hypotonia in human condition

Down syndrome (DS) is a genetic condition resulting from a partial or full triplication of human chromosome 21. In addition to intellectual disability, DS is frequently associated with hypotonia. However, little is known about its underlying mechanism. In this study, the trisomic Ts1Cje mouse, a DS...

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Bibliographic Details
Main Author: Lim, Chai Ling
Format: Thesis
Language:English
Published: 2017
Subjects:
Online Access:http://psasir.upm.edu.my/id/eprint/70910/1/FPSK%28M%29%202017%207%20-%20IR.pdf
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