Iron Oxide Encapsulated Gold Colloidal Nanoparticle Via Rapid Sonochemical Method For Mri And Ct Imaging Application
Core@shell nanoparticles (Fe3O4@Au NPs) have multiple functions obtained in one stable entity and thus have been extensively investigated. Combining Fe3O4 and Au NPs in one core@shell nanostructure is a promising strategy for diagnostic biomedical applications. However, the conventional direct metho...
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my-usm-ep.520552022-03-28T07:07:55Z Iron Oxide Encapsulated Gold Colloidal Nanoparticle Via Rapid Sonochemical Method For Mri And Ct Imaging Application 2021-02 Dheyab, Mohammed Ali QC1 Physics (General) Core@shell nanoparticles (Fe3O4@Au NPs) have multiple functions obtained in one stable entity and thus have been extensively investigated. Combining Fe3O4 and Au NPs in one core@shell nanostructure is a promising strategy for diagnostic biomedical applications. However, the conventional direct methods for Fe3O4@Au NPs synthesis are laborious and time-consuming. Therefore, this study presents a facile and rapid sonochemical technique of synthesising Fe3O4@Au NPs with excellent physicochemical properties for magnetic resonance imaging (MRI) and computed tomography (CT) scan. The Au shell is coated on Fe3O4 NPs using a Vibra-Cell ultrasonic solid horn with tip size, frequency and power output of ½ inch, 20 kHz and 750 watts, respectively within 10 minutes. The targeted zeta potential of - 46.125 mV was achieved under the optimum conditions of 10 ml of HAuCl4, 30 ml of sodium citrate (SC) and sonication amplitude of 40%, which is consistent (about 99.2%) with the actual average zeta potential (- 45.8 mV). The stability and monodispersing of Fe3O4NPs improved following modification to Fe3O4@Au, as indicated by the increase in zeta potential from - 24.2 mV to - 45.8 mV. The saturation magnetization (Ms) value of Fe3O4 was 54 emu/g, while that of Fe3O4@Au NP is 38 emu/g. In general, the sonochemical method effectively synthesis highly stable and monodisperse Fe3O4@Au NPs with an average size of about 20 nm within 10 minutes. 2021-02 Thesis http://eprints.usm.my/52055/ http://eprints.usm.my/52055/1/MOHAMMED%20ALI%20DHEYAB.pdf application/pdf en public phd doctoral Perpustakaan Hamzah Sendut Pusat Pengajian Sains Fizik |
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Universiti Sains Malaysia |
| collection |
USM Institutional Repository |
| language |
English |
| topic |
QC1 Physics (General) |
| spellingShingle |
QC1 Physics (General) Dheyab, Mohammed Ali Iron Oxide Encapsulated Gold Colloidal Nanoparticle Via Rapid Sonochemical Method For Mri And Ct Imaging Application |
| description |
Core@shell nanoparticles (Fe3O4@Au NPs) have multiple functions obtained in one stable entity and thus have been extensively investigated. Combining Fe3O4 and Au NPs in one core@shell nanostructure is a promising strategy for diagnostic biomedical applications. However, the conventional direct methods for Fe3O4@Au NPs synthesis are laborious and time-consuming. Therefore, this study presents a facile and rapid sonochemical technique of synthesising Fe3O4@Au NPs with excellent physicochemical properties for magnetic resonance imaging (MRI) and computed tomography (CT) scan. The Au shell is coated on Fe3O4 NPs using a Vibra-Cell ultrasonic solid horn with tip size, frequency and power output of ½ inch, 20 kHz and 750 watts, respectively within 10 minutes. The targeted zeta potential of - 46.125 mV was achieved under the optimum conditions of 10 ml of HAuCl4, 30 ml of sodium citrate (SC) and sonication amplitude of 40%, which is consistent (about 99.2%) with the actual average zeta potential (- 45.8 mV). The stability and monodispersing of Fe3O4NPs improved following modification to Fe3O4@Au, as indicated by the increase in zeta potential from - 24.2 mV to - 45.8 mV. The saturation magnetization (Ms) value of Fe3O4 was 54 emu/g, while that of Fe3O4@Au NP is 38 emu/g. In general, the sonochemical method effectively synthesis highly stable and monodisperse Fe3O4@Au NPs with an average size of about 20 nm within 10 minutes. |
| format |
Thesis |
| qualification_name |
Doctor of Philosophy (PhD.) |
| qualification_level |
Doctorate |
| author |
Dheyab, Mohammed Ali |
| author_facet |
Dheyab, Mohammed Ali |
| author_sort |
Dheyab, Mohammed Ali |
| title |
Iron Oxide Encapsulated Gold Colloidal Nanoparticle Via Rapid Sonochemical Method For Mri And Ct Imaging Application |
| title_short |
Iron Oxide Encapsulated Gold Colloidal Nanoparticle Via Rapid Sonochemical Method For Mri And Ct Imaging Application |
| title_full |
Iron Oxide Encapsulated Gold Colloidal Nanoparticle Via Rapid Sonochemical Method For Mri And Ct Imaging Application |
| title_fullStr |
Iron Oxide Encapsulated Gold Colloidal Nanoparticle Via Rapid Sonochemical Method For Mri And Ct Imaging Application |
| title_full_unstemmed |
Iron Oxide Encapsulated Gold Colloidal Nanoparticle Via Rapid Sonochemical Method For Mri And Ct Imaging Application |
| title_sort |
iron oxide encapsulated gold colloidal nanoparticle via rapid sonochemical method for mri and ct imaging application |
| granting_institution |
Perpustakaan Hamzah Sendut |
| granting_department |
Pusat Pengajian Sains Fizik |
| publishDate |
2021 |
| url |
http://eprints.usm.my/52055/1/MOHAMMED%20ALI%20DHEYAB.pdf |
| _version_ |
1747822130023628800 |