Design, Synthesis And Characterization Of 4-Oxobutanoic Acid Analogues As Potential Human Hypoxia Inducible Factor (Hif) Prolyl Hydroxylase Domain 2 (Phd-2) Inhibitors

There is a widespread interest in developing the human hypoxia inducible factor (HIF) prolyl hydroxylase inhibitors for the treatment of ischemic/hypoxic diseases. In this study, a new series of 4-oxobutanoic acid analogues was investigated as potential HIF prolyl hydroxylase domain-2 (PHD-2) inhibi...

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Bibliographic Details
Main Author: Chong, Mui Phin
Format: Thesis
Language:English
Published: 2018
Subjects:
Online Access:http://eprints.usm.my/48190/1/CHONG%20MUI%20PHIN_hj.pdf
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